Curator Dashboard

Facility provides access to instrumentation enabling users to collect data for high-resolution single particle reconstructions and tomographic studies of cells and larger complexes.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Open access multimodal 3D atlases of developing mouse brain that can be used to integrate mouse brain imaging data for visualization, education, cell census mapping, and more. Atlas ages include E11.5, E13.5, E15.5, E18.5, P4, P14, and P56. Web platform can be utilized to visualize and explore the atlas in 3D. Downloadable atlas can be used to align multimodal mouse brain data. Morphologically averaged symmetric template brains serve as the basis reference space and coordinate system. Anatomical labels are manually drawn in 3D based on the prosomeric model. For additional references, the P56 template includes templates and annotations from the aligned Allen Mouse Brain Common Coordinate Framework (Allen CCFv3) and aligned Molecular Atlas of the Adult Mouse Brain.

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• RRID
• 2 years ago - by Anonymous

Software R package to compute various confidence intervals for the Kaplan-Meier estimator, namely: Peto's CI, Rothman CI, CI's based on Greenwood's variance, Thomas and Grunkemeier CI and the simultaneous confidence bands by Nair and Hall and Wellner.

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• RRID
• 2 years ago - by Anonymous

Software R package as collection of functions to compute the Clopper-Pearson Confidence Interval and the required sample size. Density, distribution function, quantile function and random generation for the Generalized Binomial Distribution.Enhanced model for burn-in studies, where failures are tackled by countermeasures.

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• RRID
• 2 years ago - by Anonymous

Core facilities pre-clinical studies of orthopedic devices intended for animal and human use, clinical studies of treatment and prevention of respiratory diseases in horses and animal clinical trials evaluating the treatment of bladder cancer in Scottish Terriers, an animal model of human bladder cancer.

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• RRID
• 2 years ago - submitted by Edyta Vieth

Mechanisms of Behavior Core offers the equipment, reagents, bench space, and expertise to answer questions related to the roles of genetics and hormones in relation to animal behavior.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core provides drug and metabolite concentrations from a variety of biological matrices such as (but not limited to): plasma, urine, CSF, and tissue using HPLC-MS/MS. Additional services include protein binding of drugs, formulation studies, drug stability, drug metabolism, and metabolite screening.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides numerous types of mass-spectrometry based proteomics services, including global proteome quantitation, affinity purification-mass spectrometry, targeted mass spectrometry analysis for precise quantitation, post-translational modification analysis, and a variety of consulting services.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides access to large chemical and CRISPR libraries and state-of-the-art instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility also provides assistance in assay development

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

CRC houses two complementary resources: the High-Performance Computing section, providing over 35,000 cores of computational power with the associated support infrastructure for both hardware and installed software, and the Cyberinfrastructure section, empowering Faculty and industry partners to develop research software and environments that support advanced data and information processing services including acquisition, storage, management, integration, mining

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. The ABC also manages an IncuCyte Zoom and Seahorse XFp.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides high-throughput genomics services including: genomic DNA sequencing, transcriptome RNA sequencing, miRNA sequencing, methylome or targeted methylation sequencing, protein DNA/RNA interaction (ChIP-seq, ATAC-seq and CLIP-seq), 10x single cell or single nuclei sequencing, and SNP genotyping.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Nanofabrication cleanroom, bio-pharma clean room, nanometrology laboratories, nanomanufacturing laboratories, microelectronics and microfuidics fabrication and testing laboratories, 3D cell culture and tissue chip laboratories.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core collaborates with investigators through all phases of cell and gene therapy manufacturing, from pre-clinical design through treatment of patients. Facility comprises the Cell Immunotherapy and Transduction Facility (CIT), the Vector Production Facility (VPF), and the Bioprocess Development and Cell Manufacturing Lab (BDL).

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Provides study design and data analysis for health-related research, including grant or protocol development, sample size and power calculations, data management, data analysis, and scientific writing. Support can range from hourly support on a short-term project to including a biostatistician on a long-term grant collaboration.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core offers services related to biospecimen and data collection in support of cancer research. Provides collection of well-annotated samples from patients with malignancy and normal controls to support studies exploring the biologic basis of cancer, move basic findings to clinic, and probe the biology underlying clinical and population phenomena.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core performs highly customizable efficacy testing of novel drug or therapies for antitumor activity. We also acquire blood or tissues for pharmacokinetic or pharmacodynamic analyses.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets. Core offers services including Next Generation Sequence Data Analysis; Microarray Data Analysis; Proteomics Data Analysis;Multi-omics Data Integration;Statistical Genetics;Pharmacokinetics/Pharmacodynamics Data Analysis; Drug Absorption, Disposition, Metabolism, Elimination and Transportation Prediction, and Drug Exposure Prediction;Public Domain Database Access and Custom Data Annotation.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Core consists of the Specimen Storage Facility (SSF) and the Clinical and Translational Support Laboratory (CTSL), which together offer cost efficient sample processing and storage services with focus on consistent quality and sample integrity.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth