Curator Dashboard

Exploris 240 system is hybrid quadrupole Orbitrap mass spectrometer with Waters H-Class Acquity, ZipChip, and DART front ends. Flexible platform for wide range of small molecule and intact protein analyses.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Exploris 480 system is hybrid quadrupole Orbitrap mass spectrometer with Waters M-Class Acquity. Proteomics system for hands on use by highly trained users.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core provides industry standard high throughput screening and automated microscopy capabilities to scientists performing drug discovery research. Provides access to automated infrastructure to support phenotypic and biochemical targets. Provides ready access to collections of current FDA approved drugs and clinical candidates exhibiting drug like qualities of acceptable solubility, desirable ADME/toxicology properties and adequate bioavailability. Has collections of mechanistically annotated informer sets that are pathway specific modulators for studying mechanism of action or target identification, collections of natural products and diverse sets of small molecules that can be interrogated for new target discovery. Each project is individually evaluated and team of scientists from CDDP is created to fit specific needs of project from assay design and development through primary, secondary and orthogonal screening.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

System includes Thermo Orbitrap Eclipse Tribid mass spectrometer and Waters M-Class Acquity nanoUPLC. This platform features sequential acquisition capabilities and multiple fragmentation types, enabling complex, in depth proteomic experiments.

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• SciCrunch
• 4 years ago - submitted by Allis Chien

Services include RNA quality control, amplification and labeling, array hybridization, scanning and data analysis, assisting customers in design and performance of microarray experiments, using Agilent (pre-made and custom) and Affymetrix arrays. Provides support for quantitation and quality assessment of DNA, RNA and protein on Agilent 2100 Bioanalyzer. Provides training and support for Agilent and Affymetrix Hybridization oven users. Provides support for microarray scanning and for data analysis with variety of software packages for both Agilent and Affymetrix platforms.Quantity and quality of your RNA, DNA, proteins and cells are determined with help of Agilent 2100 Bioanalyzer.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core mass spectrometry facility located in Department of Chemistry, University of Toronto, which houses several mass spectrometers. Services include:High resolution, accurate mass determinations of small molecules via EI, ESI and DART ionization;Mass determinations of intact peptides and proteins via ESI-QTOF-MS and MALDI-MS; HPLC-MS/MS analysis of protein digests via ESI-QTOF-MS; Quantitative analysis via HPLC-MS/MS using QqQ instrumentation.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Light microscopy core is open to HMS researchers, including Affiliated hospitals. Supports imaging modalities ranging from wide field, TIRF, spinning disk and single point scanning confocal, multiphoton, FLIM and supper resolution. Microscopes are embedded within Departments of Microbiology, Immunology, and Genetics, housed in five microscope rooms on five floors of NRB and HIM.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software tool for simulating spatially inhomogenous biochemical reaction diffusion systems for modelling cell environment feedbacks. Simulation software for spatially organised biochemical systems.

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• RRID-Legacy
• 4 years ago - by Anonymous

Software pipeline for processing and analysis of large scale spatial transcriptomics data. Enables reproducible data processing from raw sequencing data to automatically generated downstream analysis reports.

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• SciCrunch
• 4 years ago - by Anonymous

Software R package to project cells into shared embedding in which cells group by cell type rather than dataset specific conditions. Harmony simultaneously accounts for multiple experimental and biological factors. Used for integration of single cell data.

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• SciCrunch
• 4 years ago - by Anonymous

Public research university in Brazil commonly called Unicamp. Recognized as one of the best universities in Latin America.

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• RRID-Legacy
• 4 years ago - submitted by Edyta Vieth

Core is specialized in stereology techniques, live cell imaging, CLSM (confocal microscopy), and STORM. Provided instruments include CONFOCAL microscopes Zeiss LSM 5 Pascal, Olympus BX51-WI,Olympus IX71 inverted microscope, Nikon Labophot-2 microscope,Nikon Optiphot 2 microscope.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core produces mice and rats for biomedical research. Provides services for customers are researchers from Unicamp and other Institutions from Brazil.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core provides access to instrumentation essential for studies of surface and interfacial properties of materials, such as ion and electron based spectroscopies, electron, optical and scanning probe microscopies. Core provides training to students and faculty on instrumentation as well as consolation of measurements needs and data interpretation, supports educational activities involving lab tours, workshops, hands on demonstrations, outreach and broader impact related activities through our open house and lunchtime seminar series.Supports collaborative research projects with outside industrial users.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides histology (including cryosectioning, IHC and IFC) digital pathology and veterinary pathology (board certified veterinary pathologist on staff) services.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core provides cloning, expression and purification services of functional proteins at scale that meets the quantity and purity benchmarks for structural, biophysical, biochemical, and therapeutics studies; characterizes macromolecular biophysics and interaction energetics using instrumentation and techniques that can analyze association and kinetic binding constants by surface plasmon resonance, enthalpies and entropies of binding by isothermal titration calorimetry, as well as determination of stoichiometry, stability, and homogeneity by both techniques.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Statistical software tool. Predictive analytics software. Offers all tools in JMP plus advanced features for more sophisticated analyses.

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• RRID-Legacy
• 4 years ago - submitted by Anita Bandrowski

Software R package which loads SomaLogic, Inc. proprietary data file, called an ADAT file ('*.adat'). Provides auxiliary functions for extracting and manipulating relevant information from ADAT, as well as exporting modified ADAT to file.

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• RRID-Legacy
• 4 years ago - by Anonymous

Software for segmenting individual cells in microscopy images using deep learning. Cell segmentation software.

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• RRID-Legacy
• 4 years ago - by Anonymous

Software lightweight Python library for computational pipelines. Reproducible pipeline framework.

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• RRID-Legacy
• 4 years ago - by Anonymous