We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software tool as graph self-supervised contrastive learning method that combines graph neural networks with self-supervised contrastive learning for spatial clustering, multi-sample integration, and cell-type deconvolution of spatial transcriptomics data.
Resources to support implementation of BRCA testing through routine oncology appointments.
Software application for opening and reviewing EDF, EDF+, BDF, and BDF+ biomedical-signal recordings in a multi-document Windows x64 workspace. It provides channel organization, navigation and scaling, measurements, annotation browsing and separate sidecars, selected-region frequency inspection, and review exports within documented limits while leaving source recordings unchanged. The current release is a public preview for waveform review, education, software validation, and research support; it makes no diagnostic interpretation claim.
Confocal Raman imaging microscope for automated molecular and chemical characterization and spatially resolved Raman mapping. Supports high-resolution chemical imaging and analysis of heterogeneous samples. Used to map, identify, and visualize the chemical and molecular composition of a sample in real time.
Core provides advanced instrumentation and expertise for the identification, characterization, and quantification of chemical compounds in a wide range of research samples. Instrumentation and capabilities include liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF), gas chromatography-mass spectrometry (GC-MS), high-performance liquid chromatography (HPLC) with diode array, fluorescence, and refractive index detection, inductively coupled plasma-optical emission spectrometry (ICP-OES), Fourier-transform infrared spectroscopy (FTIR), UV-Vis-NIR spectroscopy, and fluorescence spectroscopy. Provides expertise in analytical method development and optimization, sample preparation and analysis, data analysis and interpretation, experimental design, and training in analytical instrumentation and methods.
Functional genomics experiments based on DNA array technologies, either under the platform of cDNA or oligonucleotides, is the dominant technology. Any of the platforms used generates an array of gene expression (GEM). Discounting the laboratory artifacts introduced during the obtention of a GEM, one of the main limitations of these techniques is that the statistical analysis is complex and requires specialized software applications. The Bioconductor project has produced a lot of routines developed in R, which are oriented to analyzing functional genomics experiments. These routines are computationally efficient, are stable and are optimized for the analysis of gene expression arrays. However, its use requires a high level of specialization, which involves handling concepts and object-oriented techniques and be familiar with the syntax of the R programming language. Most biologists and biotechnologists do not have the necessary training to use these routines and this circumstance forces them to rely on data analysis services. Moreover, every analyst knows that the analysis process requires successive approximations and this implies that the researcher has to repeat the analysis from different perspectives or under various scenarios, which is not possible when you depend on a standardized processing service. It is therefore important that researchers could have friendly tools for the analysis of functional genomics data. fgStatistics is a software with a visual interface that takes advantage of the enormous potential of the R platform and packages specifically routines, developed in the framework of Bioconductor, to offer a freeware tool that covers the basic needs of a biologist or biotechnologist for data analysis DNA microarrays. Additionally, for advanced users, offers a programming interface that allows R use the full potential of this language without leaving the workplace and accessing data structures and objects that generate procedures with friendly interfaces.
LinRegPCR is a program for the analysis of quantitative RT-PCR (qPCR) data resulting from monitoring the PCR reaction with SYBR green or similar fluorescent dyes. The program determines a baseline fluorescence and does a baseline subtraction. Then a Window-of-Linearity is set and PCR efficiencies per sample are calculated. With the mean PCR efficiency per amplicon, the Ct value per sample and the fluorescence threshold set to determnine the Ct, the starting concentration per sample, expressed in arbitrary fluorescence units, is calculated
Core provides services, including secondary data, a participant pool for independent sampling, in-house software to collect responsive fine-grained mobile Health data from participants, support for network sampling and analytic approaches, and consultation in field-based biospecimen testing, epidemiological data collection, respondent driven sampling, prevention/intervention design, and research with hard-to-access populations.
Core facilitates faculty development, provides programmatic enhancements, creates engagement opportunities, coordinates center operations, mentors early-stage faculty, and manages grant development for rural substance use research.
Software tool to identify and annotate tandem repeats in genome assemblies. Tandem repeats annotation tool.
SOPHiA DDM™ is IVDR-certified* genomics platform that leverages AI algorithms to accurately pinpoint signals within noisy, complex next-generation-sequencing (NGS) datasets. It seamlessly integrates into any genomics workflow to identify causative variants.
Australia's national facility for recombinant protein and biologics, spanning research-grade protein production through to Phase I clinical-grade biomanufacturing. Multi-host expression and end-to-end development for research, industrial and therapeutic use, supporting mAbs, ADCs, radioligand therapeutics, vaccines and beyond, under one ISO 9001 certified quality system.
Software R package to create visualizations of categorical data. Mosaicplots in the ggplot2 framework.
Institute for Biomolecular Targeting at Dartmouth College is NIH-funded research center that bridges basic biological discovery and clinical translation for complex diseases like cancer, infections, and neurological conditions.
R package that uses cell-type labeled spatial omics data to identify colocalization or separation of cell types at different length scales.
Software R package for single-cell genomic data analysis. Includes DecontX, a method to estimate and remove ambient RNA contamination from single-cell RNA-seq count data.
Benchtop, air-driven high-shear fluid processor used to lyse cells, create uniform nanoemulsions, and formulate drug-delivery nanoparticles from small sample volumes. Pneumatically driven benchtop high-shear homogenizer.
Software application designed to analyze laboratory experiments conducted on microplates.
Software R package for computing species association and niche overlap. Used for analysing species association and niche overlap.
Software R tools for integrating phylogenies and ecology. Includes functions for analyzing the phylogenetic and trait diversity of ecological communities, comparative analyses, and the display and manipulation of phenotypic and phylogenetic data.