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Provides services including sequencing library preparation and sequencing on Illumina MiSeq and NovaSeq 6000 platforms. Supports single cell sequencing on 10X Genomics Chromium Controller. Provides Illumina Infinium Beadchips, which includes variety of whole genome genotyping arrays as well as Infinium MethylationEPIC BeadChip.
AI powered image analysis software platform for digital pathology and related applications. Enables pathologists and scientist to easily create their own custom AI models to identify, quantify or measure different features and patterns in digitized tissue images.
Goat polyclonal antibody to tyrosine hydroxylase will reveal chatecholaminergic neurons in tissue sections and cell culture.
Goat polyclonal antibody to NF-H useful for the identification of neurons and their axons in cell culture and sections
Chicken polyclonal antibody to IBA-1, aka AIF1, is an antibody which can be used to identify microglia and other hematopoetic cells
Supports leading edge research with free access to advanced computing hardware and software.
Inferring correlations from 16S sequencing data. Capable of estimating correlation values from compositional data.
Web tool for identification of driver nodes between case control association networks.Methodology for understanding driver microbes from healthy and disease microbiome datasets.
Manual cryostat designed to accommodate needs of routine clinical laboratory by offering form fitting ergonomic design, with optional height adjustment, vacutome and cold D disinfection.
Software tool to visualize set intersections in matrix layout. Interactive, web based visualization technique designed to analyze set based data. Visualizes both, set intersections and their properties, and elements in dataset. Used for quantitative analysis of data with more than three sets.
Software package for predicting interferon stimulated human genes.
Preclinical research quality system that can be applied in public and private sectors to ensure that early drug development research proceeds along structured lines. Used for ensuring generation of reliable preclinical data. Proposes guidance on expectations for quality related measures, defines criteria for adequate processes like performance standards, and provides examples of how such measures can be developed and implemented. EQIPD certification was established by EQIPD consortium and is now managed by its legacy organisation GoEQIPD.
Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.
Software toolkit for de novo discovery of microRNAs from sRNA-seq data. Used for miRNA discovery.
Optical and fluorescence microscopy facility. Provided instruments include range of microscopes from regular brightfield microscopes to high performence LSM900- Airyscan confocal microscope. Provides Image Analysis with Imaris Full Spectrum and ClearDeconvolution software.
Provides facilities and services in process development and manufacturing of Good Manufacturing Practice grade biologic and cellular therapeutic products for Phase 1/2 clinical trials. Supports the translation of ideas from academic laboratories to clinical trials.
Provided services include Designing assays to identify and quantify immune cell subpopulations; Characterizing and measuring immune function; Monitoring immunological changes in response to both specific and nonspecific stimulation; Mass Cytometry (CyTOF, Helios); Imaging Mass Cytometry (IMC, Hyperion). Supports experimental systems to study human and mouse models by providing expertise and standardized assays to evaluate immune functions in broad range of diseases and therapies in models as well as in healthy human subjects with variable demographics.Provides services to all Mayo Clinic faculty and staff engaged in research. Selective services are available to investigators outside Mayo Clinic.
Software markerless 3D motion capture toolbox. Used for capturing precise 3D motion.
Open source platform for synchronizing multiple behavioral and physiological signals in neuroscience experiments.
Offers tools and expertise for quantitative microscopy techniques including super resolution imaging, multi photon intravital and live tissue imaging, confocal microscopy, and high speed time lapse imaging.Offers commercial and custom built microscopes, training and access to light microscopes, imaging services including whole slide scanning, MERFISH spatial transcriptomics, NanoString GeoMx DSP services, and image analysis support. Wet lab facilities, including cell culture, are also available at this BL2 facility. Imaging at BSL3 is available upon request.Offers remote imaging and data analysis sessions, including remote control of all instruments and workstations. All users are trained individually prior to use of the SCOPE equipment and workstations.