Curator Dashboard

Equipped with NextSeq500, MiSeq, and Ion Proton performs de novo genome sequencing, genome resequencing, ChIP-Seq and RNA-seq. Performs library construction, template preparation and sequencing of libraries or provides training in library preparation methods.Performs procedures to enrich or remove polyadenylated RNA, rRNA and/or tRNA as needed. Provides bioinformatics support for projects,data management and analysis plan before selecting samples and initiating data collection.

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• SciCrunch
• 14 years ago - by Anonymous

Software for power computation for ChIP-Seq data based on Bayesian estimation for local poisson counting process.

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• SciCrunch
• 13 years ago - by Anonymous

Software tool for HLA typing based on whole exome sequencing data and infers alleles for three major MHC class I genes. Enables accurate inference of germline alleles of class I HLA-A, B and C genes and subsequent detection of mutations in these genes using inferred alleles as reference.

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• dkNET
• 4 years ago - submitted by Ko-Wei Lin

Provides searchable public repository of genomic, proteomic and other research data for different strains of pathogenic viruses along with suite of tools for analyzing data. Data can be shared, aggregated, analyzed using ViPR tools, and downloaded for local analysis. ViPR is an NIAID-funded resource that support the research of viral pathogens in the NIAID Category A-C Priority Pathogen lists and those causing (re)emerging infectious diseases. It provides a dedicated gateway to SARS-CoV-2 data that integrates data from external sources (GenBank, UniProt, Immune Epitope Database, Protein Data Bank), direct submissions, analysis pipelines and expert curation, and provides a suite of bioinformatics analysis and visualization tools for virology research.

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• SciCrunch
• 17 years ago - by Anonymous

Provides advanced flow cytometric and morphology services at cellular and subcellular levels of resolution.Services include investigator access to equipment, education and consultation, comprehensive sample processing, data acquisition and data analysis, luminex cytokine, chemokine and growth factor quantification, and core flow cytometry services for investigator and biotech sponsored clinical trials.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

A data processing pipeline for copy number variations and aberrations (CNVs and CNAs) from next generation sequencing (NGS) data.

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• SciCrunch
• 13 years ago - by Anonymous

Core focuses on imaging in nuclear medicine, and engages in collaboration with clinicians and research investigators to optimize new instruments for applications in both clinical and pre clinical (animal) imaging scenarios. Offers equipment to build, test and characterize detectors for PET imaging, operates cluster of high powered Linux computers, which reconstruct, process, and analyze imaging data. Focuses on technology, which increases signal to noise of reconstructed images for whole body studies. Conducts research on SPECT imaging with emphasis on applications to small animal and brain imaging, oversees operation of cyclotron and imaging probe synthesis facilities.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Provides summary of gene and genomic information from eukaryotic organism databases. This includes gene symbol and full name, chromosome, genetic and molecular map information, Gene Ontology (Function/Location/Process) and gene homology, product information, links to extended gene information.

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• SciCrunch
• 17 years ago - by Anonymous

Offers high speed cell sorting and bench top flow cytometric analysis services as well as training and support to research community.Instruments include BD FACSAria Fusion Cell Sorter,4-Laser | 16-Colour (2B/3R/5YG/6V) within Class II Type A2 BioSafety Cabinet and BD LSRFortessa X-20 Cell Analyzer 4-laser | 16-Colour (2B/3R/5YG/6V).

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Effect of Deep Brain Stimulation on Parkinsonian Tremor: The recordings of this database are of rest tremor velocity in the index finger of 16 subjects with Parkinson''s disease (PD) who receive chronic high frequency electrical deep brain stimulation (DBS) either uni- or bi-laterally within one of three targets: Vim = the ventro-intermediate nucleus of the thalamus (n=3),GPi = the internal Globus pallidus (n=7), or STN = the subthalamic nucleus (n=6).

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• SciCrunch
• 17 years ago - by Anonymous

Core provides services related to single cell and bulk whole genome, RNA-Seq, ATAC-Seq, BIS-Seq, Exome-Seq, ChIP-Seq, CLIP-Seq, etc.Provides Illumina NovaSeq 6000 in addition to NextSeq and MiSeq sequencers - which all feature self-service as well as full-service operation. Offers experience with difficult, low input samples as well as sequencing and analyzing novel library types. Small Oxford Nanopore sequencer allows for full-length RNA or cDNA sequencing as well as very long read (100KB) sequencing from genomes. Offers experimental design services prior to starting your experiment.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 17,2022. Genome databases for vertebrates and other eukaryotic species. Analysis and annotation maintained on current data.Distribution of analysis to other bioinformatics laboratories. Ensembl concentrates on vertebrate genomes, but other groups have adapted system for use with plant and fungal genomes (see Powered by Ensembl list on website).

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• SciCrunch
• 17 years ago - by Anonymous

Human tissue procurement service within Department of Pathology at HUP, that assists investigators with collection, processing and preservation of research samples. Our staff will personalize sample acquisition and processing to meet project requirements. Samples (malignant, normal, diseased, etc.) and biofluids can be preserved in a range of methods (fresh, frozen, fixed, etc.).

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

Software application for high-resolution mapping of the position of a disease mutation relative to a set of genetic markers using population linkage disequilibrium (LD). (entry from Genetic Analysis Software)

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• SciCrunch
• 14 years ago - by Anonymous

Core provides services to assess cardiovascular function in mouse models and to provide validated surgical models of heart and vascular disease in mice to assess genetic or therapeutic interventions. Works with investigators to design and implement study along with any associated grant applications, animal protocol submissions and manuscript preparation. While central focus of facility is cardiovascular research, techniques employed are often useful to investigators in other fields. Helps to assess your needs and provide necessary technical training and scientific assistance in animal protocol preparation. Core runs on a fee for service model.�Accordingly, investigators will be responsible for costs incurred for their projects and prior animal protocol approval by Penn IACUC., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

THIS RESOURCE IS NO LONGER IN SERVICE, documented August 19, 2016. A database project for the neuroimaging community NeuroGenerator is a database project funded by the European Commission. The overall purpose is to make databases with data in comparable and compatible formats suited for meta research and for making models of the cerebral cortex of the human brain. Researchers can submit their own raw PET-data and fMRI data to NeuroGenerator. The data are analyzed with the statistical software package FSL. In this way databases are produced of PET and fMRI data in standard anatomical format Data as statistical parametric images in standard anatomical format immediately comparable due to the uniform processing Cytoarchitectural data (from post mortem brains) in standard anatomical format.

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• SciCrunch
• 17 years ago - by Anonymous

Core provides consultations and fee for service support in big data analyses using methods of data science in biomedical and health research related to digestive disease and liver research.

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• SciCrunch
• 4 years ago - submitted by Edyta Vieth

It is an international non-profit organization dedicated to advancing science around the world by serving as an educator, leader, spokesperson and professional association. In addition to organizing membership activities, AAAS publishes the journal Science, as well as many scientific newsletters, books and reports, and spearheads programs that raise the bar of understanding for science worldwide. :AAAS History: Founded in 1848, AAAS serves some 262 affiliated societies and academies of science, serving 10 million individuals. Science has the largest paid circulation of any peer-reviewed general science journal in the world, with an estimated total readership of one million. The non-profit AAAS is open to all and fulfills its mission to advance science and serve society through initiatives in science policy; international programs; science education; and more. For the latest research news, log onto EurekAlert!, the premier science-news Web site, a service of AAAS. :Membership and Programs: Open to all, AAAS membership includes a subscription to Science. Four primary program areas fulfill the AAAS mission: * Science and Policy * International Activities * Education and Human Resources * Project 2061 :AAAS Mission: AAAS seeks to advance science, engineering, and innovation throughout the world for the benefit of all people. To fulfill this mission, the AAAS Board has set these broad goals: * Enhance communication among scientists, engineers, and the public; * Promote and defend the integrity of science and its use; * Strengthen support for the science and technology enterprise; * Provide a voice for science on societal issues; * Promote the responsible use of science in public policy; * Strengthen and diversify the science and technology workforce; * Foster education in science and technology for everyone; * Increase public engagement with science and technology; and * Advance international cooperation in science. :

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• SciCrunch
• 14 years ago - by Anonymous

Software R package implements large collection of Bayesian regression models, including parametric variable selection and shrinkage methods and semiparametric procedures.

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• RRID
• 4 years ago - submitted by Muhammad Farooq

Freely available database focused on interactions established by extracellular proteins and polysaccharides, taking into account the multimeric nature of the extracellular proteins (e.g. collagens, laminins and thrombospondins are multimers). MatrixDB is an active member of the International Molecular Exchange (IMEx) consortium and has adopted the PSI-MI standards for annotating and exchanging interaction data. It includes interaction data extracted from the literature by manual curation, and offers access to relevant data involving extracellular proteins provided by the IMEx partner databases through the PSICQUIC webservice, as well as data from the Human Protein Reference Database. The database reports mammalian protein-protein and protein-carbohydrate interactions involving extracellular molecules. Interactions with lipids and cations are also reported. MatrixDB is focused on mammalian interactions, but aims to integrate interaction datasets of model organisms when available. MatrixDB provides direct links to databases recapitulating mutations in genes encoding extracellular proteins, to UniGene and to the Human Protein Atlas that shows expression and localization of proteins in a large variety of normal human tissues and cells. MatrixDB allows researchers to perform customized queries and to build tissue- and disease-specific interaction networks that can be visualized and analyzed with Cytoscape or Medusa. Statistics (2013): 2283 extracellular matrix interactions including 2095 protein-protein and 169 protein-glycosaminoglycan interactions.

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• SciCrunch
• 14 years ago - by Anonymous