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Provides technology and service capabilities in super resolution microscopy, image analysis, immunohistochemistry, and histopathology services. Provides consultations and technical support on histopathology services and experimental design.
Clinical oncology database sourced from hospital registry data collected in Commission on Cancer-accredited facilities. These data are used to analyze and track patients with malignant neoplastic diseases, their treatments, and outcomes.
Software workflow begins by preprocessing short-read samples of raw data to create counting colored De Bruijn graph. Graph based method for population genotyping of small and structural variants. Population genotyping workflow.
Software package built for in-depth analyses of tRNA-derived small RNAs (tDRs), mature tRNAs, and inference of RNA modifications from high-throughput small RNA sequencing data. Used for integrating analysis of tRNAs, tRNA-derived small RNAs, and tRNA modifications.
Software tool to assist with manually counting objects in images. Used for many conservation applications.
Software to detect DNA splint sequence raw reads. Computational pipeline for calling consensi on R2C2 nanopore data.
Software for DNA sequence clustering. General purpose DNA sequence clustering tool with strong focus on error correction.
Software Pacbio analysis tool. Deconcat PacBio reads.
Software package to identify transcripts in PacBio single-molecule sequencing data. Scalable De Novo isoform discovery from single-molecule PacBio reads.
Software R package for power calcualtions. Basic functions for power analysis.
Software for scientific image capture and analysis.
Software repository, raw data, and results data for the PlasGO manuscript.
receptors function database Insufficient Information letter sent
Core provides services and expertise in the areas of proteomics, metabolomics, small molecules, and molecular interactions. The staff can assist in data collection for experiments as well as provide help in experimental design and data analysis. Value added work such as grant writing and publication methods/figures is provided free of charge.
Offers manufacturing of cellular and biologics for safety and initial efficacy testing in first–in– human, pilot, and Phase I clinical trials. Facilitates bench–to–bed translation into novel cellular therapies. Provides focused scientific, technical, and regulatory support for investigator-initiated investigational new drug applications (INDs) in cell and gene therapy. Current and completed trials include hematologic malignancies multiple myeloma, breast cancer, prostate cancer, glioblastoma, neuroblastoma, and pancreatic cancer. The potential applications of cellular therapy and biologics are not limited to cancer, a large number of disease indications such as cardiovascular, autoimmune diseases, diabetes, neurological diseases, etc.
Promotes the expansion and enhancement of clinical research that incorporates exercise physiology and body composition into research questions. Offers measures of resting and exercise oxygen consumption, lactate threshold assessment, endothelial function, regional distribution of body fat, body composition assessment, anthropometry, and the use of acute exercise and/or exercise training as an intervention.
Core provides services to produce and preserve genetically engineered mouse strains for animal model research.Supports animal model research endeavors, to advance genetic and reproductive technologies for model creation and preservation, and to serve as resource for design, development and derivation of customized mouse strains.
Core specializes in imaging small animals and samples with variety of modalities depending on the investigator’s needs. These modalities include MRI, X-Ray CT, PET, SPECT, luminescence, and fluorescence. We work closely with the Radiochemistry Core Lab which can synthesize custom, targeted PET and SPECT imaging agents.
Provides access to high-quality novel and existing radiopharmaceuticals (radiolabeled small molecules, peptides, proteins, and antibodies), that can be imaged by Positron Emission Tomography (PET) method, to meet their preclinical and clinical needs. Radiochemistry core is Good Manufacturing Practices (cGMP) certified facility as required by the U.S. Pharmacopeia Chapter 823 and 21CFR part 212 and is BSL-2 certified facility to conduct research.
Core provides standard and customized research specific histology services including routine formalin fixation and paraffin embedding, and sectioning, automated Hematoxylin and Eosin staining as well as selection of manually prepared special stains and preparation of frozen section.