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Provides services including High-resolution imaging of bacteria and parasites, and their interactions with host eukaryotic cells; High-resolution imaging of biological processes of larger eukaryotic cells, spheroids, tissues and organs including the use of micro-fluidic devices. Provides equipment for biological specimen preparation for optical and electron microscopy. Provides training and support on the use of both basic and advanced microscopes including:transmitted light, wide-field fluorescence, confocal laser-scanning, super-resolution, high-content imaging, slide-scanning microscopy and range of image analysis and 3D-image visualisation software like FIJI, Huygens, Leica AIVIA, ZEISS ZEN Intellesis and Bitplane Imaris.
Software tool to calculate p-distance matrix based Variant Call Format.
Software wrapper command for command neighbor of the PHYLIP package. Implements Neighbor-Joining method of Saitou and Nei and UPGMA method of clustering. Constructs tree by successive clustering of lineages, setting branch lengths as the lineages join.
Software package for parentage analysis in plant and animal populations. It combines robust likelihood-based method with simple graphical interface.
Software R package to assign offspring to their parents without any prior information other than offspring and parental genotypes, and user-defined, acceptable error rate among assigned offspring. Auto-adaptive parentage inference software that tolerates missing parents.
Software R library for parentage assignment using Bi-Allelic Genetic Markers. Used for assignment of parentage with molecular markers. Improved paternity assignment among close relatives using simple exclusion method for bi-allelic markers.
Develops and supports KeyMolnet integrated platform for bioinformation, and provides analysis services using KeyMolnet. KeyMolnet provides support for disease mechanism analysis, drug discovery target discovery, expression data analysis obtained by microarrays and high-speed sequencers, and data analysis such as proteomics and metabolomics, based on molecular network information, disease information, and drug information collected by our researchers from the latest papers.
Laboratory scale ultrasonic processor for nanoparticle dispersion, emulsification, cell lysis, homogenization, particle size reduction, and wide range of other applications.
Web tool facilitating the conduct and assuring for the documentation of systematic reviews, systematic maps and further literature reviews.
Reporting guideline published in 2015 and aiming to facilitate the development and reporting of systematic review protocols.
Software platform to annotate cell types.
Software tool extension to ImageJ for spinal cord. Used for efficient preparation and imaging of whole spinal cord and the absence of 3D reference atlas.
Software application as helper to run command, capture stdout/stderr and details about running.
Software toolkit to identify and visualize cancer neoantigens. Cancer immunotherapy tools suite consisting of following tools: pVACseq as cancer immunotherapy pipeline for identifying and prioritizing neoantigens from VCF file; pVACbind as cancer immunotherapy pipeline for identifying and prioritizing neoantigens from FASTA file; pVACfuse as tool for detecting neoantigens resulting from gene fusions; pVACvector as tool designed to aid specifically in construction of DNA-based cancer vaccines; pVACview as application based on R Shiny that assists users in reviewing, exploring and prioritizing neoantigens from results of pVACtools processes for personalized cancer vaccine design.
Web server predicts peptide binding to any MHC II molecule of known sequence using Artificial Neural Networks.
Core provides secure receipt, processing, archiving and analysis of biological samples. Offers support for clinical research from sample collection to genetic analysis, working to the principles of Good Clinical Practice for Laboratories. Facility provides access to genomic technologies and services including next-generation sequencing (Illumina), third-generation sequencing (PacBio and Oxford Nanopore), bespoke bioinformatics analysis, and genomics and bioinformatics training.
Provides tools and expertise in bio image analysis, histology, and microscopy. Facility allows for the preparation, visualization, and quantification of biological samples at the cellular and sub cellular levels. Researchers can choose to utilize our instruments independently or collaborate with our skilled staff through our fee-for-service options.
Design of SAKR-M device includes computer, pneutronic unit, spirometric sensor, finger cuff, ECG electrodes and power supply adapter. Used for functional diagnostics of nervous regulation of blood circulation. Integrated method of studying cardiorespiratory system to analyze heart rate variability , arterial blood pressure variability and respiratory patterns.
An integrated method of studying the cardiorespiratory system—spiroarteriocardiorhythmography (SACR) (“Intox”, Russia)—was applied to analyze heart rate variability (HRV), arterial blood pressure variability (BPV) and respiratory patterns. This device was recommended for use in medical practice by the Ministry of Health of Russia (registration certificate No 29/03020703/5869-04) and combines three physiological methods into an integrated hardware complex.