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Provides facilities and expertise to support clinical assay development from technology developed in academic laboratories.Provides assay development and testing support for early phase clinical trials with focus on cell and gene therapy.
Facility manufactures lentiviral and retroviral vectors in support of early phase clinical trials.Services include large scale GMP lentiviral and retroviral vector and small to mid scale GMP like manufactured products. Supports certification and stability studies.
Provides analytical resource focusing on application of mass spectrometry and allied chromatographies to analysis of small molecules, generally of less than 1,000 daltons molecular weight, in complex clinical and biological samples.
Provides technical support for routine morphology based techniques. Pathologists are on hand to help guide projects, interpret results and collaborate on publications. Core personnel provide technical support for routine morphology based techniques including tissue processing and embedding, routine and special histochemical staining, immunohistochemistry, in situ hybridization, and electron microscopy.
Provides all NMR related metabolomics services on human and animal cells, biopsies and body fluids.
Shared resource lab for flow cytometry instrumentation, training, education and analyte measurement (ELISA, Luminex, IsoLight). New users need to be trained for their instrument of choice.
Supports all aspects of human pluripotent stem cell research, providing access to well characterized human embryonic stem cells and induced pluripotent stem cells for distribution to researchers. Consists of tissue culture facilities, access to microscopy and histology equipment, as well as equipment for cellular and molecular analysis of hESCs.
Clinical research support center for investigators and industry sponsors.Provides support services, research tools, experienced research personnel, and facilities to conduct or facilitate pediatric and adult clinical research from identification and development of research opportunities to phase I through phase IV clinical research trials.
Provides access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research.
Provides access to advanced analytical imaging and image post-processing methods for collaborators involved in basic and clinical research.
Supports production and analysis of DNA and RNA related data. Provides DNA and RNA sequencing, Next Generation sequencing, DNA extraction and high and low throughput SNP genotyping.
Develops high quality video and animation to enhance medical education.
Provides Cincinnati Children s Hospital Medical Center; Cincinnati; Ohio resources in confocal, wide-field, and spatial technique applications.
Supports development, scale -up and processing of innovative cell based therapies for clinical studies.
Offers imaging techniques using imaging and measurement tools. Offers consulting services ranging from educational seminars to assistance with grant and industry funding support.
Centralized resource for clinical research data management, programming for clinical research databases, and statistical analysis.
Offers services for researchers exploring cancer systems through animal models. Provides animals from specific inbred mouse strains primarily used in cancer and hematopoietic research, offers cell transplant, harvest and irradiation services and can handle animal cancer model systems involving xenotransplant procedures.
Supplies mononuclear cells, stem cells or other enriched cell populations. Provides stem cells and other tissue samples from normal donor or patient populations such as disease specific repositories or specific research studies requiring sample processing. Samples are provided fresh or cryopreserved according to availability, unprocessed or with further lab processing.Common processing techniques include PBMC isolation,Serum and plasma isolation,Separation of marker specific populations,Flow cytometric characterization of samples,Interferon gamma EliSpot.Additional services may be available upon request
Provides computational resources, services, and support to investigators including clinical research informatics, application and technology development, and bioinformatics analyses.
Offers behavioral phenotyping of rodent models as well as characterizing nervous system function in mouse and rat models through behavioral assays.