Curator Dashboard

African led research unit in field of epidemiology of vaccine preventable diseases, and clinical development of life saving vaccines. Conducts translational research that informs local and global policy recommendations on infectious diseases and use of next generation and novel vaccines. Collaborates with core facilities on various trials and studies.

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• 4 years ago - by Anonymous

Automated, high performance PCR/qPCR system that uses microfluidics technology to process samples at nanoliter scale volumes for gene expression, genotyping, sample identification, copy number variation analysis and digital PCR. With wide range of integrated fluidic circuit (IFC) formats available, scaling from mid to high throughput on single system.

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• 4 years ago - by Anonymous

Pneumatic drug ejection. Used to apply ionic and non-ionic substances in small amounts. Locally precise application with microJECT pipette holder with built-in valve. Also available as 19″ stand alone device.

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• 4 years ago - submitted by Jason Bubier

Helps to advance research efforts in life sciences that cannot readily be accomplished in the traditional academic laboratory because of need for expensive instrumentation or automation, scientific or organizational infrastructure, or multidisciplinary expertise. Provides expertise and hands-on training and use of instrumentation for nominal fee. Researchers can sign up to use instrumentation through on-line scheduling system and conduct their experiments independently.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software tool for nutrition calculations and surveys.

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• 4 years ago - submitted by Nur Intania Sofianita

Core to perform expression level analysis of thousands of genes in parallel.Uses RNA-Seq assays from Tecan Genomics, Takara and Illumina for samples with limited amounts of starting RNA. Microarray technology utilizing the Affymetrix GeneChip platform is also available.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Lab houses three cores providing support and services from nucleic acid isolation through data generation on multiple genomic and molecular analysis platforms. Nucleic acid extraction, qPCR, and Nanostring profiling services are available through the Gene Profiling Shared Resource for gene expression profiling, microRNA profiling, DNA genotyping and copy number analysis, and DNA methylation analyses. Currently running QuantStudio real-time PCR system. Comprehensive RNA and DNA extraction and quality assessment services available. Massively parallel sequencing (NGS) services, including library preparation, are available through Massively Parallel Sequencing Shared Resource on Illumina NovaSeq 6000 and NextSeq platforms. 10x Genomics single-cell and single-nuclei analysis services available. Cell line authentication, DNA plating, and custom oligo services are available through DNA Services Core.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Our Investigational Pharmacy team is responsible for dispensing both inpatient and outpatient investigational medication for industry-sponsored, grant-funded and investigator-initiated protocols. We provide pharmacy services customized to each research protocol conducted at Cincinnati Children�s.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides solutions in areas of study design, bioinformatic processing of amplicon and shotgun metagenomic sequencing data, integration of metagenomic and clinical data structures, and statistical analyses of microbial community samples. MMAC works closely with Microbial Genomics and Metagenomics Laboratory to streamline workflows for metagenomic sequencing, bioinformatic processing, and statistical analysis of microbiome projects.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core facilitates study of normal and pathologic brain processes using magnetoencephalography.The purpose of the core is to make magnetoencephalography available to researchers across the institute.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software for predicting functional abundances based only on marker gene sequences.Used for prediction of metagenome functions. Contains updated and larger database of gene families and reference genomes, provides interoperability with any operational taxonomic unit (OTU)-picking or denoising algorithm, and enables phenotype predictions. Allows addition of custom reference databases.

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• 4 years ago - by Anonymous

Software R package estimates inverse covariance matrix from sequencing data.Statistical method for inference of microbial ecological networks from amplicon sequencing datasets.

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• 4 years ago - by Anonymous

Software tool used to control Plexon pattern generator for optogenetic stimulation.

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• 4 years ago - by Anonymous

Nonprofit academic medical center established in 1883. One of the oldest and most distinguished pediatric hospitals in the United States. Affiliated with the University of Cincinnati Academic Health Center.

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• 4 years ago - submitted by Edyta Vieth

Offers comprehensive CRISPR services to generate gene edited rodents and cells, and helps generate transgenic and chimeric mice via our microinjection service, cryopreserving unique mouse lines, and recovering them from liquid nitrogen storage via IVF and embryo transfer services.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides research grade retroviral, lentiviral and adeno associated virus vectors. Offers generation of stable producer lines, and non-GMP quality control testing including vector titer by functional assay FACS or PCR, endotoxin, mycoplasma, and USP sterility testing.Provides standard packaging plasmids, the investigator provides the viral vector to be used for the production run.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides facilities and expertise to support clinical assay development from technology developed in academic laboratories.Provides assay development and testing support for early phase clinical trials with focus on cell and gene therapy.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Facility manufactures lentiviral and retroviral vectors in support of early phase clinical trials.Services include large scale GMP lentiviral and retroviral vector and small to mid scale GMP like manufactured products. Supports certification and stability studies.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides analytical resource focusing on application of mass spectrometry and allied chromatographies to analysis of small molecules, generally of less than 1,000 daltons molecular weight, in complex clinical and biological samples.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides technical support for routine morphology based techniques. Pathologists are on hand to help guide projects, interpret results and collaborate on publications. Core personnel provide technical support for routine morphology based techniques including tissue processing and embedding, routine and special histochemical staining, immunohistochemistry, in situ hybridization, and electron microscopy.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth