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The Minimum Information about a high-throughput nucleotide SEQuencing Experiment that is needed to enable the unambiguous interpretation and facilitate reproduction of the results of the experiment. By analogy to the MIAME guidelines for microarray experiments, adherence to the MINSEQE guidelines will improve integration of multiple experiments across different modalities, thereby maximising the value of high-throughput research. The five elements of experimental description considered essential when making data available supporting published high-throughput sequencing experiments are as follows: # The description of the biological system, samples, and the experimental variables being studied # The sequence read data for each assay # The "final" processed (or summary) data for the set of assays in the study # General information about the experiment and sample-data relationships # Essential experimental and data processing protocols

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• SciCrunch
• 13 years ago - by Anonymous

Mikado is a lightweight Python3 pipeline whose purpose is to facilitate the identification of expressed loci from RNA-Seq data * and to select the best models in each locus.

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• SciCrunch
• 9 years ago - submitted by Luca Venturini

Software R package models, plans, and schedules flexible, such as agile, extreme, and hybrid project plans. The package contains project planning, scheduling, and risk assessment functions.

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• RRID
• 2 years ago - submitted by Kosztyán Zsolt Tibor

Maintains and distributes chromosome aberration stocks that provide primarily mouse models for Down syndrome. The Resource currently provides models for Down syndrome research, including: Rb(6.16)24Lub x Rb(16.17)7Bnr F1 hybrids that are used to produce Chr 16 trisomy (Ts16) embryos, which have many of the fetal developmental features of DS, and; Ts(1716)65Dn, segmental trisomy mice that survive to adulthood and have many of the features of DS. The Resource also includes stocks with selected reciprocal translocations involving Chr 16 and some Chr 16 transgenic stocks. In addition, a large number of Robertsonian chromosome stocks are held as frozen embryos in the Cryopreservation Resource. Each mouse chromosome is present in at least two different Robertsonian chromosomes in these strains so that specific trisomies for each of the 19 mouse autosomes can be produced. Breeding pairs and individual mice are provided.

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• SciCrunch
• 15 years ago - by Anonymous

Consortium that is an independent research initiative of the Human Research Information Network (HIRN). It is combining advances in beta cell biology and cell biology with tissue engineering technologies to develop microdevices that support functional human islets.

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• dkNET
• 9 years ago - submitted by Ko-Wei Lin

Facility dedicated to preclinical and clinical research in brain imaging in the field of mental health to foster development of new biomarkers for early diagnosis, treatment and prevention of neuropsychiatric conditions. Instruments include human (3T MRI Siemens Prisma Fit) and animal (7T Bruker Biospec) imaging equipment. Expert staff provides support for project design, acquisition and analysis. Core offers project specific conceptual assistance, 3D printing and prototyping in addition to facilities for equipment production (coil design and production). Team consists of traditional and computational neuroscientists, basic and clinical researchers, image analysts, magnetic resonance imaging physicists, and expert technologists

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• RRID
• 2 years ago - submitted by Edyta Vieth

An R package for extending the grammar of graphics for genomic data. The graphics are designed to answer common scientific questions, in particular those often asked of high throughput genomics data. All core Bioconductor data structures are supported, where appropriate. The package supports detailed views of particular genomic regions, as well as genome-wide overviews. Supported overviews include ideograms and grand linear views. High-level plots include sequence fragment length, edge-linked interval to data view, mismatch pileup, and several splicing summaries.

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• SciCrunch
• 12 years ago - by Anonymous

Database for singularity containers. It hosts container collections as well as articles about scientific advancements.

• SciCrunch
• 9 years ago - submitted by Vanessa Sochat

Small Biomarker Core provides accurate and sensitive quantitative analysis in biological samples, with or without sample processing, using state-of-the-art ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS). In addition to well qualified assays for common targets, experienced, knowledgeable personnel can provide assay development for novel targets

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Interactive repository of mutations and other allelic variations of the genes involved in the DNA repair disorders, Xeroderma Pigmentosum (XP), Cockayne Syndrome (CS), Trichothiodystrophy (TTD), and other UV-sensitivity disorders. Any omitted data or new data may be submitted by using the on-line data submission form. There is a message board system to support discussions amongst those interested in XP and DNA Repair. RESOURCES * Educational module of the molecular biology of Nucleotide Excision Repair * Introduction to the DNA Repair disorders (XP, CS, TTD, UVs) * Background on each of the XP genes * A searchable database of mutations and sequence variations for the XP genes * Contact point for the submission of new mutation data * Discussion Forums and a Guest Book * Web Links to Additional Resources

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• SciCrunch
• 17 years ago - by Anonymous

Software based on robust registration and simultaneous hippocampal segmentation and longitudinal marker classification of brain MRI of an arbitrary number of time points. The framework comprises two parts: a longitudinal segmentation and a longitudinal classification step.

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• NIF
• 9 years ago - submitted by Matt Travers

A federally funded research and development center dedicated to biomedical research. NCI-Frederick partners with university, government, and corporate scientists to speed the translation of laboratory research into new diagnostic tests and treatments for cancer and HIV/AIDS. NCI-Frederick is comprised of more than 2,800 government- and contractor-employed biomedical researchers, laboratory technicians, and support staff and several cancer research centers. The FNLCR provides quick response capabilities and meets special long-term research and development needs for NCI that cannot be met as effectively by existing in-house or contractor resources.

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• SciCrunch
• 16 years ago - by Anonymous

A biomedical ontology in the area of vaccine adverse events aimed to represent and analyze various vaccine-specific adverse events. OVAE is an extension of the Ontology of Adverse Events (OAE) and the Vaccine Ontology (VO).

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• SciCrunch
• 13 years ago - by Anonymous

Cell sources currently include fibroblasts and/or induced pluripotent stem cells for Alzheimer's Disease, Amyotrophic Lateral Sclerosis (ALS), Ataxia-telangiectasia, Frontotemporal Lobar Degeneration (FTD), Huntington's Disease, Parkinson's Disease, and healthy controls. Cell sources, including isogenic cell lines for current and new diseases covered by the NINDS will be added over the next several years.

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• SciCrunch
• 9 years ago - submitted by Isabella Froman

Tufts University offers a wide range of facilities, tools, and services available to researchers at Tufts and beyond. A core facility is a facility that performs specific technical services, primarily for the internal research operations of the University and affiliated Medical Centers, and charges users for its services, or are free to investigators as they are paid for by another funding source.

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• SciCrunch
• 14 years ago - by Anonymous

Wiki dedicated to neurosurgical topics, maintained by the Congress of Neurological Surgeons. Members can log in to contribute by adding or editing an article. A wiki is a collaborative technology for organizing information. Visitors can add, remove, and edit content. Like all other wikis, the CNS University's NeuroWiki allows linking among any number of pages. This ease of interaction and operation will engender collaborative authoring.

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• SciCrunch
• 17 years ago - by Anonymous

Software that detects kinase-specific phosphorylation sites. GPS provides a platform able to perform its prediction based on a group-based phosphorylation scoring algorithm. It allows users to query multiple protein sequences through a batch prediction mode.

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• RRID-Legacy
• 9 years ago - by Anonymous

Software as comprehensive and modular pipeline for integrated multi-omics analyses of microbiomes. Enables integration of taxonomic and functional analyses in microbiome multi-omics data.

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• RRID
• 2 years ago - submitted by Muzaffer Arikan

Ontology network about Patient Safety Incident. This work has been carried out by the Ontological Engineering Group, using sources from the University of Saint Etienne and the Australian Patient Safety Foundation.

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• SciCrunch
• 13 years ago - by Anonymous

Open source electroencephalogram (EEG) signal processing toolbox to process and visualise EEG/MEG data and other neurophysiological signals.

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• RRID-Legacy
• 8 years ago - by Anonymous