We support boolean queries, use +,-,<,>,~,* to alter the weighting of terms
Database of quality assessed protein-protein interactions in nine species.
Software program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel.
Portal showcases, aggregates, and facilitates the visualisation of non-human eukaryotic genome assemblies and genome annotations for species studied by Swedish research community, aiming to foster collaboration, highlight researchers’ work, and promote open science and FAIR data sharing.
Disodium clodronate is a selective macrophage-killing agent that removes macrophages from tissues by inducing apoptosis. Currently, the ideal reagent on the market for efficient macrophage depletion is disodium clodronate liposomes. The clodronate molecules are encapsulated within liposomal vesicles, offering high activity, enhanced stability, and ease of use. Intravenous injection of 0.2 mL clodronate liposomes can achieve an 80-90% clearance rate of macrophages in the spleen (red pulp macrophages) within 24 hours. A version of this product without disodium clodronate is also available, with the liposomes containing only PBS, which can be used as a control in experiments to determine if macrophage depletion is specifically due to the effects of clodronate liposome injection.
Clodronate Liposomes were developed by Professor Nico van Rooijen at Vrije University Amsterdam, Netherlands. They utilize the phagocytic mechanism of macrophages to deliver the membrane-impermeable clodronate into cells. Within macrophages, clodronate dissolved in the aqueous phase of the liposomes is released under the action of lysosomal phosphatases and accumulates inside the cell. When clodronate reaches a certain concentration, it induces apoptosis in macrophages, thereby achieving the goal of macrophage depletion. Clodronate Liposomes are suitable for various injection routes, including intravenous, intraperitoneal, subcutaneous, intranasal, and testicular injections. The injection dosage depends on the mouse’s body weight, injection schedule, route of administration, and the specific experimental objectives.
Software provides direct mapping refence between expanded molecular alphabet and N-nary digits in the absence of high-performance transcoding algorithm at present. Transcoding scheme for DNA data storage based on expanded molecular alphabet.
Zombie Aqua™ is an amine-reactive fluorescent dye that is non-permeant to live cells but permeant to cells with compromised membranes. Thus, it can be used to assess live vs. dead status of mammalian cells. Zombie Aqua™ is a polar, water-soluble dye providing very bright green fluorescence, making it suitable for use in multi-color detection.
The Thermo Scientific PageRuler Prestained Protein Ladder is a protein size marker for SDS-PAGE and Western blotting, consisting of a mixture of ten proteins (10 to 180 kDa) that are prestained in blue, orange, and green. The protein ladder is provided in a ready-to-use format and can be directly loaded onto gels without the need for heating, reduction, or the addition of sample buffer prior to use.
Inverted microscope designed for advanced microscopy applications. Allows for observing samples from below, making it ideal for examining living cells and tissue cultures.Includes fluorescence, phase contrast, and differential interference contrast imaging. Can be upgraded to use modern digital camera systems through the side port or one of the two eyepiece tubes.
Analyzer allows detection and assessment of changes in glaucoma progression using mixed SITA tests taken on any HFA instrument.
ZEISS CIRRUS 5000 non-invasive OCT angiography (OCTA) technology, you can confidently visualize retinal microvasculature and monitor change over time.
First digital broadband MR system. MRI scanner samples the Magnetic Resonance signal directly in the coil on the patient, and sends it to the reconstructor via fiber-optic cable. Enables imaging with fewer coils and reduce patient set up time.
recombinant murine MSLN protein produced by Novoprotein
Core offers bioinformatics consultation, training, and data analysis to help investigators analyze and understand large-scale biological datasets required from different platforms, including next generation sequencing, array-based technologies and mass spectrometry. Provides development and operation of standard and advanced data processing pipelines, covering tasks such as bulk next-generation sequencing analysis (e.g., RNA-Seq, DNA-Seq, methyl-Seq, and ChIP-Seq), single-cell analysis, transcriptome and genome annotation, variant detection and interpretation and metagenomics. Our team members have extensive experience in bioinformatics, biostatistics, genomics, genetics, transcriptomics and translational informatics in human, animal and microbial systems. Our expertise includes big data analysis, statistical analysis, machine learning, neuro network, software development and high-performance computing. Our approach prioritizes scientific collaboration, going beyond mere service provision to leverage our skills and knowledge for the success of your projects. Offers support for grant applications, including key personnel involvement, support letters, and analytical method write-ups.
Biotechnology company focused on pioneering cancer basic research services. Provides early discovery and development of preclinical studies. Offers services range from genetic analysis, tumor biology research, and biomarker validation, to comprehensive cancer model customization services.
Based at the Douglas Research Centre, the Douglas Brain Bank (DBB) houses a large collection of brains from people with diverse psychiatric disorders, including schizophrenia, major depression, bipolar disorder and substance use disorders, as well as brains from individuals with various neurological and developmental disorders such as amyotrophic lateral sclerosis (ALS), Alzheimers disease and autism spectrum disorder (ASD). In addition, the DBCBB manages a large relational database containing demographic, clinical and developmental histories from donors.