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Modern 120 kV Transmission Electron Microscope (TEM) designed for high-throughput screening and ease of use in biological, materials science, and nanotechnology research. Resolution: Achieves 0.14 nm (High Resolution) to 0.2 nm (High Contrast) lattice resolution. Magnification: Range from x50 to x1,500,000 (HR) or x1,200,000 (HC). Imaging System: Includes a 4-megapixel, high-speed, high-sensitivity JEOL CMOS camera (NeoView) as standard, with options for a 19-megapixel (SightSKY) camera. Versatile Applications: It can be used for cryo-TEM screening, material sciences, and high-throughput asbestos analysis.

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• RRID
• 3 months ago - by Anonymous

Core services include experimental design, sample size calculation, randomization, analysis plans, data analysis, grant and manuscript preparation, full clinical trial support, and innovative targeted methods development.

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• SciCrunch
• 3 months ago - by Anonymous

High pressure, precision solvent mixing pumps designed for HPLC and preparative scale purification. They mix two different solvents to create precise gradient compositions, allowing for, or improving, the separation and isolation of target compounds in chemical or biological samples.

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• 3 months ago - by Anonymous

Compact benchtop single quadrupole mass spectrometer designed for routine, high-performance liquid chromatography (LC-MS) applications. Used for molecular weight confirmation, impurity identification, and quantitative analysis. Compatible with a broad range of chromatography platforms and ionization sources, including APCI and UniSpray, the SQ Detector 2 is the ultimate single quadrupole mass detector for chromatography.

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• 3 months ago - by Anonymous

Core oversees the operation of research animal facilities at the University of Vermont. Animal facilities houses mainly mice and rats. Animal models facilitate discovery in the areas of infectious disease, endocrinology and metabolic disease, cancer and chemotherapy, immunology and respiratory disease, among others. The University of Vermont's Animal Care program is fully accredited by the Association for the Assessment and Accreditation of Laboratory Animal Care (AAALAC, International).

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core offers streamlined, multiplexed tissue analysis services including tissue sectioning, staining, imaging, spatial RNA sequencing, analysis and interpretation of results.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Facility provides mass spectrometry-based analytical support.Houses multiple mass spectrometry platforms with complementary ionization capabilities, including EI, APCI, ESI, and MALDI, enabling qualitative and quantitative analysis of diverse sample types across a range of volatility, polarity, and molecular weight. Several systems are coupled with chromatographic separation platforms, allowing complex mixtures to be separated prior to mass spectrometric analysis. Supports research in areas including proteomics, small-molecule analysis, carbohydrate and glycosaminoglycan-related analysis, metabolomics-oriented method development, and drug-discovery-related projects.Particular strength of the Core is the analysis of complex biomolecules, including proteins, peptides, carbohydrates, and heparin/glycosaminoglycan-related samples. The Core works closely with investigators to evaluate feasibility, develop appropriate workflows, and interpret mass spectrometry data in the context of each project.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core is comprehensive data and biospecimen bank (malignant and normal tissue and their derivatives, blood and bone marrow) for research along with a range of services that accompany biospecimens. Facilitates access to human tissue, blood and bone marrow for investigators with Institutional Review Board (IRB) approved protocols emphasizing translational research. Helps investigators to establish Biospecimen and Data Research (BDR) protocols and supports the submission of grants by providing feasibility analysis, cost estimates and letters of support.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core helps research scientists and imaging core facilities produce, handle, safeguard, and share high-quality bioimage data. Ensures compliance with standards for image data management and sharing. Helps to plan experiments, track experimental conditions, and produce data.BioImage DMS eases the burden of data publication and sharing when the project is published.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Genomics core is a self-supporting core facility specializing in Sanger sequencing, SNP/fragment analysis, and Next Generation DNA Sequencing using Illumina's MiSeq platform. Provides sequencing services.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides clean rooms, cell therapy equipment, manufacturing know-how, capabilities and comprehensive suite of quality assurance and control procedures.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides consultations and services for investigators and study teams in the areas of clinical research, informatics, and data science. BRISR helps researchers harness internal and external data resources and provide informatics-driven solutions for clinical and translational research. Offers the infrastructure and processes to establish and monitor data standards, quality integration and distribution, educational and training opportunities. Provide services in three main areas: (1) Clinical data management and delivery for research, (2) Custom software development for research, and (3) Artificial intelligence analysis for clinical and bioinformatics research.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core offers services in design, oversight, implementation, analysis, publication, and reporting of scientific studies including articulating study objectives and hypotheses, grant writing, conceiving appropriate cost-effective designs and models for achievement of study objectives, monitoring interim and final analyses, and co-authoring abstracts and manuscripts.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides bioinformatics assistance for design, analysis and interpretation of genomics, proteomics and other studies for better understanding of cancer biology, thereby facilitating translation of cancer omics discoveries to cancer treatment. Provides services in design of experiments, raw omics data processing, data analysis and interpretation, data mining and integration, informatics infrastructure for data sharing and management, review and prepare grants and manuscripts, software evaluation, new method and database development,bioinformatics education and training for investigators.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides MUSC Hollings Cancer Center members with sophisticated equipment, technologies, training, and expertise required for successful, cell and tissue-based microscopic imaging and image analysis.Optical Microscopy Services include equipment and expertise to facilitate imaging of tissues and cells by Hollings members. Innovative Techniques service include development and application of new imaging techniques to meet the emerging scientific needs of Hollings members.Education and Training services include education, trainning, and consultation on imaging technologies that enable scientific discovery, including a biennial Charleston Workshop on Light Microscopy for the Biomedical Sciences, as well as a lecture series on cell and molecular imaging, especially as it relates to tumor biology.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core offers services including expert technical staff performing all aspects of sample preparation, QC, assay design and analysis. Provides integrated set of tools and services for genomic analysis. Expertise and services include clone generation, high throughput mapping, array technology development. Offers genomics platforms including data analysis, training and education on instruments and methodologies, complete discovery/screening to validation services, and full Laboratory Information Management System (LIMS) request, workflow and sample management.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Core provides highly sensitive measurements for an extensive array of chemotherapeutic agents and metabolites to support basic research and preclinical/clinical drug development.

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• SciCrunch
• 3 months ago - submitted by Edyta Vieth

Software R package extension of ggplot2 designed to create information rich plots that include details from statistical tests directly within the visual output. Used to enhance {ggplot2} plots with statistical analysis.

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• 3 months ago - submitted by Patricia Rojas

Software tool for rules for DICOM tag based labelling. Regular expression used during the SCANDAN project to label MRI scans based on DICOM tag.

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• 3 months ago - submitted by Dorian Gouzou

Label-free live-cell imaging system designed for high-content screening. Label free live cell imaging microscope allows to instantly observe and analyze the inside of living cells in 3D without using toxic stains, leveraging AI-powered digital assays and holographic tomography to automate workflows and provide fast, high-resolution data.

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• 3 months ago - by Anonymous