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Instrument screens thermal hyperalgesia and allodynia,conditions often observed in patients with neuropathic pain or inflammation. Also used for testing analgesic and anti-inflammatory drugs. Plate test includes all the latest technologies necessary to run constant temperature, linear ramping temperature (toward hot or toward cold) and complex temperature ramps thanks to the included X-Pad software.New model includes keypad (cabled or optional Bluetooth) to score pain endpoints or stereotyped behaviors. Temperature range goes from -5° to 65°C and animal holders of different heights are available.
Semmes-Weinstein Von Frey Aesthesiometer for touch assessment. The Semmes-Weinstein monofilaments provide an approximate logarithmic scale of actual force, and a linear scale of perceived intensity. They have a long history of effective use in clinical settings, and can be used to diagnose pathologies of hyper- or hypo-aesthesia. Subsets within the set of 20 probes distinguish pathologies on different parts of the body (foot, hand, lip, cheek,etc.).
Compact reader for analysis of up to 50 analytes in single sample.Designed to read assays developed on magnetic xMap (MagPlex) beads and comes with Bio-Plex Manager analysis software. Bio-Plex MAGPIX Multiplex Reader is now discontinued. Bio-Rad will continue to provide premium Luminex instrumentation: the Bio-Plex® 200 System and Bio-Plex® 3D Suspension Array System and service, support, accessories, and software for customers with the Bio-Plex MAGPIX Multiplex Reader.
Software R tool designed for single-sample mutation-based pathway analysis by integrating somatic mutation data with protein-protein interaction (PPI) networks.
Searchable catalog of enhancer-adeno-associated viruses (AAVs) that have been developed and tested at the Allen Institute for Brain Science. We present a suite of enhancer AAVs that can provide access to specific cell types when delivered to the whole brain. Multiple epigenomic and transcriptomic datasets were interrogated to reveal candidate enhancers that are selectively accessible in particular cell populations. Enhancer AAVs were constructed and screened for desirable expression and a sizeable subset of enhancer AAVs were subjected to further characterization by single cell transcriptomics and/or brain-wide expression imaging in mouse. In the GTA, we present a large toolkit for selective gene expression in cell types of interest. Genetic Tools Atlas is part of the growing Brain Knowledge Platform.
Software algorithm for fully automatic image stitching of volume electron microscopy.Used to stitch input biological tiles while correcting local distortion.
Portal provides information about available datasets, resources, tools, and services related to pandemic preparedness in Norway. Portal gives researchers, clinicians and policymakers access to collection of biomolecular data about pathogens.
Software genetic expression and variation data visualization tool for neurological diseases biomarkers.
Bruker timsTOF Ultra boasts increased sensitivity and resolution whilst allowing for exceptionally low sample input and resolution whilst allowing for exceptionally low sample input.
Software Python package for computing corrected test statistics for comparing machine learning models on correlated samples. Software package version of correctR.
Software tool as modified R ks.test to obtain sign and force exact p-value.
Sapphire FL is second generation Sapphire and ultimate biomolecular imager for FLEXIBILITY. With customizable and user-changeable laser and filter modules. Offers customizable and user changeable optical modules, 5–1000 μm resolution scans, Z-plane range from -1.0 to +6 mm, 5 anesthesia ports for imaging living animals, chemiluminescence detection through Chemiluminescence Module.
Core offers services from experimental design and sample preparation to instrumentation, data analysis, interpretation, and validation. Provides sequencing technologies and team of well trained staff.
Software tool for testing whether specified covariate influences membership of single cells in any of multiple cellular subsets while accounting for technical confounds and biological variation.
Transcription factor target database. Platform consolidating both computationally predicted and experimentally validated binding sites between transfer RNA-derived fragments and target genes or transcripts across multiple organisms.
Software R package implementation of Milo for testing for differential abundance in k-nearest neighbor graphs. Milo can identify perturbations that are obscured by discretizing cells into clusters. Used for differential abundance analysis on KNN graph from single-cell datasets.
Biotechnology company in Baltimore, Maryland, specializing in liquid biopsy. Offers comprehensive NGS testing services for clinical trials, enhancing oncology drug development and patient outcomes.
American company based in Cambridge, Massachusetts, which develops, manufactures, and sells genomic profiling assays based on next-generation sequencing technology for solid tumors, hematologic malignancies, and sarcomas. Specializes in precision medicine. FMI routinely analyzes cancer specimens using advanced sequencing technology of FoundationOne to profile tumor genomics.
System features multi-component IonDrive technology including IonDrive High Energy Detector+ to enable to see low mass to high mass compounds, in positive or negative polarity in single injection.