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Provides service with chemical method to synthesized any new PNA/DNA chimera where only Mmt/acetyl protected monomers can not damage the DNA part, and can synthesize any desired sequence.
Provides Fmoc based PNA synthesis. Route consists of repeated cycles of deprotection, activation, coupling and capping.Synthesis of small scale PNA oligomers, which can be performed on common DNA synthesis platforms.
Provides two chemical synthesis methods to synthesize Peptide Nucleic Acid oligomers, including Boc chemistry and Fmoc chemistry.
Provides various types of PNA conjugates and tailor made PNA products.
Open source web application development framework. Model View Controller framework, providing default structures for database, web service, and web pages.
Core with expertise in Transmission Electron Microscopy, Scanning Electron Microscopy, Light Microscopy, and supporting instruments. Staff members provide quality training and education through sessions, short courses, formal courses, open house seminars, and more.
Service in field of drug discovery and research. BOC Sciences service in one stop Proteolysis Targeting Chimeric based molecular drug discovery which has become strategy in area of drug discovery.
Provides small molecule target protein ligand service to customers to meet new drug discovery goals.
Service provider in drug discovery and development. Provides one stop PROTA development, which has become strategy in field of small molecular drug discovery. Provides peptide ligand design for target protein to customers to meet new drug discovery goals.
Service provider in drug discovery and development. Provides one stop development, which has become strategy in field of small molecular drug discovery. Provides ligand design for target protein to customers to meet new drug discovery goals.
Service provider in drug discovery and research. Provides one stop proteolysis targeting molecular drug discovery based on chimeric. Provides target protein services to customers to meet new drug discovery goals.
Provides Medium or high-throughput screening to perform rapid screening thousands of samples with biological activities at model organism, cell, pathway, or molecular levels, accelerating target analysis procedure; High content screening to analyze the way peptide compound interacts with target at subcellular level; Fragment screening to obtain higher affinity lead ligands by growing low molecular weight chemical fragments into larger drug like molecules;Virtual screening to automatically evaluate large databases with known 3D structures; Artificial Intelligence for difficult targets to support discovering and developing more drug candidates; Knowledge based design in hit identification;Hits identified by NMR screening.
Services include Value adding in vitro assays to measure biological activity of target, Characterize pharmacology and assess effects of modulating function, Synthesis of your peptide drug with reactive groups,Design experiments based on your objectives,Custom assay development,Protein expression, Cellular assays, Build cell based models,Peptide binding assays.
Services include Binding site identification and druggability assessment, Protein sequence analysis, Protein multiple sequences alignments and selectivity analysis,Analysis of available structural data and protein structure,Homology modeling for targets lacking crystal structures,Design appropriate peptides against specific targets,Water assessment.
Services include Target analysis in silico, Protein sequence analysis and Homology modeling for targets; Target analysis in bioscience, Cell based models.
Services include Structure Based Drug Discovery to design and optimize hits compounds using structural information obtained from X-ray crystallography, cryo-EM or NMR; Cell Based Drug Discovery by selecting correct cell models and culture to study pharmacological and biochemical properties; Ligand Based Drug Discovery.
Software tool as somatic and germline variant caller for amplicon data. Calls low frequency variants, on linux or windows.Runs on tumor only samples, and search for SNVs, MNVs, and small indels. It takes in .bams and generates .vcf or .gvcf files. It is included with Illumina MiSeqReporter pipeline and various BaseSpace workflows. Can also be run as standalone program.
Software tool as freely distributed computational method for analyzing distance relationships.
Software package for control of optical microscope setups with different hardware components optimized to perform multiplexed imaging experiments. Modular laboratory experiment management suite.
Instrument aboard the James Webb Space Telescope. It has two major tasks, as imager from 0.6 to 5 micron wavelength, and as wavefront sensor to keep 18-section mirrors functioning as one. Imager covers infrared wavelength range 0.6 to 5 microns. NIRCam detects light from the earliest stars and galaxies in process of formation, population of stars in nearby galaxies, as well as young stars in Milky Way and Kuiper Belt objects. NIRCam is equipped with coronagraphs, instruments that allow astronomers to take pictures of very faint objects around central bright object, like stellar systems.