We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Web tool to visually summarise all available 3D structural information for all proteins comprising COVID-19 virus (SARS-CoV-2). Resource also gives access to structural models, generated by finding all sequence regions with detectable similarity to any currently published 3D structure. These structures are clustered into distinct states that provide insight into viral replication, mimicry, and hijacking.
Web application to help biologists use 3D structures to gain insight into protein function. Used in revealing novel insights into molecular mechanisms underlying protein function in health and disease. System for incorporating 3D structures into variant analysis.
Core is part of Edinburgh Clinical Research Facility, situated in the Centre for Cardiovascular Sciences in the Queen's Medical Research Institute. We train and host undergraduate students, PhD and post-doctoral students in practical skills and mass spectrometry operation. We have expertise in sample preparation, separation and mass spectrometry analysis for targeted small molecule analysis in clinical and pre-clinical studies. We operate under Good Clinical Practice for laboratories for clinical studies. Steroids, drugs and endogenous molecules and metabolic pathways in plasma, serum, tissue. We also have Imaging Mass spectrometry capabilities with a Waters Synapt G2Si, MALDI and DESI.
Facility offers internal and external clients experimental solutions to carry out animal studies requiring in vivo imaging, including consultations, research plan design, protocol development, data collection, analysis, and reporting. PCIC offers modalities like MRI and ultrasound enabling translational research.
Used for performing applications requiring ultimate sensitivity for ultra low level quantitation of both small and large molecules.
Software tool for modeling species niches and distributions by applying machine learning technique called maximum entropy modeling. Used for maximum entropy modelling of species geographic distributions.
Software tool for Bayesian analysis of single cell sequencing data. Used to perform statistical analyses of single cell RNA sequencing datasets in context of supervised experiments.
Software tool used to plot circular plots and visualize genomic data along genomic locations.
Software library used to tag or barcode individual cell population with unique 18 nucleotide barcodes.
Software tool to quantify comet parameters while studying DNA strand breaks. Automated tool for comet assay image analysis.
Software tool used to separate or demultiplex pooled barcodes.
Software R package used to karyoplots. Bioconductor package to plot customizable genomes displaying arbitrary data.
Software R package to help explain which variables are most important in random forests. Various variable importance measures are calculated and visualized in different settings in order to get idea on how their importance changes classification or regression model accuracy.
Software tool to detect alternative polyadenylation and identify cell type specific APA in multi cluster setting.
Software tool as fully automated pipeline for metagenomic analysis. Used for metagenomics covering all steps of analysis. Features several characteristics including co-assembly procedure or co-assembly of unlimited number of metagenomes via merging of individual assembled metagenomes, both with read mapping for estimation of abundances of genes in each metagenome. Includes binning and bin checking for retrieving individual genomes.
Software tool to calculate 2D tractions exerted by adherent cell on its substrate. Used in field of mechanobiology to study contractile responses of variety of cell types.
Software tool used in Drosophila Activity Monitor system to scann data for errors. Also allows user to extract data from monitor files and bin data in different lengths.
Software package for experimental control from Vision and Cognition Lab at Netherlands Institute for Neuroscience. Matlab based software for fMRI, Psychophysical experimentation and NHP training, with eye control using Measurement and Computing IO card. Interfaces with ISCAN eye tracker and communicates with the MRI console using trigger pulses. Uses Psychtoolbox3 graphics and control engine.
Software tool as adaptation for NHP brains and pipelines. Pycortex python based toolkit for surface visualization of fMRI data.
Software tool as guide to process NHP anatomical MRI data with adapted version of Freesurfer to generate surfaces and flatmaps.