Curator Dashboard

Provides access to tools for imaging with short lived radionuclides, data analysis and is integrated with campus centers SARIC and nuclear medicine clinic for quantitative imaging of these tracers in vivo that provides spatial and temporal data in order to improve our basic understanding of biochemical pathways, disease processes and help select personalized treatments that enhance clinical care. Highlights of our center include On-campus capacity to develop and produce radiopharmaceuticals to address specific research questions using in-vivo, real-time imaging;PET/CT, SPECT/CT (and soon PET/MRI) imaging capability to quantify organ perfusion, assess metabolic pathways, receptor function and density, and measure pharmacodynamics.Applications are directed toward range of models, ranging from small animals to non-human primates, to humans.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core services including ensurance that purified proteins and other biomolecules of interest are uncompromised in terms of their structure and stability. Facilitates analyses of catalytic activities and functional interactions.Examines thermodynamic and kinetic parameters for association between proteins and small molecules.Facilitates hypothesis generation through coalescence of experimental data and computational modeling.Assists in setting up protein crystallization assays.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides microscopes and imaging stations. Expert staff offers guide to non-expert users. Facility offers imaging expertise in Electron Microscopy, Optical Microscopy, In Vivo Imaging, and Histology.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides in vivo imaging technology to evaluate anatomy, tissue function, cellular and molecular phenotype, blood/fluid flow, metabolism and to assess pharmacokinetics and stem cell function in small animal models.Offers spatial resolution, temporal resolution, tissue differentiation, sensitivity for contrast agent, and performance of contrast agents. Services include MicroPET/SPECT/CT imaging,Ultra-high frequency small animal ultrasound imaging,Biophotonics imaging.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Core provides designing studies and developing statistical analysis plans in clinical trials, clinical and community based intervention studies, laboratory experiments, and observational studies.Provides expertise in traditional and modern statistical methods.Can help with trial design and analysis, epidemiologic analysis, sample size and power, high dimensional data analysis, risk prediction, complex survey analysis, time-to-event and longitudinal models, and statistical simulation,data management and wrangling, analytic variable coding and data set creation, research database design, data visualization, manuscript preparation, statistical programming, and much more.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides services including sequencing library preparation and sequencing on Illumina MiSeq and NovaSeq 6000 platforms. Supports single cell sequencing on 10X Genomics Chromium Controller. Provides Illumina Infinium Beadchips, which includes variety of whole genome genotyping arrays as well as Infinium MethylationEPIC BeadChip.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

AI powered image analysis software platform for digital pathology and related applications. Enables pathologists and scientist to easily create their own custom AI models to identify, quantify or measure different features and patterns in digitized tissue images.

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• RRID
• 4 years ago - by Anonymous

Supports leading edge research with free access to advanced computing hardware and software.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Inferring correlations from 16S sequencing data. Capable of estimating correlation values from compositional data.

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• RRID
• 4 years ago - by Anonymous

Web tool for identification of driver nodes between case control association networks.Methodology for understanding driver microbes from healthy and disease microbiome datasets.

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• RRID
• 4 years ago - by Anonymous

Manual cryostat designed to accommodate needs of routine clinical laboratory by offering form fitting ergonomic design, with optional height adjustment, vacutome and cold D disinfection.

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• RRID
• 4 years ago - by Anonymous

Software tool to visualize set intersections in matrix layout. Interactive, web based visualization technique designed to analyze set based data. Visualizes both, set intersections and their properties, and elements in dataset. Used for quantitative analysis of data with more than three sets.

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• RRID
• 4 years ago - by Anonymous

Software package for predicting interferon stimulated human genes.

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• SciCrunch
• 4 years ago - submitted by Haiting Chai

Preclinical research quality system that can be applied in public and private sectors to ensure that early drug development research proceeds along structured lines. Used for ensuring generation of reliable preclinical data. Proposes guidance on expectations for quality related measures, defines criteria for adequate processes like performance standards, and provides examples of how such measures can be developed and implemented. EQIPD certification was established by EQIPD consortium and is now managed by its legacy organisation GoEQIPD.

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• RRID
• 4 years ago - by Anonymous

Provides technologies that enable both qualitative (defining all components of metabolome) and quantitative (determining differential concentrations of metabolites) metabolomics in complex biological systems.Provides sensitive mass spectrometry coupled with liquid chromatography and gas chromatography for precise sample analysis. Empowers researchers with new technologies, methods development, sample analysis, expert training, and consultation.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software toolkit for de novo discovery of microRNAs from sRNA-seq data. Used for miRNA discovery.

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• RRID
• 4 years ago - by Anonymous

Optical and fluorescence microscopy facility. Provided instruments include range of microscopes from regular brightfield microscopes to high performence LSM900- Airyscan confocal microscope. Provides Image Analysis with Imaris Full Spectrum and ClearDeconvolution software.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides facilities and services in process development and manufacturing of Good Manufacturing Practice grade biologic and cellular therapeutic products for Phase 1/2 clinical trials. Supports the translation of ideas from academic laboratories to clinical trials.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provided services include Designing assays to identify and quantify immune cell subpopulations; Characterizing and measuring immune function; Monitoring immunological changes in response to both specific and nonspecific stimulation; Mass Cytometry (CyTOF, Helios); Imaging Mass Cytometry (IMC, Hyperion). Supports experimental systems to study human and mouse models by providing expertise and standardized assays to evaluate immune functions in broad range of diseases and therapies in models as well as in healthy human subjects with variable demographics.Provides services to all Mayo Clinic faculty and staff engaged in research. Selective services are available to investigators outside Mayo Clinic.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software markerless 3D motion capture toolbox. Used for capturing precise 3D motion.

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• RRID
• 4 years ago - submitted by Jensen Palmer