We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Core houses thermal analysis suite. Researchers are able to investigate behavior of material under stress and temperature change. Service level work and technical expertise are provided.
Software platform designed to facilitate common management and productivity tasks for neuroimaging and associated data.
Center to help neuroimaging researchers to find and share data in FAIR fashion, to describe their data and analysis workflows in replicable fashion, to manage their computational resource options so that outcomes of neuroimaging research are more reproducible.
Global repository for all plant names with citation of its place of origin. Provides nomenclatural data, including spelling, author, types and first place/date of publication, for scientific names of vascular plants from family to infraspecific ranks.
Generate, archive, and distribute world-wide up to 12.000 conditional mutations across the mouse genome in mouse embryonic stem (ES) cells and Establish a limited number of mouse mutants from this resource. EUCOMM contributes the largest fraction of conditionally trapped and targeted genes in mouse C57BL/6N embryonic stem (ES) cells to the IKMC. EUCOMM vectors, mutant ES cells and mutant mice are distributed worldwide, enabling functional genomics research in a standardized and cost-effective manner by a much wider biomedical research community than has been possible previously. EUCOMM mutant ES cells and vectors can be obtained from the European Mouse Mutant Cell Repository (EuMMCR). EUCOMM mutant mice are archived and distributed by the European Mouse Mutant Archive (EMMA). Mutagenesis Strategies * Conditional gene trapping - random approach for expressed genes * Conditional targeted trapping - directed approach, used for expressed genes * Conditional gene targeting - directed approach, used for non-expressed genes
Software for mapping of molecular phenotypes that implements a new permutation scheme to accurately and rapidly correct for multiple-testing at both the genotype and phenotype levels in large-scale datasets. It is used to discover quantitative trait loci, multi-dimensional genomic datasets combining DNA-seq and ChiP-/RNA-seq.
Open source JIT compiler that translates subset of Python and NumPy code into fast machine code. Can compile large subset of numerically-focused Python, including many NumPy functions. Has support for automatic parallelization of loops, generation of GPU-accelerated code, and creation of ufuncs and C callbacks.
Software package for quantitative DNA sequencing for chromosomal aberrations providing a robust, cost-effective WGS method for DNA copy number analysis. The genome is divided into non-overlapping fixed-sized bins, number of sequence reads in each counted, adjusted with a simultaneous two-dimensional loess correction for sequence mappability and GC content, and filtered to remove spurious regions in the genome. Downstream steps of segmentation and calling are also implemented via packages DNAcopy and CGHcall, respectively.
Software tools archiving and postprocessing for reference-compressed genomic multi-alignments. It is used for creating and interfacing with Gingr files, which are archives that the Harvest Suite uses to store reference-compressed multi-alignments, phylogenetic trees, filtered variants and annotations.
Collection of eukaryotic promoters derived from published articles. Annotated non-redundant collection of eukaryotic POL II promoters, for which transcription start site has been determined experimentally. Access to promoter sequences is provided by pointers to positions in nucleotide sequence entries. EPD is structured in a way that facilitates dynamic extraction of biologically meaningful promoter subsets for comparative sequence analysis.
A Mozilla project to teach and enable users on how to create on the web. Their tools, events and teaching guides allow webmakers to create the content that makes the web great and understand how the web works. They've built everything so you can see how it works, take it apart and remix it
Software which combines the TICe and MICe measures into a two-step procedure that allows to identify relationships of various degrees of complexity in large datasets. TICe is used to perform an efficient high throughput screening of all the possible pairwise relationships and a permutation based approach is used to assess their significance.
Facility maintains large array of instrumentation for production and analysis of complex materials, including nanoparticles, thin films, polymers, ceramics, and molecular electronics.Oversees operations of Department Biological Instrumentation Cluster which provides access to specialized equipment used in molecular biology and biological chemistry.
Data collection for Xenopus laevis and Xenopus tropicalis biology and genomics.
Software for syntax highlighting for computational biology.
Web tool for prediction of sgRNAs. Helps to select optimal guide RNA for gene of interest. Support for designing guide libraries. CRISPick ranks and picks candidate CRISPRko sgRNA sequences for targets provided, while attempting to maximize on-target activity and minimizing off-target activity.
A structured controlled vocabulary of the anatomy of the Hymenoptera (bees, wasps, sawflies and ants)
Atlas of human white matter diffusion streamlines for predicting medium/long range brain connectivity. The atlas uses the popular Harvard-Oxford (H-O) cortical and subcortical atlas as endpoint targets so that WM connectivity deficits can be analyzed in conjunction with corresponding GM deficits.
Flow Cytometry Core at John G. Rangos Sr. Research Center is a BSL2+ compliant cytometry analysis and sorting facility located at the John G. Rangos Sr. Research Center in Lawrenceville serving investigators from across the University of Pittsburgh.
The Department of Pharmacology and Molecular Sciences is proud of its history. Founded in 1893 by John J. Abel, the "Father of Pharmacology" in the United States, the Johns Hopkins Pharmacology Department's advances over the years have included the first crystals of insulin, the first measurement of a drug level in a human, discovery of both the insulin and opiate receptors, and discovery of a cancer preventive principle in broccoli. Many of these and other key contributions have been made by students pursuing advanced degrees in our Department. We are also proud of our track record in student training. Many of our graduates have gone on to become academic and industrial leaders in biomedical research throughout the country and world. Not resting on our laurels, we are continuing to maintain our strong commitment to creative scholarship and education. Additionally, there is an Anti-Cancer Drug Development Training Program for predoctoral and postdoctoral students as well ad other Postdoctoral research opportunities. Each of our faculty is engaged in cutting-edge research spanning many areas including: chemical biology, immunology, virology, cancer, and neuroscience. We believe the opportunities for discovering new drug targets and developing novel therapeutics have never been brighter and will continue to be lustrous for the century ahead. The Johns Hopkins University and School of Medicine provide an excellent scientific environment, with a friendly and supportive atmosphere, filled with energetic students, faculty, fellows, and staff.