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Roche Diagnostics develops and produces medical tests and digital tools that provide information to help healthcare professionals find the right treatment for patients and deliver the best patient care to improve, prolong and save lives.
Simple Western blotting device that performs capillary based immunoassays and fully automated Western blot analysis. Automates protein separation and immunodetection of traditional Western blotting.Traditional Western blotting steps of sample separation, wash buffer incubations, and immunodetection of target proteins occur inside hands free capillary instrument.
Platform containing informative videos on stroke care and rehabilitation which was created in collaboration with multidisciplinary team of healthcare professionals.
Software pipeline to handle data from PacBio and Oxford Nanopore platforms. Pipeline does read alignment, corrects for mismatches, microindels and non-canonical splice junctions and then provides quantitations and QC-metrics.
Provides distributed services from Universities of Connecticut, Georgia, and Wisconsin to democratize application of high-field NMR spectroscopy for applications in biomedicine, materials science, and chemistry. Multi-institution collaboration creating distributed research infrastructure for NMR applications including resource discovery, access to NMR spectrometers, ranging from bench top to ultra-high field, knowledgebases on best practices, and data archiving and sharing.
High Performance Computing cluster consisting of Linux compute servers with processing power and memory for running large, long or GPU-enabled jobs.
Scientific Imaging is comprised of Microscopy Lab, µCT Imaging Center (mCTIC), and Scientific Visualization Center (SciVis). Facility is user driven research core in support of National Museum of Natural History life sciences research. Provides preparation and examination of natural history specimens for scanning electron microscopy, stereo light microscopy, compound fluorescence microscopy, X-ray micro-computed tomography and 3D laser scanning. Produces reconstructed volumes of scanned specimens. Provides reconstruction, segmentation, analysis and animation of 3D datasets.
FAIROS Research Coordination Network. Mirroring NSF’s “10 Big Ideas” of Convergence Research the Non-Clinical Tomography Users Research Network (NoCTURN) will leverage input from broad community of tomography educators, researchers, and industry stakeholders to propose improvements to data handling that cut across scientific disciplines. Primary goal is to develop practical recommendations that link today’s tomography data with tomorrow’s tomography discoveries.
Natural history museum administered by Smithsonian Institution, located on the National Mall in Washington, D.C., United States. Houses specimens and artifacts, which are mostly animals preserved in formaldehyde. Digital records are available online.
Facility offers cell analyzers and cell sorters as well as expertise in large range of traditional immunophenotyping and small particle, geo-physical applications.
Facility provides technical and educational support for fluorescence based single cell analysis and isolation to further the characterization and understanding of cellular function, biomarkers, pathology, and treatment in basic, translational, and clinical research projects.
Software tool to support translation of basic research in medical image analysis into early clinical studies.
Provides specialized resources and expertise to support scientists that want to incorporate systemic measures of mouse activity, metabolism and feeding. The systems are also embedded within light regulated environments to capture circadian, time of day, based outcomes.Supports scientists wanting to perform circadian type analyses with either pre-clinical or clinical time series data. Supports scientists wanting to incorporate -Omics measures into their studies with experience in genomics, proteomics and metabolomics assays/analyses. These services are available to support new investigators, early-stage investigators and current investigators in aging.
Core for understanding Earth surface processes in bedrock, soil, water, and sediment. Interactions between cosmic rays and Earth’s upper atmosphere create unique isotopes both in the atmosphere and in materials on Earth’s surface. By assessing the ratios and/or concentrations of these isotopes, we can get a deeper insight into the exposure age, soil production rate, catchment-averaged erosion, and processes of Earth’s varied landscapes.
Software image analysis tool for digital pathology and spatial biology researchers.
Core facility houses the capability to test water using multiple instruments and techniques including : Ion Chromatography, which is an analytical technique for determining the concentration of anions in aqueous solutions such as fluoride, chloride, nitrate, phosphate and sulfate; Carbon and nitrogen analysis, which incorporates measurements of total carbon, total inorganic carbon and total organic carbon together with total nitrogen; and other parameters such as pH, alkalinity, turbidity, conductivity (and others) using instrumentation and kits.
Magnetic resonance imaging research facility located at University of Colorado Boulder.
Offers services from sample preparation to image processing.Provides instrumentation for use such as electron microscopy, light microscopy, and access to other instrumentation for use in sample prep.
Integrated core offers services in Irradiation, pre-clinical imaging of small and large animals, light and electron microscopy, large and small animal cancer models. Irradiation Section assists investigators in radiation treatment planning and delivery of ionizing irradiation to cells, rodents and large animals with engineered, transplanted or spontaneous tumors.Imaging Section provides technologies for non-invasive, whole-animal imaging of animals used in preclinical research studies. Microscopy Section provides access to point scanning confocal microscopy with Airyscan super resolution, conventional bright field and fluorescence light microscopy, high throughput live imaging, automated slide scanning and image analysis resources. Electron microscopy resource provides scanning transmission electron microscopy. Animal Cancer Models section supports generation and utilization of large and small animals for modeling cancer and other human diseases. Section has expertise in generating cancer models using wild type or genetically engineered animals in immunocompetent and immunocompromised backgrounds, as well as mice with humanized immune system.
Facility provides imaging instrumentation and analysis software along with training and expertise.Instrumentation and technologies available to users include Zeiss LSM800 AIRYSCAN confocal microscope integrated with Zen software; PerkinElmer / Akoya Vectra 3.0 Automated Quantitative Pathology Imaging System;Agilent/BioTek Cytation 5 with BioSpa8 live-cell microscopy system for fluorescence and phase contrast microscopy; Olympus IX-83 ZDC2 microscope equipped with PRIMO UV light-based bioengineering device for micropatterning and microfabrication; Olympus IX73 Inverted Fluorescence Microscope.Image analysis software hosted on appropriately powered workstations with cloud connectivity for high capacity storage: HALO3, Inform, Volocity, AutoDeblur, Image-J / Fiji.Transmission and scanning electron microscopy including FEI Talos F200i (200kV TEM and STEM electron microscope (TEM), equipped for micro-analysis, and cryo-EM;FEI Helios CX5 dual beam FIB-SEM system with X-ray microanalysis detectors; instruments for specimen preparation for transmission and scanning electron microscopy including ultramicrotomes Leica Ultracut UC6 and UC7, critical point dryer Samdri-970, Leica ACE 600 coater and ThermoFisher Vitrobot.