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Showing 20 out of 11,618 Resources on page 25

COMPACT

Consortium to reduce delivery and targeting bottlenecks for developing novel innovative biopharmaceutical based medicines. The project aims to shed new light on the obstacles biopharmaceuticals (medicines based on biological molecules such as proteins, peptides or nucleic acids) need to overcome to get to where they are needed in the body. The team will then use this information to develop and validate biopharmaceutical formulations to deliver these novel drugs to their targets. By finding more effective ways of administering these biopharmaceutical drugs, and improving their ability to travel through the body to where they are needed, COMPACT will allow more patients to benefit from biopharmaceuticals. Furthermore, designing less invasive administration routes and reducing the dose (and therefore the side effects) and frequency of administration will help to improve patient compliance with treatments.


DoG picker

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 18,2023. Software tool for general particle picking in the single-particle processing of unknown macromolecules. Reference free particle picker with ability to sort particles based on size or it can be used to bootstrap the creation of templates or training datasets for other particle pickers. Used to facilitate particle selection in single particle electron microscopy., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

  • Resource
  • SciCrunch
  • 8 years ago - submitted by Edyta Vieth

Versiti Blood Research Institute

Versiti Blood Research Institute is national leader in innovative blood health solutions. Provides blood and blood products to hospitals and collects blood annually. Investigators study blood disorders like hemophilia, blood cancers like leukemia, and other blood diseases.

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  • RRID
  • 2 years ago - submitted by Edyta Vieth

Systematized Nomenclature of Medicine - Clinical Terms

Ontology of SNOMED (Systematized Nomenclature of Medicine) clinical terms.

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  • SciCrunch
  • 13 years ago - by Anonymous

ConSurf Database

Collection of pre-calculated evolutionary conservation profiles for proteins of known structure in the Protein DataBase (PDB).Enables flexibility in setting the parameters of the calculation, and accepts optional uploads of atomic coordinates, multiple sequence alignments, and phylogenetic trees for use in the calculation of conservation profiles

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  • SciCrunch
  • 17 years ago - by Anonymous

Indiana University School of Medicine Cell and Gene Therapy Manufacturing Core Facility

Core collaborates with investigators through all phases of cell and gene therapy manufacturing, from pre-clinical design through treatment of patients. Facility comprises the Cell Immunotherapy and Transduction Facility (CIT), the Vector Production Facility (VPF), and the Bioprocess Development and Cell Manufacturing Lab (BDL).

  • Resource
  • SciCrunch
  • 2 years ago - submitted by Edyta Vieth

Association for the Advancement of Medical Instrumentation

A nonprofit organization made up of a diverse community of healthcare technology professionals that support the healthcare community in the development, management, and use of safe and effective medical technology. It is the primary source of consensus and timely information on medical instrumentation and technology. * AAMI is the primary resource for the industry, the professions, and government for national and international standards. * AAMI provides multidisciplinary leadership and programs that enhance the ability of the professions, healthcare institutions, and industry to understand, develop, manage, and use medical instrumentation and related technologies safely and effectively. * AAMI helps members: contain costs, keep informed of new technology and policy developments, add value in healthcare organizations, and improve professional skills and enhance patient care. * AAMI provides a unique and critical forum for members who cover a complete range of interests, from clinical and biomedical engineers and technicians, physicians, nurses, and hospital administrators, to educators and researchers, manufacturers, distributors, government representatives and other healthcare professionals with an interest in medical devices. * AAMI fulfills its mission through: ** continuing education, conferences ** certification of healthcare technical specialists ** the publication of technical documents, periodicals, books, software.

  • Resource
  • SciCrunch
  • 12 years ago - by Anonymous

Organization for Economic Co-operation and Development (OECD)

The OECD provides a forum in which governments can work together to share experiences and seek solutions to common problems. They work with governments to understand what drives economic, social and environmental change. They measure productivity and global flows of trade and investment. They analyze and compare data to predict future trends. We set international standards on a wide range of things, from agriculture and tax to the safety of chemicals.

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  • RRID-Legacy
  • 8 years ago - submitted by Joe Menke

Purdue University Flow Cytometry and Cell Sorting Core Facility

Core Facility provides instrumentation, data analysis software, training and technical expertise for flow cytometry analysis and cell sorting. Our capabilities also include the characterization of genome and transcriptomes using the Fluidigm C1 and 10X Genomics systems, in partnership with the Purdue Genomics Core Facility.

  • Resource
  • SciCrunch
  • 2 years ago - submitted by Edyta Vieth

EORTC Clinical Trials

A database that contains information about EORTC (European Organisation for Research and Treatment of Cancer) clinical trials but also clinical trials from other organizations, in which EORTC has been/is participating. The protocol database may be browsed by EORTC Research Group, tumor site, treatment, or drug.

  • Resource
  • SciCrunch
  • 12 years ago - by Anonymous

Motion Sensing Superpixels (MOSES)

Computational Python library for the motion analysis of biological single-cell and collective motion for high content screens. Framework to quantify and discover cellular motion phenotypes.


Indiana University School of Medicine Histology and Histomorphometry Core Facility

Provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility. Histology Core is core facility of the Indiana Center for Musculoskeletal Health and part of the Bone and Body Composition Core of the Indiana Clinical Translational Sciences Institute (CTSI). Histology Core provides histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared by the facility.

  • Resource
  • SciCrunch
  • 2 years ago - submitted by Edyta Vieth

Spike Sorting Evaluation Project

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 9, 2023.This project attempts to establish a platform for spike sorting with two different goals: First, to provide a sophisticated benchmark data set which could be used for future publications on this topic. Second, to give researchers using spike sorting software the possibility to evaluate their data under different conditions and compare their results to other spike sorters. Extracellular recordings are a standard procedure to analyzing the activity of neurons. A problem with this kind of recording is the simultaneous recording of not a single neuron but a small local population of neurons. It is not straight-forward to reconstruct the single neuronal activities. To estimate the single neuron activity (the so called spike train) from this multi neuron activity, spike sorting is applied. Many different algorithms for spike sorting were proposed. However, despite many efforts to tackle this problem, it is still difficult to tell under which circumstances which spike sorting algorithm is the best. If you are interested in some basic reading about spike sorting please consult the following references. A review of methods for spike sorting: the detection and classification of neural action potentials M. S. Lewicki (1998), Network: Computation in Neural Systems, Vol. 9, No. 4. (1998), pp. 53-78 Towards reliable spike-train recordings from thousands of neurons with multielectrodes. Einevoll GT, Franke F, Hagen E, Pouzat C, Harris KD (2011), Curr Opin Neurobiol. 2011 Oct 22.

  • Resource
  • SciCrunch
  • 15 years ago - by Anonymous

GSEA

Software package for interpreting gene expression data. Used for interpretation of a large-scale experiment by identifying pathways and processes.

  • Resource
  • SciCrunch
  • 8 years ago - submitted by Edyta Vieth

ggbiplot

Software R package to provide ggplot2 implementation of biplot, simultaneous plot of scores for observations and vectors for variables for principal component-like analyses.

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  • RRID
  • 2 years ago - by Anonymous

ZENODO

Repository for all research outputs from across all fields of science in any file format as well as both positive and negative results. They assign all publicly available uploads a Digital Object Identifier (DOI) to make the upload easily and uniquely citeable. They further support harvesting of all content via the OAI-PMH protocol. They promote peer-reviewed openly accessible research, and curate uploads. ZENODO allows users to create their own collection and accept or reject all uploads to it. They allow for uploading under a multitude of different licenses and access levels.

  • Resource
  • SciCrunch
  • 12 years ago - by Anonymous

4D Nucleome

Research project to understand the principles underlying nuclear organization in space and time, the role nuclear organization plays in gene expression and cellular function, and how changes in nuclear organization affect normal development and diseases. Portal provides free access to datasets, software packages, and protocols to advance biomedical research of nuclear architecture. Aims to develop and apply approaches to map the structure and dynamics of the human and mouse genomes.

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  • dkNET
  • 8 years ago - submitted by Ko-Wei Lin

DEqMS

Software R package to perform statistical analysis of differential protein expression for quantitative proteomics data.

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  • RRID
  • 2 years ago - by Anonymous

Demystifying Depression

Demystifying Depression is a wiki book on depression that is downloadable as a PDF file. This book may not have been written by a doctor. The recommendations are not referenced to actual research except in a bibliography. This document should in no way serve as a substitute for medical advice. Experts are welcome to add their comments. Depression is a mood disorder, so start many descriptions of the illness. That is a gross understatement. Depression does indeed seriously affect your mood, but that is just the tip of the iceberg. A clinical depression can be an incapacitating illness, affecting your ability to perform tasks that require concentration and rendering you unable to work. By writing this document we hope to provide you with the knowledge everyone should have about their mental well-being. Depression is not an unavoidable fate. It is physical.

  • Resource
  • SciCrunch
  • 16 years ago - by Anonymous

University of Pennsylvania Molecular Profiling Facility

Core provides full service whole genome and targeted molecular profiling of DNA and RNA on multiple platforms. The Facility offers a range of cost and performance options suitable for a variety of experimental projects. While the Facility staff performs most of the assays, investigator-performed studies are actively encouraged through the sharing of Facility procedures, individualized training of investigators or their technical staff, and use of core equipment.

  • Resource
  • SciCrunch
  • 13 years ago - by Anonymous