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Core provides open access availability to NMR spectroscopy instrumentation, training and sample preparation. Facility can be accessed individually or as full service center. NMR Facility has a total space of ~2,500 sq ft. divided among 3 rooms fully constructed with considerations for cooling, in-place floor dampening infrastructure and space for wet lab/sample preparation. Facility specializes in small molecule structure determination, small molecule characterization, biomolecular/protein structure determination, qualitative and quantitative NMR analysis, and small molecule purification from wide variety of sample sources.
Micro and nanofabrication facility that offers range of processing and packaging capabilities including lithography, wet and dry etching, thin film deposition, dicing, wire bonding, metrology, and inspection.
Provides equipment and team support to the workflow of all things geo-spatial from primary data collection using suite of different sensors and platforms to analysis that includes:Advanced mapping and geo-spatial analysis that leverage Uncrewed Aerial Vehicle (UAV) or drone-based sensors that use LiDAR, hyperspectral, thermal, orthoimagery, and Structure from Motion; High precision mapping and analysis using GPS and GNSS; Acoustic Doppler Profiles of rivers, reservoirs, and lakes;Data visualization and cartography;Remote sensing using active and passive sensors;Geo-spatial analysis, data development, and management;High Performance Computing infrastructure that leverages all of the above using open source and proprietary software.
System to capture images and analyze data from western blots and gels. Supports main imaging applications of fluorescent, chemiluminescent, and colorimetric western blots, in addition to fluorescent stained nucleic acid gels, fluorescent stained protein gels, colorimetric stained protein gels, and colorimetric membrane stains.
Multi-mode microplate reader that measures chemical, biological, and physical reactions in microplates. It comes equipped with our LVF Monochromators, filters, and spectrometer. The instrument is upgradable and can be equipped with non-isotopic detection technologies:UV/vis absorbance, Fluorescence intensity, including FRET,Luminescence (flash and glow), including BRET,Fluorescence polarization/anisotropy,Time-resolved fluorescence, including TR-FRET AlphaScreen / AlphaLISA / AlphaPlexTM. Atmospheric Control Unit, temperature incubation, multiple shaking, well scan and reagent injectors make the CLARIOstar Plus the ideal platform for any live cell-based assay.
Thermal Imaging camera. Pro-Series Infrared Camera with Ignite Cloud.
Core provides access to functional, up-to-date equipment for flow cytometric analysis and cell sorting, histological samples preparation, and single cell RNA sequencing which is essential for all researchers in immunology, infectious disease, and cell biology and is highly useful for scientists in other related fields.
Core offers flow cytometry, imaging, and histology resources.Provides expertise in the fields of imaging, histology, and flow cytometry, physical space and instruments, critical support through the whole process, from hands-on training to experiment design and data analysis.
Core enables collection of high-quality data for researchers employing variety of social and behavioral methods. This facility provides tools necessary for researchers to study interactions between human systems and other complex phenomena like public health and ecosystems.
Facility supports basic and applied research and education in all science, engineering, and STEM disciplines. Specializes in complementary surface, interfacial, and bulk characterization of materials via high-resolution imaging and spectroscopy. The lab promotes interdisciplinary collaboration between research, educational, and industrial fields.
Core provides single particle analysis and cryo-electron tomography. Instrumentation includes 200 kV Talos Arctica with Gatan K3 camera, 120 kV Tecnai Spirit, and Vitrobot Mark IV allowing imaging of biological structures at single nanometer to sub-nanometer resolutions, and thus enable 3D modeling of cells, viruses, proteins, nucleic acid, and other soft matter at the atomic level.
Promega glomax software for older but still functional luminometer models. GloMax 96 Software requires that Microsoft Excel is also installed on the PC. GloMax 96 Software is compatible with Excel 2003, 2010 and 2013 versions.
Portal provides information about nationwide study of more than 50,000 individuals to determine factors that predict disease severity and long-term health impacts of COVID-19.
Software tool as Nanopore basecalling using Squeezeformer network to improve basecalling accuracy over recurrent neural network (RNN)-based model and Transformer-based models.
Portal provides access to cancer genomic data from variety of analyses: clinical, copy number, miR, miRseq, mRNA, mRNAseq, mutation and pathway analyses. Provides comprehensive suite of interdependent analyses of those data, including: correlations, clustering, and GISTIC and MutSigCV. Companion portal to the Broad Institute GDAC Firehose analysis pipeline, and was developed to cull and analyze data generated by The Cancer Genome Atlas (TCGA), which characterizes and identifies genomic patterns in human cancer models.
Web tool for comparison of gene expression in normal, tumor and metastatic tissues.
Software application encompassing autonomous feature extraction and feature representation enhancement for PPIs and protein complexes inference. FREEPII establishes feature maps that are consistent with model training, and emphasizes learning the feature representation of proteins rather than the feature representation of PPI, reducing the computational complexity from N^2 to N (N: number of proteins). FREEPII uses protein sequences to expand the information available for calculating data similarity between proteins. Furthermore, it introduces network-level information into the final feature representation to rescale the strength of interactions present in CF-MS data.
Institutionally available research service unit managed on behalf of the Medical College by the Department of Cell Biology, Neurobiology and Anatomy. OCAM-EM encompasses both Light and Electron Microscopy services.
Core to advance understanding of mechanism of vascular dysfunction in chronic disease, identify how vascular dysfunction contributes to exercise intolerance, evaluate how exercise training improves vascular dysfunction and exercise intolerance using innovative clinical trial designs.
Intuitive single-button gas chromatography system, that provides ease of use with minimal instrument interaction and full data system control. Offers user-exchangeable, instant connect injector and detector modules and fast oven performance with exceptional retention time stability. Used for detecting wide range of compounds and it is sensitive and user friendly.