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Mass spectrometry based proteomics.
Facility houses 13 high-end light microscopes including point scanning and spinning disk confocals, Airyscan, 3D-STED super resolution, widefield and TIRF systems. Core offers training, consultation and access to powerful analysis computers with licensed softwares.
Light and fluorescence microscopy core facility with Zeiss, Nikon, 3I, Leica and Olympus Microscopes. Distributed light microscopy core facility consisting of inverted and upright confocal microscopes (laser scanning and spinning disk) some with superresolution, atomic force microscopy, total internal fluorescence reflection (TIRF), high throughput multicolor imaging of fixed tissue sections or cells on slides, and live cell imaging in most modalities.
Agilent NovoCyte 3000 Flow Cytometer with 3 lasers (488, 405, 640 nm) and up 13 colors. 6 colors from violet laser; 5 colors from blue laser; 2 colors from red laser. NovoExpress software used for acquisition.
Provide Rockefeller University researchers and collaborators with infrastructure necessary for computationally intensive workloads, as well as training and support for using these resources.
Software Python package for external validation of machine learning models with adaptive sample splitting.
Software classifier tool based on deep learning methods for classification and annotation of large-scale fungal ITS sequences. Used for fungal species classification.
Web-service that can generate highly accurate biomolecular structure predictions containing proteins, DNA, RNA, ligands, ions, and also model chemical modifications for proteins and nucleic acids in one platform. Powered by AlphaFold 3 model.
SMARTER-database aims to collect data produced by SMAll RuminanTs breeding for Efficiency and Resilience project and to merge them with already available genotype data. Used to explore genomic diversity in small ruminants.
Software tool as Oxford Nanopore basecaller. Used to determine nucleotide sequence.
Software suite based on BlobTools to aid researchers in identifying and isolating non-target data in draft and publicly available genome assemblies. Used for genome assembly QC and contaminant cobiont detection and filtering. Can be used to process assembly, read and analysis files for fully reproducible interactive exploration in the browser-based Viewer. Can be used during assembly to filter non-target DNA. BlobToolKit is comprised of four distinct components: BlobTools2 (command line tools to create and filter datasets), Specification (a formal specification and validator for the JSON-based data format), Viewer (interactive dataset visualization), and INSDC-pipeline (a Snakemake pipeline to run the BlobToolKit workflow on publicly available datasets).
AMI Imaging Center houses advanced, commercial light microscopes. These instruments are tailored for use in the life sciences and provide high spatial and temporal resolution to study variety of biology.
Cassette-based ABL90 FLEX analyzer can deliver 17 parameters from sample as small as 65 μL. ABL90 measures blood gas, electrolytes, metabolites and co-oximetry. The ABL90 analyzer can measure sample from syringe, capillary tube or test tube. Portable, automated analyzer that measures pH, blood gases, electrolytes, glucose, lactate, bilirubin, creatinine.
Radiometer blood-gas analyser is intended for in vitro testing of samples of whole blood for the parameters pH, pO2, pCO2, potassium, sodium, calcium, chloride, glucose, lactate, total bilirubin, and co-oximetry parameters (total hemoglobin, oxygen saturation, and the hemoglobin fractions FO 2 Hb, FCOHb, FMetHb, FHHb, FHbF).
AI-powered integrated research platform for one-stop analysis of medical images. Provides advanced functionality such as automatic segmentation, registration, and classification for variety of application domains. Has major merits including Advanced built-in algorithms applicable to multiple imaging modalities (i.e., CT, MR, PET, DR), diseases (i.e., tumor, neurodegenerative disease, pneumonia), and applications (i.e., diagnosis, treatment planning, follow-up); Iterative deep learning-based training strategy for fast delineation of ROIs of large-scale datasets, thereby saving clinicians' time and obtaining novel and more robust models; Modular architecture with customization and extensibility, where plugins can be designed for specific purposes.
System for evaluative purposes applies cell stretching and compression force and is operated manually. Has two versions available: 4 cm2 or 10 cm2 stretch chambers. Can mechanically stimulate monolayer and cultured cells and tissue to increase cell growth and shape.
Software graphical application written in Python, to analyze videos and create notes for events in the video. Used to identify animals’ behaviors based on information extracted from video.
Instrument provides automated DNA or RNA purification. Sample lysis and binding to paramagnetic particles is primary separation principle. Up to 16 samples can be prepared in single run. Instrument is controlled through graphical user interface running on Tablet PC and has ability to record and report sample tracking and method run data. Reports can be printed and exported to storage location or USB drive.
Provides genomic technology services and expertise. Services offered include Nanopore PromethION sequencing, Electronic optical mapping on Nabsys, Optical Genome mapping on Bionano Saphyr, NGS (Illumina-based), Sanger Sequencing, Single cell analysis/RNAseq, Transcriptomic spatial profiling, Gene expression analysis , Droplet Digital PCR & qPCR, Microsatellite/fragment analysis, SNP genotyping , Chromosomal microarray analysis, Sample prep and QC, Project consultation, Bioinformatics support.
Microplate Reader measures absorbance, fluorescence, time-resolved fluorescence including HTRF, fluorescence polarization, AlphaScreen, AlphaLISA, and luminescence assays for up to 1536-well plates. Detection cartridge modularity allows for easy addition of new read modes within minutes without requiring service visit, while providing flexibility for future applications.