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Core is a specialized team of biomedical engineers dedicated to supporting MCW medical research effort by expertly designing, fabricating, repairing, and calibrating research instrumentation tailored to lab-specific needs. By providing these services in-house at a fraction of the cost of commercial vendors, the Core enables cutting-edge research while maximizing budget efficiency.
Core is responsible for overall clinical research management for studies engaging a pediatric population, both grant funded and industry sponsored clinical and translational research studies. For both Children Hospital of Pittsburgh and Magee-Women Hospital, the PCRS group provides comprehensive study engagement and helps investigators enroll research subjects. Services are available in two areas, allowing the group to best meet the needs of Pitt physicians and the patients they serve.
Core provides services primarily on animal models to enable preclinical testing and translational research, accelerating the development of human neurological therapies. It specializes in neurosurgical procedures in rodents and large animals, specializing in gene/stem cell therapy and device testing.
High-precision, tabletop or floor-standing machine used for performing static (monotonic) materials testing, including tension, compression, flex/bend, and shear tests. Designed to measure mechanical properties of materials, such as plastics, metals, composites, and adhesives, ensuring they meet quality and durability standards. Offers a force capacity range typically between 1N to 600kN.
An organization of core facilities in east Africa, spanning multiple countries whose goal is to support research, health, industry and education within Africa.
Automated, cryogen-free laboratory instrument used to measure electrical, magnetic, and thermal properties of materials. It controls temperatures from 1.8K to 400K and magnetic fields from 9T to 14T without liquid helium, using a pulse tube cooler.
Compact, benchtop super-resolution fluorescence microscope designed for single-molecule localization microscopy (SMLM) and real-time tracking, allowing imaging of fixed and live cells with a resolution under 20 nm. It enables dSTORM, PALM, PAINT, smFRET, and TIRF imaging on standard lab bench. Used for quantitative studies of biological processes, including protein interactions in fixed/live cells, extracellular vesicle (EV) characterization, and lipid nanoparticle (LNP) analysis for drug delivery research.
Digital data acquisition device used in life science research and education. It converts analog signals from sensors/transducers (e.g., blood pressure, ECG, EEG) into digital data, allowing real-time recording, visualization, and analysis of physiological signals on computer using LabChart software.
Manufacturer and distributor of high-resolution digital imaging systems specifically designed for Transmission Electron Microscopes (TEM). Based in Woburn, Massachusetts, and founded in 1990, the company specializes in developing CCD and sCMOS camera systems for life sciences and materials science applications.
Microprocessor controlled UV-Vis spectrophotometer designed for quantitative and qualitative analysis of liquid samples. Used to scan, measure absorbance, and analyze samples within 190 to 1100 nm range, specializing in nucleic acid (DNA/RNA) quantification, protein assays (Bradford/Lowry), and enzyme kinetics. It is part of DU-600 series. DU-640 features micro-focused beam technology for samples as small as 5ul, full-screen scanning, and rapid data storage/analysis without external computer.
Core provides instrumentation and service for the University of Wyoming scientific research community. Services include X-ray, Electron Microscopy, and Light microscopy analysis.
Software package for atomic model refinement and map calculation. Software for structure refinement and validation for crystallography and single particle analysis.
Software tool for filtering and trimming next generation sequencing reads.
Biosensor system designed for rapid, automated analysis of biomolecular interactions. It excels in characterizing and screening small molecule drug candidates and antibody interactions with high sensitivity, offering rapid fragment screening and affinity determination. Detects low molecular weight (LMW) compounds and weak binding interactions. Optimized for rapid screening of libraries with automated data evaluation for up to 384-well plates. Measures binding interactions in real-time without labeling.
Core provides integrated, end-to-end support for molecular biology and genomics research. Services include DNA/RNA extraction, sample quality control, genotyping, qPCR/ddPCR, and next-generation sequencing using Illumina and Oxford Nanopore platforms. In addition to laboratory services, MBGC offers consultation, experimental design guidance, troubleshooting, and training to support high-quality and reproducible research outcomes.
Core offers histological and immunohistochemical services.Our staff includes ASCP certified Histologists and American Board of Pathology certified Pathologists who provide service, assistance, and quality control. Provided services include grossing specimens, frozen and fixed tissue sectioning, routine H&E and specialized histochemical staining, cytospin preparations, IHC/IF and antibody optimizations using investigator provided antibodies. Provides training for immunohistochemical and histochemical techniques.
Core provides investigators in the Western New York area with genetically modified animals for their research through gene targeting and transgenic methodologies.
Core brings together UTM’s Growth Facilities, Imaging Facility, Life Sciences Facilities, and NMR Centre into a unified ecosystem that supports academic researchers with shared tools, expert support, and hands‑on training. Provided services include design of multi-scale experimental workflows,cross-platform training,coordinated sample preparation across scales,seamless facility operations,facilitation of data integration, and troubleshooting.
Core provides high throughput microbiology screening services and high-end mass spectrometry for diverse range of molecules.
Software toolkit for inspection, validation, repair, and reproducible processing of neuronal morphology reconstructions stored in SWC format. It provides a desktop GUI, a command-line interface, and a Python API for issue-driven curation, automated neurite labeling, radii cleaning, simplification, geometry editing, batch processing, and structured reporting.