Curator Dashboard

Provides advanced electron imaging tools covering scale range from tens of micrometers to angstroms, and delivering valuable structural information for cell biology, microbiology, biomolecular, molecular, and materials sciences.Offers all major electron microscopy modalities.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core aims to facilitate research in cognitive neuroscience through use of Computerized Neurocognitive Battery and neuroimaging.CNB is comprised of series of tests that have been applied in neuroimaging studies and can be used either in scanner as part of functional neuroimaging study or outside scanner for measuring individual differences in performance. Tests measure accuracy and speed of performance in major domains of cognition, including executive control functions (abstraction, attention, working memory), episodic memory (verbal, facial, spatial), complex cognitive processing (language reasoning, nonverbal reasoning, spatial processing), social cognition (emotion identification, emotion intensity differentiation, age differentiation) and sensorimotor and motor speed.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Open online platform for single cell RNA-seq. Provides data management and analytics. Used to analyze public and private datasets and you can choose between several best practices workflows and browse existing analyses.

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• RRID
• 4 years ago - by Anonymous

Center to facilitate diabetes research at University of Colorado by integrating interdisciplinary basic, translational, and clinical diabetes research base; providing infrastructure and resources that are indispensable for continued discovery and progress towards diabetes research and developing improved prediction and disease prevention;providing P&F and enrichment programs to support DRC investigators and their trainees, and recruit new and young investigators into diabetes research.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

Interactive regional diabetes research community across four premiere research institutions in North Carolina, who currently garner over $70 million annually for support of their diabetes research: Duke University (Duke), The University of North Carolina at Chapel Hill (UNC), Wake Forest School of Medicine (WF), and North Carolina A&T State University (NC A&T State). NCDRC supports Research Cores that represent unique strengths at each institution.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

Multipurpose research system for high resolution Magnetic Resonance Spectroscopy and Imaging. System is equipped with 7 Tesla superconducting magnet designed with Ultra Shielded Refrigerated magnet technology. USR technology significantly reduces stray field to close to magnet. Used for In Vivo Magnetic Resonance Imaging.

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• RRID
• 4 years ago - by Anonymous

Software tool as Digital Imaging and Communications in Medicine (DICOM) viewer for medical images.

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• RRID
• 4 years ago - by Anonymous

Provides services and expertise that facilitate behavioral, psychosocial, community, translational, and population based oncology research. Services include coordinating recruitment and retention of diverse study participants representative of Sylvester South Florida catchment area;supporting development of culturally and linguistically tailored study materials; facilitating data collection and management, including for biospecimens, in clinical and community setting; assisting with development and delivery of evidence based interventions across cancer continuum from prevention to survivorship; offering, seminars, workshops and training.Offers consultation on culturally appropriate approaches for study implementation and provides translation of study materials into Spanish and/or Haitian Creole. Engages diverse stakeholders throughout South Florida in dialogue about cancer prevention and collaborative research opportunities.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides preclinical drug discovery and development services to facilitate discovery of small molecules that have potential to become cancer therapeutics.Offers expertise in drug discovery and facilitates process of uncovering novel treatments for cancer. Services include target evaluation and assay development; small molecule library preparation, screening, and curation; high throughput screening enablement; plate imaging and transfers; assay identification, development and implementation; standard and customized assays (including live cell metabolic assays, cell death assays, clonogenic assays, and alphascreen); support for hit-to-lead pharmacology (including pharmacokinetics and ADME/T); data analytics for hit-picking; investigational new drug (IND) enablement; and full pipeline project management.Offers consultation, training, educational workshops and seminars.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides small animal cancer modeling services to foster cancer research and to accelerate discovery of tailored anti-tumor therapies, including preclinical data for drug development, proof of principle for novel therapies, preclinical imaging, and disease biomarker studies. Services include facilitating in vivo modeling of human disease using mouse models; supporting preclinical in vivo efficacy and toxicity studies; devising treatment protocols; using noninvasive imaging for diagnosis and evaluation of responses to treatment; and performing histopathological analysis of targeted cancer therapies. Specific services include (1) support for the development of experimental murine models of cancer, including with cell line and patient-derived xenografts (PDXs), genetically engineered mouse models, and humanized models; (2) support for devising and implementing treatment protocols in a pre-clinical setting using murine models of human disease (e.g., drug toxicology and efficacy studies, drug formulation and delivery, and related assessments, like cell blood count, clinical chemistry, and flow cytometry analysis); and (3) diagnosis and evaluation of responses to treatment, using noninvasive small animal imaging for diagnosis and evaluation of responses to treatment, including in vivo bioluminescence and fluorescence optical imaging, high-frequency ultrasound imaging, structural and functional nuclear imaging, and magnetic resonance imaging (MRI); and (b) research histopathological analysis of targeted cancer therapies, including H&E and immunohistochemistry (IHC) sectioning, staining, scanning and analysis, and data storage of digital slide images. The CMSR also offers consultation, training, educational workshops and seminars. CMSR radiotherapy services support both small animal total body and image-guided radiation treatment delivery with sub-millimetric accuracy for development of radiation therapy regimens in a preclinical setting.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides expertise and analysis support for basic and translational research, clinical trials, and both interventional and non-interventional population-based studies. Offers support for data and large scale data analysis projects. Services include support for data analysis and interpretation; software access; algorithm and database development; support of scientific review, monitoring, and oversight of clinical and population science research protocols; consultation, training, educational workshops, lectures and seminars.Biostatistics services include support for statistical design of clinical trials, population studies, and laboratory experiments; sample size determination and justification; statistical analysis plans; statistical support for data and safety monitoring of clinical trials; data analysis and interpretation; prediction model development using machine learning techniques; and database design and data management. Bioinformatics services include project design for high-throughput genomics studies; support for next generation sequencing data analysis (including whole transcriptome profiling; targeted region gene expression and single-cell RNA-seq; epigenomics profiling such as ChIP-seq and ATAC-seq; and exome or whole genome sequencing analysis); pathway analysis; microbiome data analysis; functional metagenomics analysis; drug sensitivity and genomic association analysis; genomic data integration using public databases; integration analysis of genomic data across multiple platforms; genomic data visualization; and bioinformatics methods, analysis pipeline, software and algorithm development. BBSR services can be utilized for QA/QC, including quality assessment of sequencing data, sample outlier detection, batch effect determination, evaluation of spike-in control methods, randomized block design, and other strategies for data normalization. T

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides biorepository resources, services and expertise in support of oncology research.Facilitates translational cancer research with standard operating procedures for patient consenting; protection of patient personal and clinical data; specimen procurement and processing; quality control of specimens; secured specimen storage, retrieval, and distribution; and provision of relevant de-identified clinical data. BSSR services include: biospecimen collection, annotation, processing, storage and distribution (including tissue, blood, and other fluids); plasma, serum, and peripheral blood mononuclear cell processing and cryopreservation; rapid acquisition of surgical tissue and fresh biopsies; participant screening and enrollment for biospecimen collection studies;formalin-fixed, paraffin embedded and frozen tissue retrieval, processing, sectioning, histological staining, and digital whole slide scanning; tissue microarrays production; support for non-therapeutic trials; consultation on project design, data analysis and interpretation. Offers access tobiobank of diverse tissue types, including clinically annotated neoplastic and non-neoplastic samples from diverse anatomical sites, and provides banked specimen as well as fresh specimen procurement at institution wide level.Through BSSR, investigators have access to specimens collected fromUniversity of Miami Hospital, Sylvester Comprehensive Cancer Center, Bascom Palmer Eye Institute, Jackson Memorial Hospital, as well as to specimens collected in more broadly based multi-site studies.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core enables researchers to determine structures and dynamics, or motions, of large biomolecules such as proteins and DNA to understand how they interact with each other and with small molecules such as drugs.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Facility offers imaging spectroscopy. Equipped with Xray Photoemission Spectroscopy, Ultraviolet Photoemission Spectroscopy, Inverse Photoemission Spectroscopy, energy filtered Photoelectron Emission Microscopy, and spatially resolved Angle Resolved Photoemission Spectroscopy and spatially resolved Xray Photoemission Spectroscopy.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Facility for investigation of single crystal and powder/thin film samples by X-Ray diffraction techniques.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core for surface science, thin films studies, and nano scale characterization. Provides analytical and educational services to department and university on preparation, modification, and study of solid surfaces.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Interdisciplinary research facility in areas of imaging, nano-science and spectroscopy for measuring surface topography, surface properties, electrical measurements, fluorescence, sub-monolayer visible spectroscopy, and molecular structures.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Research facility for studying paramagnetic centers by continuous wave and pulsed EPR techniques to obtain information on electronic, chemical, and geometric molecular structures.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core provides access to state-of-the-art rodent behavioural testing equipment in facility optimized for behavioural testing. Provides expert assistance in project development, test design and execution, data analysis and interpretation, and novel test development.

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• SciCrunch
• 4 years ago - submitted by Behaviour Core

Connects industry members with Penn State research community of artificial intelligence and machine learning researchers and their students to solve real world problems and seize market opportunities.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth