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Hygromycin B is a broad-spectrum antibiotic primarily used for selective resistance and cell culture. It was originally isolated from the bacterium Streptomyces hygroscopicus. Here are some detailed descriptions of Hygromycin B: Mechanism of Action: Hygromycin B exerts its effects by interfering with bacterial protein synthesis. It binds to the ribosomal subunit, inhibiting the elongation of the peptide chain, which leads to a blockade of protein synthesis. Resistance Mechanism: Some bacteria and eukaryotic cells can develop resistance to Hygromycin B through specific genes (such as the hyg gene), allowing them to survive in environments where the antibiotic is present. Applications: Molecular Biology: Used for selecting cells that express specific resistance genes in transgenic plants and animal cells. Microbiology: Employed to select resistant bacteria for studying specific genetic backgrounds or resistance mechanisms. Cytotoxicity: Although Hygromycin B is widely used in cell culture, it has a certain level of cytotoxicity to mammalian cells, so careful concentration control is necessary when using it. Dosage and Usage: It is typically added to cell culture at specific concentrations (e.g., 50-400 µg/mL), depending on the cell type and experimental design. Overall, Hygromycin B is an important research tool widely used in molecular biology and cell biology.

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• 1 year ago - submitted by Yujing Zhong

MycoAlert detection kit

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• 1 year ago - submitted by Yujing Zhong

antibiotic

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• 1 year ago - submitted by Yujing Zhong

Fetal Bovine Serum

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• 1 year ago - submitted by Yujing Zhong

cell culture medium

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• 1 year ago - submitted by Yujing Zhong

cell culture medium

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• 1 year ago - submitted by Yujing Zhong

Web server that integrated data visualization and graphing functions together. Can be run easily with all Web browsers, with user-friendly graphical interface, users can paste your data directly into input box according to defined file format. Resulting graphs can be downloaded in bitmap (PNG or TIFF) or vector (PDF or SVG) format in publication quality. Used for data visualization and graphing.

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• 1 year ago - by Anonymous

Software tool for differential cell-cell communication analysis from multi-sample multi-condition single-cell transcriptomics data.

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• 1 year ago - by Anonymous

Data about Alabama, Maryland, Missouri and Connecticut people and economy.

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• 1 year ago - by Anonymous

Provides services for data analysis, pipeline management, and artificial intelligence research and operations. Data types analysed by the core include whole-genome and whole-exome sequencing, targeted re-sequencing, radiological images, RNA-sequencing, single-cell RNA sequencing, ChIP-sequencing, NanoString and various types of microarray data. Core also develops and maintains software infrastructure required for bioinformatics processing, including pipelines and cloud provision systems.

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• 1 year ago - submitted by Edyta Vieth

Siemens Biograph mMR represents major technological breakthrough in imaging field by combining positron emission tomography (PET) and magnetic resonance imaging (MRI) in one scanner. This system allows simultaneous acquisition of MR and PET images in human subjects.

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• 2 years ago - submitted by Letizia Amadori

System composed of DNBseq PE150 sequencing platform for RNA sequencing transcriptome with BGISEQ-500 desktop sequencer which uses DNA nanoball and combinational probe anchor synthesis developed from Complete Genomics sequencing technologies to generate short reads at large scale. DNBseq PE150 sequencing platform uses DNA nanoballs that are loaded onto flow cells and then read using fluorescent probes. The platform then uses lasers to excite the probes and take millions of images to identify bases.

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• 2 years ago - submitted by Letizia Amadori

Analysis Applications Hybrid Cell Count insufficient information letter sent

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• 2 years ago - submitted by Letizia Amadori

BZ-X800 Analyzer software to analyze and view images acquired with the BZ-X800 microscope.

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• 2 years ago - submitted by Letizia Amadori

Registry for describing, sharing and publishing scientific computational workflows. Aims to facilitate discovery and re-use of workflows in accessible and interoperable way. This is achieved through extensive use of open standards and tools, including CWL, RO-Crate, Bioschemas and GA4GH's TRS API, in accordance with FAIR principles.WorkflowHub supports workflows of any type in its native repository.

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• 2 years ago - submitted by Anita Bandrowski

Core is equipped with protein separation and mass spectrometry equipment as well as trained personnel to perform comparative analyses of complex protein mixtures and to identify differentially-expressed proteins. Offers guidance and consultation.

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• 2 years ago - submitted by Edyta Vieth

Offers high-throughput sequencing and genotyping services utilizing cutting edge Illumina and Xoford Nanopore systems. Sequencing facility in Oklahoma. Equipped with an Illumina NovaSeq 6000, Illumina NextSeq 2000, Illumina MiSeq, Illumina iSeq, Oxford Nanopore PromethION 2, and Oxford Nanopore MinION,Illumina iScan and Autoloader for extremely-high throughput genotyping projects. Core can perform all aspects of NGS, ranging from whole genome sequencing to single-cell transcriptomics.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Mass spectrometry based proteomics.

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• 2 years ago - submitted by Edyta Vieth

Facility houses 13 high-end light microscopes including point scanning and spinning disk confocals, Airyscan, 3D-STED super resolution, widefield and TIRF systems. Core offers training, consultation and access to powerful analysis computers with licensed softwares.

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• SciCrunch
• 2 years ago - submitted by Edyta Vieth

Light and fluorescence microscopy core facility with Zeiss, Nikon, 3I, Leica and Olympus Microscopes. Distributed light microscopy core facility consisting of inverted and upright confocal microscopes (laser scanning and spinning disk) some with superresolution, atomic force microscopy, total internal fluorescence reflection (TIRF), high throughput multicolor imaging of fixed tissue sections or cells on slides, and live cell imaging in most modalities.

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• 2 years ago - by Anonymous