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Core facilitates all aspects of histopathology including processing, embedding, sectioning, histochemical staining, tissue microarray building, immunohistochemistry, in situ hybridisation, whole slide scanning, and image analysis.
National facility providing advanced automated chemical and genetic in vivo screening for researchers, utilizing zebrafish embryos for studying disease mechanisms. Dedicated zebrafish-focused research imaging and screening facility adapting and developing cutting edge edge microscopy for automated multiscale imaging.
Web-based application to trace tumor tissue of origin in primary and metastasized cancers.
Software DNA methylation-based algorithm, to estimate cell proportions in tumor microenvironment. Profiles tumor, immune, and angiogenic components, allowing researchers to study tumor composition and its clinical implications using archival biospecimens.
Software used for live streaming and high-quality screen recording on Windows, Mac, and Linux. Allows to capture, mix, and arrange multiple audio/video sources—such as webcams, desktop screens, and games—in real-time to create, broadcast, or record customized video content. Cross-platform screencasting and live streaming software application.
Free, secure cloud-based service used to impute missing genetic variants in human DNA data, primarily for genome-wide association studies (GWAS). It uses a massive, diverse reference panel of deeply sequenced human genomes to predict missing genotypes, significantly increasing genetic coverage and improving accuracy, particularly for rare variants. It leverages the Trans-Omics for Precision Medicine (TOPMed) panel, which includes over 400 million variants, allowing researchers to boost their genomic data from millions of SNPs to tens of millions.
Web tool for calculating Linkage Disequilibrium between variants using genotypes from selected population. We only support LD calculation for variants for which we have genotypes from at least 40 samples in the selected population. At the moment we only have sufficient amounts of genotype data from the 1000 Genomes project for human.
Uganda largest and oldest institution of higher learning, first established as a technical school in 1922, and the oldest currently active university in East Africa. It became an independent national university in 1970.
Specialized biotechnology company that provides histology services, molecular pathology services, and specialized research reagents to accelerate biomedical research. They assist scientists in academia and industry with tissue preparation, immunostaining, 3D cell culture processing, and laser capture microdissection (LCM) for cancer, neuroscience, and drug development studies.
Offers guidance and support from the very beginning of project development to data analysis. Offers hands-on, personalized support throughout experimental process including experimental design, instruments training to develop microscopy skills.
Independent, non-profit research institution closely affiliated with MIT, with many of its members holding faculty positions in the MIT Biology Department. Dedicated to improving human health through basic biomedical research.
Provides flexible, cost-efficient clinical research coordinator support across disease areas and disciplines at the University of Pittsburgh. Offers full-service or targeted, as needed support. Services include study start up, regulatory assistance, budgeting and contracting, participant recruitment and enrollment, study visit conduct, data and query management, safety oversight, blood draws, and study closeout, as well as coordinating or participating center roles for multi-site trials. CRConnect can deploy highly experienced coordinators for only the services or amount of time required, reducing costs and providing coverage for investigators without full time staffing needs. The team supports a wide range of clinical research across Pitt and UPMC systems, including IND trials (Phase I–IV), multi center studies, IDE trials, interventional and observational studies, and collaborates closely with other Pitt and UPMC shared resources to ensure investigators are directed to the appropriate support.
Software tool designed for mapping Quantitative Trait Loci (QTLs), particularly expression QTLs (eQTLs), by identifying statistical associations between genetic variants (genotypes) and molecular phenotypes (e.g., gene expression levels). Used in large-scale functional genomics projects, such as GTEx, to connect specific genetic variants to phenotypic variation. GPU-enabled QTL mapper, achieving ~200-300 fold faster cis- and trans-QTL mapping compared to CPU-based implementations.
Software end-to-end framework for perturbation analysisis. Ecosystem framework for analyzing large-scale single-cell perturbation experiments.
Software tools for correcting single cell barcodes for various scATAC-seq techniques and creating fragment files and spltting BAM files per cluster.
Software R package enables differential expression analysis on multi-sample single cell datasets using linear (mixed) models with precision weights.
Software application for rapid relatedness estimation for cancer and germline studies using efficient genome sketches extract informative sites, evaluate relatedness, and perform quality-control on BAM/CRAM/BCF/VCF/GVCF. Used for rapid relatedness estimation for cancer and germline studies using efficient genome sketches.
File format for storing nanopore DNA data in an easily accessible way. High performance file format for nanopore reads.
Software semantic segmentation method that automatically adapts to given dataset. Self-configuring method for deep learning-based biomedical image segmentation. Used to analyze provided training cases and automatically configure matching U-Net-based segmentation pipeline.
Software tools for parsing and plotting methylation patterns. Used for plotting methylation data in various ways.