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Hygromycin B is a broad-spectrum antibiotic primarily used for selective resistance and cell culture. It was originally isolated from the bacterium Streptomyces hygroscopicus. Here are some detailed descriptions of Hygromycin B: Mechanism of Action: Hygromycin B exerts its effects by interfering with bacterial protein synthesis. It binds to the ribosomal subunit, inhibiting the elongation of the peptide chain, which leads to a blockade of protein synthesis. Resistance Mechanism: Some bacteria and eukaryotic cells can develop resistance to Hygromycin B through specific genes (such as the hyg gene), allowing them to survive in environments where the antibiotic is present. Applications: Molecular Biology: Used for selecting cells that express specific resistance genes in transgenic plants and animal cells. Microbiology: Employed to select resistant bacteria for studying specific genetic backgrounds or resistance mechanisms. Cytotoxicity: Although Hygromycin B is widely used in cell culture, it has a certain level of cytotoxicity to mammalian cells, so careful concentration control is necessary when using it. Dosage and Usage: It is typically added to cell culture at specific concentrations (e.g., 50-400 µg/mL), depending on the cell type and experimental design. Overall, Hygromycin B is an important research tool widely used in molecular biology and cell biology.

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• 1 year ago - submitted by Yujing Zhong

MycoAlert detection kit

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• 1 year ago - submitted by Yujing Zhong

antibiotic

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• 1 year ago - submitted by Yujing Zhong

Fetal Bovine Serum

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• 1 year ago - submitted by Yujing Zhong

cell culture medium

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• 1 year ago - submitted by Yujing Zhong

cell culture medium

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• 1 year ago - submitted by Yujing Zhong

Analysis Applications Hybrid Cell Count insufficient information letter sent

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• 1 year ago - submitted by Letizia Amadori

BZ-X800 Analyzer software to analyze and view images acquired with the BZ-X800 microscope.

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• 1 year ago - submitted by Letizia Amadori

A classifier tool based on deep learning methods for the classification and annotation of large-scale fungal ITS sequences.

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• 1 year ago - submitted by kai liu

The Agilent 7250 Series Accurate-Mass Q-TOF is a stand-alone Quadrupole Time-of-Flight (Q-TOF) mass spectrometer coupled with an Agilent 8890 GC.

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• 1 year ago - submitted by Mansa Nair Kihara

The Exploris 240 is a high resolution Orbitrap MS instrument from Thermo with resolution up to 240,000. It is coupled to a Vanquish UPLC system.

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• 1 year ago - submitted by Mansa Nair Kihara

A triple quadrupole mass spectrometer from Waters Corporation couple to an Acquity Premier UPLC system for quantitative analyses.

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• 1 year ago - submitted by Mansa Nair Kihara

The Bruker Impact II is a high resolution quadrupole-time of flight mass spectrometer. It is equipped with a VIP-HESI source and is coupled to an Agilent 1290 UPLC system.

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• 1 year ago - submitted by Mansa Nair Kihara

University of Copenhagen Novo Nordisk Foundation Center for Basic Metabolic Research Metabolomics Platform Core Facility is equipped with a high resolution mass spectrometer with two distinct separation technologies - a second generation dual Trapped Ion Mobility Spectrometry (TIMS) analyzer which provides collision cross section values and Parallel Accumulation Serial Fragmentation (PASEF) which allows downstream selection of precursor ions for fragmentation. The mass spectrometer is coupled with an Agilent 1290 Bio UPLC, with binary solvent pump, multi-sampler and thermostatted column oven. Insufficient Information letter sent. NO picture and description of the instrument on the core page. they have similar instrument already

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• 1 year ago - submitted by Mansa Nair Kihara

The HT7700 is a transmission electron microscope (TEM) by Hitachi, known for its high-resolution imaging capabilities. It provides detailed visualization of internal structures at a sub-nanometer scale, making it ideal for research in materials science, biology, and nanotechnology. The HT7700 offers versatile imaging modes and user-friendly features, enabling both detailed analysis and ease of use for a wide range of samples.

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• 1 year ago - submitted by 涛宣 文

Inositol is a sugar alcohol involved in cellular signaling and metabolism, crucial for insulin sensitivity, lipid metabolism, and neurotransmitter function. The most common form, myo-inositol, is used as a dietary supplement for potential benefits in mental health and managing polycystic ovary syndrome (PCOS). It is naturally present in foods like fruits, beans, grains, and nuts.

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• 1 year ago - submitted by 涛宣 文

Paclitaxel is a chemotherapy medication used to treat a variety of cancers, including ovarian, breast, lung, pancreatic, and other solid tumor cancers. It belongs to a class of drugs known as taxanes, which work by stabilizing microtubules and inhibiting their disassembly, thus disrupting the normal function of the mitotic spindle and preventing cell division. This disruption leads to cell death, particularly in rapidly dividing cancer cells. Paclitaxel is commonly administered intravenously and is often used in combination with other chemotherapy agents to enhance its effectiveness.

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• 1 year ago - submitted by 涛宣 文

GetData Graph Digitizer is a program for digitizing graphs and plots. It is often necessary to obtain original (x,y) data from graphs, e.g. from scanned scientific plots, when data values are not available. the URL does not work; the letter sent to the submitter

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• 1 year ago - submitted by Ze Yuan

BetaActin Taqman Probe (Mouse)- used for quantitative PCR analysis, , #4331182, Mm02619580_g1)

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• 2 years ago - submitted by Tatiana Blanchard

LOXHD1 Taqman Probe (Mouse)- used for quantitative PCR analysis, mouse LOXHD1, #4331182, Mm00555972_m1 )

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• 2 years ago - submitted by Tatiana Blanchard