We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Software application as starting point to MoSeq2 package suite. Unsupervised machine learning method which takes inputs from depth cameras in 3D and transforms them into different behavioral motifs which called syllables. Used to extract mouse pose from depth video and model how pose evolves over time.
Software R package for Orthologue assignment and Integration of single cell data. Functions for Orthologue Assignment and Integration of Single Cell Data between species.
Software tool used to calculate FRET efficiency on pixel-by-pixel basis from ratiometric FRET images. Allows to correct for channel cross-talk and to calculate FRET from image stacks, i.e., from 3D data sets. ImageJ plugin for intensity-based three-filter set (ratiometric) FRET.
Software tool for analysis of acceptor photobleaching FRET images. Allows fully corrected, pixel-wise calculation and detailed, region of interest based analysis of FRET efficiencies in microscopic images.
SDI is composite measure of area level deprivation based on seven demographic characteristics collected in the American Community Survey and used to quantify the socio-economic variation in health outcomes.
Inverted microscpe for visualization of live cell culture.
Multi-mode microplate reader with three detection modes.Utilises ultra-fast UV/vis spectrometer or filters for absorbance as well as highly sensitive filters for all other detection modes.
Software R package that performs sparse factor analysis and differential gene expression discovery simultaneously on single cell CRISPR screening data.
Digital library of Internet sites and other cultural artifacts in digital form. Web history is accessible through Wayback Machine and they work with 1,200+ library and other partners through Archive-It program to identify more important web pages.
Histology multistainer produces results for both routine and special stains and can perform single or multiple protocols at the same time. Contains 12 slide racks and 34 reagent stations.
Platform for archival digital glass slide collection containing digital whole slide images from Lewy body disorders: Parkinson’s Disease, Parkinson’s Disease with Dementia and Dementia with Lewy Bodies, and control cases.E stained post-mortem brain tissues from patients with neurodegenerative diseases and controls.
Global repository for all plant names with citation of its place of origin. Provides nomenclatural data, including spelling, author, types and first place/date of publication, for scientific names of vascular plants from family to infraspecific ranks.
Database of digitized plant specimens. Used for finding plant name, type, specimens and their label data.The collection also includes partner contributed reference works and primary sources. Used for research and teaching in botany, ecology, and conservation studies.
Software package for general purpose sequence search and counting program for FASTQ files. Python3 program that counts sequence occurrences in raw FASTQ files. Used for CRISPRi-Seq, and for extracting and counting any kind of information from Illumina reads, such as barcodes.
Software tool to identify important genes from genome-scale CRISPR-Cas9 screens. Used for prioritizing single-guide RNAs, genes and pathways in genome-scale CRISPR/Cas9 knockout screens.
Provides systematic review literature searching services, writing review services, and resources in print and electronic format to faculty, students, and researchers in the schools of the health sciences. The Library also manages the SPSS and EndNote licenses for the campus.
Web server to check whether given list of genes can be associated with stemness. Used to identify sets of genes considered essential to define stem cells. Used to explore presence of stemness signatures in user-defined gene sets. Analysis tool, based on curation of published stemness signatures defined by gene expression, RNAi screens, Transcription Factor binding sites, literature reviews and computational approaches.
Software tool as set of Python scripts to modify GROMACS topology files, by adding content from different topology files and other GROMACS input files. Useful, particularly when system components are assembled outside of GROMACS, or in different steps within GROMACS. This helps prevent users from having to copy and paste significantly large blocks of text within topology files.
Core facility is dedicated to structural characterization of biological samples and microcrystals using cryo-electron microscopy. CryoEM workflows including, single-particle CryoEM, Cryo-electron tomography , and Micro crystal electron diffraction. Instrumentation includes TFS 200kV Glacios CryoTEM, equipped with zero-loss Selectris Energy Filter, Flacon 4i Direct Electron Detector, and Ceta-D camera, Pelco Easy Glow Discharger, TFS Vitrobot Mark IV, and Leica EM GP2. We also present all the capacities for storing and shipping samples. Facility has Data storage Server and Live processing workstation for our users� convenience, including data processing suites RELION and CryoSPARC available at our campus supercomputer Swan cluster at the Holland Computer Center.
Core offers education, analysis, and computational services in the area of bioinformatics and computational biology. Offers initial consultations to help with experimental design and power analysis of 'omics data for grant submissions and bioinformatics needs for current projects.