Curator Dashboard

Software R package for conducting recalibration, conversion to hard probabilities, assessment of equivocal zones operations as well as calibration tools and conformal inference techniques for regression models.

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• RRID
• 1 year ago - by Anonymous

A graphic, interactive program to map quantitative trait loci by regression methods; MAP MANAGER CLASSIC enhanced by quantitative trait mapping. (entry from Genetic Analysis Software)

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• SciCrunch
• 14 years ago - by Anonymous

Lead research institution of Federal Republic of Germany and Free State of Bavaria with research mission of increasing understanding of disease mechanisms which affect human beings and essential parts of their environment. Center is divided into 28 research institutes and independent research units, which are interlinked and cooperate on various topics and in various research programs to develop new approaches to combat respiratory, metabolic and neurological diseases.The institute offers diabetes and lung information services, among others, and higher education training programs.

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• SciCrunch
• 12 years ago - submitted by Kristen Jensen

Software R package for analysis of mitochondrial DNA using sequencing data. Used for analyzing mtDNA single nucleotide variants and copy number variation. It has two components, mitoCaller and mitoCalc/fastMitoCalc.

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• RRID
• 11 months ago - submitted by Richard Culliford

The migratory locust (Locusta migratoria) is an orthopteran pest and a representative member of hemimetabolous insects. Its transcriptomic data provide invaluable information for molecular entomology study of the insect and pave a way for comparative studies of other medically, agronomically, and ecologically relevant insects. This first transcriptomic database of the locust (LocustDB) has been developed, building necessary infrastructures to integrate, organize, and retrieve data that are either currently available or to be acquired in the future. It currently hosts 45,474 high quality EST sequences from the locust, which were assembled into 12,161 unigenes. This database contains original sequence data, including homologous/orthologous sequences, functional annotations, pathway analysis, and codon usage, based on conserved orthologous groups (COG), gene ontology (GO), protein domain (InterPro), and functional pathways (KEGG). It also provides information from comparative analysis based on data from the migratory locust and five other invertebrate species, such as the silkworm, the honeybee, the fruitfly, the mosquito and the nematode. LocustDB also provides information from comparative analysis based on data from the migratory locust and five other invertebrate species, such as the silkworm, the honeybee, the fruitfly, the mosquito and the nematode. It starts with the first transcriptome information for an orthopteran and hemimetabolous insect and will be extended to provide a framework for incorporation of in-coming genomic data of relevant insect groups and a workbench for cross-species comparative studies.

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• SciCrunch
• 17 years ago - by Anonymous

Indian Institute of Technology Kanpur is a public technical and research university located in Kanpur, Uttar Pradesh. It was declared to be an Institute of National Importance by the Government of India under the Institutes of Technology Act.

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• SciCrunch
• 13 years ago - submitted by Andrea Stagg

REDCap (Research Electronic Data Capture) is a secure HIPAA compliant web-based data collection application hosted by Research and Academic Computing (ARC), a department of Beth Israel Deaconess Medical Center (BIDMC) which is itself part of Beth Israel Lahey Health (BILH). The function of the REDCap Core is to provide REDCap-related services and support to all BILH users.

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• SciCrunch
• 11 months ago - submitted by Edyta Vieth

A 501(c)(3) non-profit organization that gives out grants created to develop new therapies to control and reverse the causes of aging, as well as treat and prevent the diseases of aging. The goal is to eventually control the processes of aging, reverse their effects, and stay younger longer and ultimately create indefinite youthful, happy and productive lifespan using innovative scientific methods that are under development today in biotech companies and research labs around the world. The foundation also offers education on what we can do now to stay younger, live longer and be happier while new therapies are being developed.

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• SciCrunch
• 17 years ago - by Anonymous

Berkeley Lab is a member of the national laboratory system supported by the U.S. Department of Energy through its Office of Science. It is managed by the University of California (UC) and is charged with conducting unclassified research across a wide range of scientific disciplines. Located on a 200-acre site in the hills above the UC Berkeley campus that offers spectacular views of the San Francisco Bay, Berkeley Lab employs approximately 4,200 scientists, engineers, support staff and students. Its budget for 2010 is $707 million, with an additional $104 million in funding from the American Recovery and Reinvestment Act, for a total of $811 million.

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• SciCrunch
• 15 years ago - submitted by Andrea Stagg

Core provides support for early discovery and in vivo testing of antitumor detection and therapeutic agents. Provides resources, professional and technical expertise, and advisory services related to evaluation of agents with potential diagnostic or therapeutic activity. ATA Core works closely with investigators to establish preclinical models, including Patient-Derived Xenograft (PDX) and Patient-Derived Organoid (PDO) models, for the design and execution of pharmacokinetic (PK), toxicity, and in vivo efficacy studies. Assists investigators in determining the best formulation, administration route, and treatment schedule for each new compound, either alone or in combination with other agents.

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• RRID
• 11 months ago - submitted by Patrick Badua

THIS RESOURCE IS NO LONGER IN SERVICE, documented on June 08, 2012. The function of the IMR is to select, import, cryopreserve, maintain, and distribute these important strains of mice to the research community. To improve their value for research, the IMR also undertakes genetic development of stocks, such as transferring mutant genes or transgenes to defined genetic backgrounds and combining transgenes and/or targeted mutations to create new mouse models for research. The function of the IMR is to: * select biomedically important stocks of transgenic, chemically induced, and targeted mutant mice * import these stocks into the Jackson Laboratory by rederivation procedures that rid them of any pathogens they might carry * cryopreserve embryos from these stocks to protect them against accidental loss and genetic contamination * backcross the mutation onto an inbred strain, if necessary * distribute them to the scientific community More than 1000 mutant stocks have been accepted by the IMR from 1992 through December 2006. Current holdings include models for research on cancer; breast cancer; immunological and inflammatory diseases; neurological diseases; behavioral, cardiovascular and heart diseases; developmental, metabolic and other diseases; reporter (e.g., GFP) and recombinase (e.g., cre/loxP) strains. About eight strains a month are being added to the IMR holdings. Research is being conducted on improved methods for assisted reproduction and speed congenic production. Most of the targeted mutants arrive on a mixed 129xC57BL/6 genetic background, and as many of these as possible are backcrossed onto an inbred strain (usually C57BL/6J). In addition, new mouse models are being created by intercrossing carriers of specific transgenes and/or targeted mutations. Simple sequence length polymorphism DNA markers are being used to characterize and evaluate differences between inbred strains, substrains, and embryonic stem cell lines.

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• SciCrunch
• 17 years ago - by Anonymous

Formerly the State Science and Technology Commission, is the central government ministry which coordinates science and technology activities in the country. It succeeded the State Science and Technology Commission in 1998.

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• SciCrunch
• 15 years ago - submitted by Andrea Stagg

Core offers suite of animal imaging modalities, including MRI, PET, CT, SPECT, and ultrasound, all commonly used in clinical settings, enhancing the likelihood that findings in animal models will be translatable to human patients. Key instruments include 7.0T and 9.4T MRI systems, PET/MR, PET/CT, SPECT/CT, and advanced ultrasound systems, alongside specialized equipment including a small animal radiation therapy unit and variety of ancillary tools for advanced imaging analysis.

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• RRID
• 11 months ago - submitted by Patrick Badua

The Distributed Annotation System (DAS) defines a communication protocol used to exchange annotations on genomic or protein sequences. It is motivated by the idea that such annotations should not be provided by single centralized databases, but should instead be spread over multiple sites. Data distribution, performed by DAS servers, is separated from visualization, which is done by DAS clients. The advantages of this system are that control over the data is retained by data providers, data is freed from the constraints of specific organisations and the normal issues of release cycles, API updates and data duplication are avoided. DAS is a client-server system in which a single client integrates information from multiple servers. It allows a single machine to gather up sequence annotation information from multiple distant web sites, collate the information, and display it to the user in a single view. Little coordination is needed among the various information providers. DAS is heavily used in the genome bioinformatics community. Over the last years we have also seen growing acceptance in the protein sequence and structure communities. A DAS-enabled website or application can aggregate complex and high-volume data from external providers in an efficient manner. For the biologist, this means the ability to plug in the latest data, possibly including a user''s own data. For the application developer, this means protection from data format changes and the ability to add new data with minimal development cost. Here are some examples of DAS-enabled applications or websites for end users: :- Dalliance Experimental Web/Javascript based Genome Viewer :- IGV Integrative Genome Viewer java based browser for many genomes :- Ensembl uses DAS to pull in genomic, gene and protein annotations. It also provides data via DAS. :- Gbrowse is a generic genome browser, and is both a consumer and provider of DAS. :- IGB is a desktop application for viewing genomic data. :- SPICE is an application for projecting protein annotations onto 3D structures. :- Dasty2 is a web-based viewer for protein annotations :- Jalview is a multiple alignment editor. :- PeppeR is a graphical viewer for 3D electron microscopy data. :- DASMI is an integration portal for protein interaction data. :- DASher is a Java-based viewer for protein annotations. :- EpiC presents structure-function summaries for antibody design. :- STRAP is a STRucture-based sequence Alignment Program. Hundreds of DAS servers are currently running worldwide, including those provided by the European Bioinformatics Institute, Ensembl, the Sanger Institute, UCSC, WormBase, FlyBase, TIGR, and UniProt. For a listing of all available DAS sources please visit the DasRegistry. Sponsors: The initial ideas for DAS were developed in conversations with LaDeana Hillier of the Washington University Genome Sequencing Center.

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• SciCrunch
• 17 years ago - by Anonymous

NIH is the nations medical research agency - making important medical discoveries that improve health and save lives. The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the primary Federal agency for conducting and supporting medical research. Helping to lead the way toward important medical discoveries that improve peoples health and save lives, NIH scientists investigate ways to prevent disease as well as the causes, treatments, and even cures for common and rare diseases. NIH research impacts: * child and teen health, * men's health, * minority health, * seniors' health, * women's health, and * wellness and lifestyle issues. Composed of 27 Institutes and Centers, the NIH provides leadership and financial support to researchers in every state and throughout the world.

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• SciCrunch
• 15 years ago - submitted by Anita Bandrowski

Core provides secure receipt, processing, archiving and analysis of biological samples. Offers support for clinical research from sample collection to genetic analysis, working to the principles of Good Clinical Practice for Laboratories. Facility provides access to genomic technologies and services including next-generation sequencing (Illumina), third-generation sequencing (PacBio and Oxford Nanopore), bespoke bioinformatics analysis, and genomics and bioinformatics training.

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• RRID
• 2 years ago - by Anonymous

R package to identify differentially expressed genes from RNA-Seq data.

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• SciCrunch
• 13 years ago - by Anonymous

French national research institution focusing on computer science and applied mathematics.

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• SciCrunch
• 17 years ago - submitted by Andrea Stagg

As part of the cellular engineering and vectorology core facility (ICV), the iPSC core facility (ICV-iPS) proposes the generation and the genetic engineering of human induced pluripotent stem cells to internal research teams, external academic teams, and industrial partners. Services include generation of human iPSc with Sendai virus, full molecular and functional characterization of iPSc clones, genetic engineering of human iPSc with CRISPR/Cas9 system and theoretical and practical learning sessions on human iPSc culture. The core facility provides also access to L2 cell culture box dedicated to human iPSc culture.

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• SciCrunch
• 10 months ago - by Anonymous

Resources for macromolecular X-ray crystallography from the Richardson Laboratory, including kinemages (a scientific illustration presented as an interactive computer display), databases, software, training materials and images

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• SciCrunch
• 17 years ago - by Anonymous