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Website serves as digital resource for plastic surgery professionals. Educational and resource platform dedicated to plastic surgeons, trainees, and researchers. Provides access to curated content, including links to major plastic surgery societies, journal repositories, clinical resources, and upcoming events. Serves as comprehensive hub for continuous professional development and collaboration in the field of plastic surgery.
Software tool that combines the utility of NanoFilt and NanoLyse, for filtering sequencing reads based on quality, length, and contaminating sequences, delivers 7-fold speed up compared to the Python implementation, making use of the Rust-Bio library and Rust bindings to minimap2.
Cellular Imaging Core facility is light microscopy core in Boston Children's Hospital's Neurobiology Program. The Core maintains systems for Widefield, confocal, multiphoton, and lightsheet light microscopy as well as sample preparation and image processes tools and technologies to assist the microscopy community of Boston Children's Hospital in addition to the surrounding greater Boston area. Core services and equipment are available to all upon request, contact core staff for access.
Core provides in vitro HIV-1 neutralizing antibody assay services. Serves as resource for assessing breadth and potency of HIV-1 neutralizing antibodies, and for characterizing neutralization phenotype of HIV-1 isolates. Investigators send monoclonal antibodies or serum samples from vaccinated or HIV-1-infected individuals to the core for in vitro testing using the validated TZM.bl neutralizing antibody assay. The core also has the capability to phenotype primary HIV-1 isolates for sensitivity to broadly neutralizing antibodies. GCLP-compliant, In vitro testing of monoclonal antibodies or seurm samples, Validated TZM.bl neutralizing antibody assay, Phenotoyping of primary HIV-1 isolates.
Core offers services from sample processing from both fresh and frozen, as well as fixed cells or tissues to library preparation and next-generation sequencing (NGS) for bulk DNA/RNA sequencing and single-cell/nuclei sequencing. For single-cell studies, core is equipped with Chromium X system from 10X Genomics. Sequencing capabilities include Illumina Novaseq6000 and NextSeq 500. Offers single cell spatial transcriptomics with CosMx SMI platform. Other equipped includes CytAssit instrument from 10X genomics for VISIUM spatial transcriptomic and QIAConnect from Qiagen for nucleic acid and protein extraction.
Software tool for partial reimplementation of bcftools for VCF Zarr.
Software tool to convert bioinformatics file formats to Zarr.
Software tool for ultrafast taxonomic profiling and genome querying for metagenomic samples by abundance-corrected minhash. Species-level metagenome profiler that estimates genome-to-metagenome containment average nucleotide identity (ANI) through zero-inflated Poisson k-mer statistics, enabling ANI-based taxa detection. Offers precise, efficient profiling with accurate containment ANI estimation even for low-coverage genomes.
Algorithm for registration of stained fresh frozen serial images. Used for registration of stained histology images.
Software Python framework for integratig spatially resolved multi-omcis data. Framework capable of coordinating different spatial resolutions and sampling organizations between different spatial modalities to create one spatial omics dataset.
Core offers services including assay development, FDA-drug library screening, unbiased compound screening, high-content imaging and screening. Facility can empower researchers to repurpose existing FDA-approved drugs and discover new compounds for drug development. Provides affordable platform for discovering therapeutic targets and interventions, supporting drug development from target identification to screening and validation. Features HTS facilities, including Biomek i7 Liquid Handling system, Pherastar FSX plate reader, ImageXpress Micro Confocal, and Pala cell sorter.
Privately held German medical technology company headquartered in Munich, Bavaria. Brainlab develops software and hardware for radiotherapy and radiosurgery, and the surgical fields of neurosurgery, ENT and craniomaxillofacial, spine surgery, and traumatic interventions. Brainlab software and hardware devices create and enhance data to improve critical surgeries, radiosurgery treatments and operating room efficiency.
Software tool used to assess heart rate variability.
Software tool for analysis of biological rhythms, particularly circadian rhythms, using curve fitting methods to model time-series data and determine key parameters such as period, amplitude, and phase.
Software R package that provides scientific-themed color palettes for ggplot2, offering visually appealing and publication-quality color schemes inspired by scientific journals and data visualization standards.
Software R package that enhances text rendering in ggplot2 by allowing the use of Markdown, HTML, and rich text formatting for annotations, labels, and titles in plots.
Provides services and instrumentation including Illumina Next-Generation Sequencing, Single Cell Analysis and Spatial Transcriptomics. These techniques are developed and optimized by our lab scientists to deliver the highest-possible quality sequencing data from a wide variety of sample types such as peripheral blood, bone marrow, fresh frozen tissue and FFPE-derived tumor samples.
High-throughput experiment- and reference-guided database of traditional Chinese medicine.
Software segmentation toolkit to segment the Nanopore RNA signal. Preprocessing ONT-Nanopore RNA sequencing reads.
Software tool for quality control of short- and long-read sequencing data. Fast sequencing data quality metrics. Features adapter search, overrepresented sequence analysis, and duplication analysis and supports FASTQ and uBAM inputs.