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Platform for prospective epidemiologic study conducted in four U.S. communities. One of most significant and longest running heart health studies and is the largest study of heart health in African Americans. ARIC investigates risk factors for heart disease and stroke, and connections between cardiovascular and cognitive health. ARIC includes two parts: Cohort Component and Community Surveillance Component. Cohort Component began in 1987, and each ARIC field center randomly selected and recruited cohort sample of individuals aged 45-64 from defined population in their community, to receive extensive examinations, including medical, social, and demographic data. In Community Surveillance Component, four communities are investigated to determine long term trends in hospitalized myocardial infarction and coronary heart disease deaths in men and women aged 35-84 years.
Software tool for image acquisition using WiFi-enabled Zeiss microscopes. Compatible with Windows PCs and with Apple tablets., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Custom service provider that has extensive experience in various antibody production and engineering fields.Services includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies (including phage display, bacterial display and yeast display).Conducting in depth antibody humanization and affinity maturation using phage display and DNA mutagenesis approaches.OEM services for bulk scale antibody manufacturing, including bacterial production of scFv, diabody, tandem scFv, miniantibody and Fab, and mammalian cell expression of minibody, chimeric IgG, and IgG, are also available at the most competitive price in industry.
Core offers access to computational biology capabilities. Provide services, foster long term collaborations with UAB research community, and provide training for biomedical investigators on specific set of analysis tools and techniques.Places special emphasis in areas of genomics, transcriptomics, systems biology and translational medicine. Services include data analysis, biological interpretation, grant assistance, and training.
BOC Sciences provides wide range of research chemicals and biochemicals including inhibitors, building blocks, GMP Products, impurities and metabolites, APIs for Veterinary, Natural Compounds, ADCs, Stem Cell Molecule and chiral compounds.
Software tool to perform rapid fluorescence and morphometric real time, synchronous data acquisition with IonOptix systems, as well as polynomial fitting and analysis for myocyte research. Features include data trace averaging and filtering,composite images, and transient analysis. Integrates presentation of fluorescence traces and images, analog voltages, and cell length data under intuitive interface. Analyzes raw data by performing ratio, ion, or linear calibration calculations.
Open source relational database management system that is compatible drop in replacement for MySQL database technology. Includes selection of storage engines, including high performance storage engines, for working with other RDBMS data sources. Uses standard and popular querying language. Runs on number of operating systems and supports wide variety of programming languages.Modern Relational Database SQL on JSON support.
Web based interface designed for academic research data management and research data dissemination. Accepts all file types. Enables academics to upload, share, cite and discover all manner of research outputs with security of knowing our hosting options and platform support long term preservation of data.Used to share big datasets from 100GB up. Added features and expert guidance are also included for sharing your data FAIR-ly.During data deposit, personal email support is available and once submitted, Figshare data expert will conduct review of the metadata and spot check of your dataset files and offer guidance, with main aim of enhancing discoverability and reusability.
Knowledgebase of biomedical research resources. Repository for storing validation and problematic information about variety of entities within biomedical domain, such as antibodies, cell lines, etc. Enables researchers to submit their own claims about specific entity to make validation/problematic information F.A.I.R. (Findable, Accessable, Interoperable, Reuseable).
Collaboration between research institutes working to provide framework of regulatory genomic elements in individuals with neuropsychiatric disorders.Collaboration has resulted in comprehensive set of manuscripts published in Science providing new insights into biology of developing, adult, and diseased human brain.Manuscripts are organized around three flagship articles, first analyzing human development, second studying disease transcriptomes, and third integrating tissue and single cell data with deep learning approaches.
Center for research infrastructure combining genetic engineering capabilities, advanced phenotyping and imaging modalities, specific pathogen free animal housing and husbandry, cryopreservation and archiving at BIOCEV campus. Center aims to analyze effect of loss of function gene mutations in mice with goal to produce catalog of gene function, that will help identify causative factors of human diseases as well as novel targets for therapeutic intervention. Through adoption of standardized procedures and pipelines, and usage of quality control measures and cross validation, shared goal is to produce high quality data. Center has phenotyping capabilities to accommodate both mouse and rat disease models.
Core is comprised of Materials and Molecular Analysis (MMA), Imaging and Surface Science (ISS), and Bioanalysis and Omics (BIO) centers. MMA provides instrument capabilities and expertise in spectroscopic (optical, NMR, EPR), mass spectrometry, X-ray and materials (magnetic, thermal, physical) characterization of synthetic, environmental and biological materials, both at bulk and molecular scales; BIO provides analysis of complex biological samples using modern mass spectrometry based metabolomics and proteomics approaches, including supporting cheminformatics; ISS provides analysis of complex biological and inorganic samples using near and far field imaging methods, spectroscopy, and other surface analyses.
Facility provides access to high performance computing environment, BioHPC, which includes both hosted hardware and shared machines. Provides consulting and collaborations for Bioinformatics analysis and workflows.
Provides light microscopy and flow cytometry equipment and services for ultra structural analysis of variety of sample types. Offers assisted use and training on its instrumentation and consultations on related research. Provides access to both standard and high-end imaging instrumentation to all levels of users.
Biomolecular facility equipped with JEOL 120kV and Glacios 200 kV with K2 Summit direct detector. Provides insights and high throughput data collection and analysis,single particle analysis, sample screening, and high resolution reconstruction., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Electrophysiology core facility that is part of Ion Channels and Transporters in Immunity Research Program.Research area includes ion channel and transporter function and ionic signaling in immune cells.Users who are studying other cell types or organ systems are welcome.Provides assistance with experimental design, training, implementation, and data analysis.
Core offers optical analysis instrumentation from specialized light microscopes to bioluminescence preclinical imagers to flow cytometers for multicolor cellular analysis. Services include high resolution optical sectioning of fixed cells and tissues, time lapse imaging of living cell cultures, non invasive monitoring of tumor formation in preclinical studies, and extracting specific cells of interest from tissue samples.
Set of automated workflows for common sequencing based (Illumina) protocols, such as RNA-seq, ChIP-seq, ATAC-seq, WGBS/RRBS methylation, whole genome/exome/targeted variant detection, and contaminant screening. Sequencing data analysis pipelines.
Aesthesiometer for mechanical stimulation Model 37550. Instrument designed to automate assessment of touch sensitivity on plantar surface of rats or mice and comes ready with all necessary accessories. At each paw withdrawal, automatically detects and records latency time, and actual force at time of paw withdrawal reflex. Movable force actuator is positioned below plantar surface of animal and desired force and force speed is applied, as preset by operator. Von Frey type 0.5mm rigid filament exerts increasing force, until animal twitches its paw.
Project to align physical sample identifiers. Used to design, develop, and promote service infrastructure to uniquely, consistently, and conveniently identify material samples, record metadata about them, and persistently link them to other samples and derived digital content, including images, data, and publications.