Curator Dashboard

Software package for flexible spatial reconstruction of single-cell gene expression with optimal transport. Framework for de novo spatial reconstruction of single-cell gene expression. Assigns cells to tissue locations using probabilistic/optimal-transport models, with or without prior marker information, and returns spatial maps and assignment probabilities.

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• RRID
• 1 year ago - submitted by 程斐 廉

It provides access to results from RNAi interference studies in C. elegans, including images, movies, phenotypes, and graphical maps. RNAiDB contains all published RNAi experiments in C. elegans that have been deposited in WormBase, including data from the literature and published large-scale RNAi studies. RNAi to gene mappings for all experiments have been re-analyzed using ePCR and/or a sliding n-mer window method to identify all genes in different genomic locations that may potentially be inhibited by each experiment. Gene maps showing canonical and putative alternate mappings are displayed graphically on RNAi Experiment and Gene/ORF card pages.

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• SciCrunch
• 17 years ago - by Anonymous

Open software pipeline for analyzing RNA-seq to predict neoepitopes derived from small to large sized indels. Used for identifying indel derived neoantigens using RNA-Seq data.

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• RRID-Legacy
• 6 years ago - submitted by Tingyou Wang

Software R package for Bounded Memory Linear and Generalized Linear Models. Regression for data too large to fit in memory.

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• SciCrunch
• 11 months ago - by Anonymous

BrainWeb provides information and links to validated sites about brain diseases and disorders. These include outside resources reviewed by scientific advisers, as well as articles in Dana publications. Sites listed in BrainWeb detail common brain diseases and disorders, and include general neuroscience and health resources. They offer descriptions of conditions, frequently asked questions, organization contacts, and sources for more information. BrainWeb and its links are suitable for lay readers, including students and educators, as well as people with brain disorders, their families, and caregivers.

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• SciCrunch
• 14 years ago - by Anonymous

CSIRO, the Commonwealth Scientific and Industrial Research Organisation, is Australia''s national science agency and one of the largest and most diverse research agencies in the world. National Research Flagships: Large-scale, long-term, multidisciplinary science to address Australia''s major national challenges and opportunities. Divisions: CSIRO expertise is organised into 14 research areas: * Animal, Food and Health Sciences * Astronomy and Space Science * Earth Science and Resource Engineering * Ecosystem Sciences * Energy Technology * Food & Nutritional Sciences * ICT Centre * Land and Water * Livestock Industries * Marine and Atmospheric Research * Materials Science & Engineering * Mathematics, Informatics and Statistics * Plant Industry * Process Science and Engineering National Facilities: CSIRO manages national facilities and collections that are opened to researchers around Australia and overseas.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Portuguese national research infrastructure which provides expert consultation for the safe and effective use of vector technologies, and offers custom design and production services for multiple viral types to the national research community and other stakeholders.

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• RRID
• 11 months ago - submitted by Edyta Vieth

A portal to the Mouse Atlas of Gene Expression Project and Dissecting Gene Expression Networks in Mammalian Organogenesis Project. This Atlas will define the normal state for many tissues by determining, in a comprehensive and quantitative fashion, the number and identity of genes expressed throughout development. The resource will be comprehensive, quantitative, and publicly accessible, containing data on essentially all genes expressed throughout select stages of mouse development. Serial Analysis of Gene Expression (SAGE) is the gene expression methodology of choice for this work. Unlike expressed sequence tags (ESTs) and gene chip data, SAGE data are independent of prior gene discovery and are quantitative. Furthermore, SAGE data are digital, easily exchanged between laboratories for comparison and can be added to by scientists for years to come. Thus, this Atlas will include a data structure and data curation strategy that will facilitate the ongoing collection of gene expression data, even after the completion of this project. The Mouse Atlas project compromises 202 SAGE Libraries from 198 tissues. The list of libraries is available in a number of different groupings, including groups of libraries taken from specific tissue locations and libraries taken from specific developmental stages. Furthermore, this atlas will assemble gene expression profiles for a few focused experiments that will test hypotheses related to the techniques employed, tumor models and models of abnormal development. This will test the resource and provide quality control, validation and demonstrate applicability. Additionally, The Mammalian Organogenesis - Regulation by Gene Expression Networks (MORGEN) project will provide a complete, permanent, and accurate picture of mouse gene expression in the heart (atrioventricular canal and outflow tract), pancreas, and liver; new techniques to understand the interplay of proteins governing the expression of genes key to the development of these organ systems; and the identification of the master regulatory switches that control development of the tissues.

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• SciCrunch
• 17 years ago - by Anonymous

The Friedrich Miescher Institute is devoted to fundamental biomedical research aimed at understanding the basic molecular mechanisms of health and disease. We communicate and patent our findings to enable their translation into medical application. The FMI focuses on the fields of Epigenetics, Signaling & Cancer, and Neurobiology. In these fields, the FMI has gained international recognition as a center of excellence in innovative biomedical research. Training young scientists The Friedrich Miescher Institute contributes to the training of graduate students and postdoctoral fellows. Through its PhD program, which was established as early as 1970, the FMI attracts top international students. The FMI is affiliated with the University of Basel, where most of the graduate students are enrolled and where it contributes to the teaching program. Many FMI alumni have gone on to pursue successful careers in Novartis, in other pharmaceutical companies, or in academic research. Exciting environment for academic and applied research Staff at FMI benefit from a unique scientific environment, allowing researchers, specialists and students to pursue questions that yield new scientific insights. As part of the Novartis Research Foundation, the FMI receives strong core support from the foundation. Funding is supplemented by competitive fellowships and awards from national and international funding agencies. This provides an optimal environment for both academic and applied biomedical research.

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• SciCrunch
• 16 years ago - by Anonymous

Core provides VisualSonics Vevo 3100 high-frequency ultrasound imaging unit, small animal imaging station, micro-injection system, anesthesia unit; Linear array transducers (MX250, MX550D, MX700); VevoLab use.

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• RRID
• 11 months ago - by Anonymous

THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 26, 2016. The BIODEF database have tabulated the most common clinical and laboratory data related to hyperphenylalaninaemia and tetrahydrobiopterin deficiencies. Additionally, there are data regarding treatment, outcome, and DNA analysis. Approximately 2% of newborns with hyperphenylalaninaemia are deficient in tetrahydrobiopterin. Selective screening must be performed in all instances where hyperphenylalaninaemia is detected by neonatal screening. In the last 20 years, 308 patients with tetrahydrobiopterin deficiencies have been recognized as a result of screening carried out, worldwide, in Departments of Paediatrics. Of these 308 patients, 181 suffered from 6-pyruvoyltetrahydropterin synthase deficiency, 92 from dihydropteridine reductase deficiency, 13 from pterin-4a-carbinolamine dehydratase deficiency, 12 from GTP cyclohydrolase I deficiency, and 10 are still unclassified. The BIODEF database have tabulated the most common clinical and laboratory data related to hyperphenylalaninaemia and tetrahydrobiopterin deficiencies. Additionally, there are data regarding treatment, outcome, and DNA analysis. Preliminary evaluation reveals that the degree of hyperphenylalaninaemia can vary from normal to 2500 mumol/L. Analyses of pterins in urine and measurement of dihydropteridine reductase activity from Guthrie cards are absolutely essential tests for accurate diagnosis. There is a regional (demographic) variation in the frequency of tetrahydrobiopterin deficiencies indicating the highest incidence in Saudi Arabia, probably a consequence of the high consanguinity rate.

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• SciCrunch
• 17 years ago - by Anonymous

Georgia Institute of Technology, commonly referred to as Georgia Tech or, in the state of Georgia, as Tech, is a public research university and institute of technology in Atlanta, Georgia.

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• SciCrunch
• 17 years ago - submitted by Stephen Larson

Core offers services including statistical analyses, grant applications, prep for manuscript publications, etc.

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• RRID
• 10 months ago - by Anonymous

A software development competition, the DIADEM Challenge,to benefit the scientific community by encouraging the development of better software for automating three-dimensional reconstructions of neuronal arbors. The intent of the Sponsors is to ensure that the best software submitted for the competition is made available to the scientific community within a reasonable time and on reasonable terms. No purchase is necessary to enter or win. The competition will have two rounds. As of April 10, 2009, individuals and teams may register to participate in the competition and may download sets of image stacks (Data Sets) of non-human animal brains along with three-dimensional reconstructions for some of these Data Sets for training purposes. Submissions of software, including executable programs, supporting documentation, and reconstruction files for the Data Sets, must be uploaded to the competition website no later than April 9, 2010. In order to be eligible to win the competition, the individuals and at least one member of any teams whose submissions are selected for the Final Round (Finalists) must participate in the Final Round and scientific conference. Personal participation in the Final Round and scientific conference is important for two main reasons: first, because the Finalists software will be tested at the Final Round against additional Data Sets so that the judges can select a winner or winners, and second, because the larger scientific conference, of which the Final Round will be a part, is intended to foster extensive scientific interaction among neuroscientists and computational scientists, including plenary and poster sessions to discuss challenges, solutions, and future directions. There are 5 datasets, all of which have to be reconstructed for the qualifier phase. Once you have registered your group, dataset download information will be sent to you via E-mail. The 5 datasets are: - Cerebellar Climbing Fibers - Hippocampal CA3 Interneuron - Neocortical Layer 6 Axons - Neuromuscular Projection Fibers - Olfactory Projection Fibers Sponsors: The sponsors of this competition are: Allen Institute for Brain Science, Seattle, Washington; Howard Hughes Medical Institute (HHMI), Chevy Chase, Maryland; and Krasnow Institute for Advanced Study, George Mason University, Fairfax, Virginia.

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• SciCrunch
• 17 years ago - by Anonymous

Multi-disciplinary research organization with strengths in crops, soils, land & environmental research, studying food, energy & environmental sustainability in Aberdeen and Dundee, UK. The James Hutton Institute brings together the Macaulay Land Use Research Institute and SCRI (Scottish Crop Research Institute) both of which have illustrious histories. The new institute was created on 1 April 2011. The new organization will make major, new contributions to the understanding of key global issues, such as food, energy and environmental security, and developing and promoting effective technological and management solutions to these. The James Hutton Institute is an internationally networked organization and operates from multiple sites, including two main ones in Scotland at Aberdeen and Dundee. It employs more than 600 scientists and support staff, making it one of the biggest research centers in the UK and the first of its type in Europe. The institute is one of the Scottish Government''s main research providers in environmental, crop and food science and will have a major role in the Scottish knowledge economy. James Hutton (1726 1797) was a leading figure of the Scottish Enlightenment, an eighteenth century golden age of intellectual and scientific achievements centered on Edinburgh. He is internationally regarded as the founder of modern geology and one of the first scientists to describe the Earth as a living system. His thinking on natural selection influenced Charles Darwin in developing his theory of evolution.

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• SciCrunch
• 15 years ago - submitted by Andrea Stagg

Facility for Imaging and Brain Research houses 3T Siemens Prisma scanner, mock scanner, and data analysis facilities. Research dedicated MRI scanning facility designed to suit wide range of basic and translational research programs by researchers across the UCI campus and beyond.

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• RRID
• 10 months ago - submitted by Zhiqun Tan

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 12,2023. An integrated packages of tools for microarray data analysis. GEPAS provides a web-based interface that offers diverse analysis options from the early step of preprocessing (normalization of Affymetrix and two-color microarray experiments and other preprocessing options), to the final step of the functional profiling of the experiment (using Gene Ontology, pathways, PubMed abstracts etc.), which include different possibilities for clustering, gene selection, class prediction and array-comparative genomic hybridization management.

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• SciCrunch
• 17 years ago - by Anonymous

Ministry of the Government of Singapore that directs the formulation and implementation of policies related to Education in Singapore.

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• SciCrunch
• 16 years ago - submitted by Andrea Stagg

Core functions include cancer biology, medicine, chemistry, physics, radiochemistry, pharmacology, and engineering.Provides investigators with radionuclides and to incorporate these radionuclides into radiolabeled diagnostic and/or therapeutic pharmaceuticals for both basic research investigations and patient formulations. Core provides services: Cyclotron Radionuclide Production Section, Radiolabeling Section, Development and Clinical Translation Section, and Hyperpolarized Magnetic Resonance Section.

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• RRID
• 10 months ago - submitted by Patrick Badua

Software tool as Program for Comparative Protein Structure Modelling by Satisfaction of Spatial Restraints. Used for homology or comparative modeling of protein three dimensional structures. User provides alignment of sequence to be modeled with known related structures and MODELLER automatically calculates model containing all non hydrogen atoms.

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• SciCrunch
• 17 years ago - by Anonymous