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University of Copenhagen Novo Nordisk Foundation Center for Basic Metabolic Research Metabolomics Platform Core Facility is equipped with a high resolution mass spectrometer with two distinct separation technologies - a second generation dual Trapped Ion Mobility Spectrometry (TIMS) analyzer which provides collision cross section values and Parallel Accumulation Serial Fragmentation (PASEF) which allows downstream selection of precursor ions for fragmentation. The mass spectrometer is coupled with an Agilent 1290 Bio UPLC, with binary solvent pump, multi-sampler and thermostatted column oven. Insufficient Information letter sent. NO picture and description of the instrument on the core page. they have similar instrument already

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• 2 years ago - submitted by Mansa Nair Kihara

The HT7700 is a transmission electron microscope (TEM) by Hitachi, known for its high-resolution imaging capabilities. It provides detailed visualization of internal structures at a sub-nanometer scale, making it ideal for research in materials science, biology, and nanotechnology. The HT7700 offers versatile imaging modes and user-friendly features, enabling both detailed analysis and ease of use for a wide range of samples.

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• 2 years ago - submitted by 涛宣 文

Inositol is a sugar alcohol involved in cellular signaling and metabolism, crucial for insulin sensitivity, lipid metabolism, and neurotransmitter function. The most common form, myo-inositol, is used as a dietary supplement for potential benefits in mental health and managing polycystic ovary syndrome (PCOS). It is naturally present in foods like fruits, beans, grains, and nuts.

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• 2 years ago - submitted by 涛宣 文

Paclitaxel is a chemotherapy medication used to treat a variety of cancers, including ovarian, breast, lung, pancreatic, and other solid tumor cancers. It belongs to a class of drugs known as taxanes, which work by stabilizing microtubules and inhibiting their disassembly, thus disrupting the normal function of the mitotic spindle and preventing cell division. This disruption leads to cell death, particularly in rapidly dividing cancer cells. Paclitaxel is commonly administered intravenously and is often used in combination with other chemotherapy agents to enhance its effectiveness.

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• 2 years ago - submitted by 涛宣 文

Cassette-based ABL90 FLEX analyzer can deliver 17 parameters from sample as small as 65 μL. ABL90 measures blood gas, electrolytes, metabolites and co-oximetry. The ABL90 analyzer can measure sample from syringe, capillary tube or test tube. Portable, automated analyzer that measures pH, blood gases, electrolytes, glucose, lactate, bilirubin, creatinine.

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• 2 years ago - submitted by Chris Ray

Radiometer blood-gas analyser is intended for in vitro testing of samples of whole blood for the parameters pH, pO2, pCO2, potassium, sodium, calcium, chloride, glucose, lactate, total bilirubin, and co-oximetry parameters (total hemoglobin, oxygen saturation, and the hemoglobin fractions FO 2 Hb, FCOHb, FMetHb, FHHb, FHbF).

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• 2 years ago - submitted by Chris Ray

AI-powered integrated research platform for one-stop analysis of medical images. Provides advanced functionality such as automatic segmentation, registration, and classification for variety of application domains. Has major merits including Advanced built-in algorithms applicable to multiple imaging modalities (i.e., CT, MR, PET, DR), diseases (i.e., tumor, neurodegenerative disease, pneumonia), and applications (i.e., diagnosis, treatment planning, follow-up); Iterative deep learning-based training strategy for fast delineation of ROIs of large-scale datasets, thereby saving clinicians' time and obtaining novel and more robust models; Modular architecture with customization and extensibility, where plugins can be designed for specific purposes.

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• 2 years ago - submitted by [email protected] [email protected]

System for evaluative purposes applies cell stretching and compression force and is operated manually. Has two versions available: 4 cm2 or 10 cm2 stretch chambers. Can mechanically stimulate monolayer and cultured cells and tissue to increase cell growth and shape.

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• 2 years ago - by Anonymous

Software graphical application written in Python, to analyze videos and create notes for events in the video. Used to identify animals’ behaviors based on information extracted from video.

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• 2 years ago - submitted by Chrissy Weber-Schmidt

Instrument provides automated DNA or RNA purification. Sample lysis and binding to paramagnetic particles is primary separation principle. Up to 16 samples can be prepared in single run. Instrument is controlled through graphical user interface running on Tablet PC and has ability to record and report sample tracking and method run data. Reports can be printed and exported to storage location or USB drive.

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• 2 years ago - submitted by Christopher Jenkins

Provides genomic technology services and expertise. Services offered include Nanopore PromethION sequencing, Electronic optical mapping on Nabsys, Optical Genome mapping on Bionano Saphyr, NGS (Illumina-based), Sanger Sequencing, Single cell analysis/RNAseq, Transcriptomic spatial profiling, Gene expression analysis , Droplet Digital PCR & qPCR, Microsatellite/fragment analysis, SNP genotyping , Chromosomal microarray analysis, Sample prep and QC, Project consultation, Bioinformatics support.

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• 2 years ago - submitted by Edyta Vieth

Microplate Reader measures absorbance, fluorescence, time-resolved fluorescence including HTRF, fluorescence polarization, AlphaScreen, AlphaLISA, and luminescence assays for up to 1536-well plates. Detection cartridge modularity allows for easy addition of new read modes within minutes without requiring service visit, while providing flexibility for future applications.

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• 2 years ago - by Anonymous

Software R package for DNA copy number detection from off-target sequence data. Used to extract DNA copy number information from targeted sequencing by utiizing off-target reads.

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• 2 years ago - by Anonymous

Web tool for protein structure prediction, leveraging sequence alignment, template-based modeling, deep learning, and validation techniques. With input of either amino acid sequence or FASTA file, ProStruc generates protein structures. ProStruc automates process of blast searches, template selection, structural modeling, and validation, including RMSD, TM-score, and QMEAN.

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• 2 years ago - by Anonymous

Core assists investigators to identify and quantify proteins and their modifications that are differentially expressed in cells, tissues or body fluids, to track interactions with binding partners during changes in signal transduction, and to identify proteolytic cleavage sites and map post-translational modifications by providing following proteomic services: Consultation, Sample preparation,Protein Identification,Protein Modifications, Protein Quantification, Targeted Quantification, High Resolution Mass Analysis,Training and Self-Service Equipment. Core offers workshops to use the Core’s MALDI-TOF mass spectrometer, Typhoon gel imaging scanner and 2D gel electrophoresis equipment and proteomic software.

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• 2 years ago - by Anonymous

Portal provides access to data set including, for each U.S. census tract (defined using 2010 census tract boundaries), certain social determinants of health data elements, including race/ethnicity, education, poverty, urban/rural, socioeconomic status, and racial residential segregation indices defined using 2008-2012 American Community Survey data and 2010 definitions of rural urban commuting areas.

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• 2 years ago - by Anonymous

Core offers services related to cryo electron microscopy. Services include grid preparation, screening and data collection, as well as user training.

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• 2 years ago - submitted by Edyta Vieth

BIDMC Bioinformatics Core is Unit of the Precision RNA Medicine Core and provides support for management, integration and contextual analysis of biological high-throughput data, training on tools, databases and best practice.

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• 2 years ago - submitted by Edyta Vieth

GetData Graph Digitizer is a program for digitizing graphs and plots. It is often necessary to obtain original (x,y) data from graphs, e.g. from scanned scientific plots, when data values are not available. the URL does not work; the letter sent to the submitter

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• 2 years ago - submitted by Ze Yuan

Collaborative open project of Chan Zuckerberg Initiative and Chan Zuckerberg Biohub. The no-code, cloud-based bioinformatics tool for researchers. Used to analyzing genomic data for free. Hypothesis-free global software platform that helps scientists identify pathogens in metagenomic sequencing data.

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• 2 years ago - submitted by Anita Bandrowski