Curator Dashboard

Core provides advanced mass-spectrometric instrumentation and for both proteomics and metabolomic experiments. Performs qualitative and quantitative analysis of proteins and post-translationally modified peptides and both targeted and untargeted LC/GC-MS based metabolomics.

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• 1 year ago - submitted by Matthew Rudy

Software R package for scRNA-seq normalization. Uses Simple Good-Turing estimator for the per cell relative gene expression estimation.

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• 1 year ago - submitted by Martin Fahrenberger

Software tool for formatting PhenoImager TIFF/OME-TIFF metadata for compatibility with MCMICRO workflow.

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• 1 year ago - submitted by Kresimir Bestak

Software tool for automated projection pursuit clustering. Alternative clustering approach that alleviates the curse of dimensionality by sequentially projecting high-dimensional data into a low-dimensional representation.

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• 1 year ago - submitted by Evgeniy Tabatsky

Core is equipped with instrumentation in mass spectrometry, sample preparation, and automation technology. Bruker timsTOF Ultra 2 ultra-high speed and sensitivity mass spectrometer for single cell and other low input proteomics methods. It comes equipped with the Bruker nanoElute 2 UHPLC and the alternative EvosepOne HPLC for high throughput applications. Sample preparation can be automated using the Opentrons Flex liquid handling robot.

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• 1 year ago - submitted by Edyta Vieth

Core provides researchers with access to high-quality human induced-pluripotent stem cell (iPSC) production, expansion, validation, and quality control services, while strictly adhering to approved protocols, ensuring high-quality standards and consistency throughout the process.

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• 1 year ago - submitted by Edyta Vieth

Core produces and distributes of MHC/peptide tetramers and related reagents. Production and distribution to the research community of major histocompatibility complex (MHC) tetramers and related reagents for detection of T cell responses to viruses, bacteria, parasites, tumors, auto-antigens, and other model antigens. Reagents are provided to qualified investigators at no cost, except for shipping and handling fees and in cases where investigator is asked to provide the TCF with peptide or other appropriate ligands.

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• 1 year ago - by Anonymous

Software tool for RNAi-target design and off-target prediction. Used for long double-stranded RNAi-target design and off-target prediction.

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• 1 year ago - by Anonymous

Software tools to find circRNAs in RNA-seq data. Used to detect head-to-tail spliced (back-spliced) sequencing reads, indicative of circular RNA (circRNA) in RNA-seq data.

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• 1 year ago - by Anonymous

Software tool for utilizing sequence intrinsic composition to classify protein-coding and long non-coding transcripts.

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• 1 year ago - by Anonymous

Software suite to search and cluster huge protein and nucleotide sequence sets. Sensitive protein sequence searching for analysis of massive data sets. Used for ultra fast and sensitive search and clustering.

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• 1 year ago - by Anonymous

Web application to automate germline genomic variant curation from clinical sequencing based on ACMG guidelines. Aggregates multiple tracks of genomic, protein and disease specific information from public sources.

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• 1 year ago - submitted by Michael Conry

Time-of-Flight mass spectrometer for high-speed acquisition of highly multi-parametric single cell data. Simultaneously resolves multiple parameters with minimal signal overlap, providing insights into the functional and phenotypic complexity of biological systems at the single-cell level. Analyzes cells labeled with panel of reagents conjugated to stable metal isotopes using time-of-flight mass cytometry technology. Includes over 120 detection channels and 35 Maxpar metal probes.

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• 1 year ago - by Anonymous

CyTOF instrument uses atomic mass spectrometry to allow simple, independent detection of up to 33 metal labeled antibodies (and two DNA intercalators) based on currently available reagents. Has capacity to measure 100 independent signals. CyTOF system is inorganic mass spectrometer specifically built for biologists and single cell applications. Inductively coupled plasma mass spectrometer used extensively by analytical chemists and is proven in the quantification of elements and stable isotopes in variety of complex matrices.

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• 1 year ago - by Anonymous

Web interface to easily import, visualize, and analyze brain signals. Used for analysis of longitudinal neural recording data.

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• 1 year ago - by Anonymous

Core provides broad range of spatial transcriptomic and targeted proteomics services including: Conventional nCounter analysis to determine RNA abundance, GeoMx Digital Spatial Profiling platform to determine protein and RNA abundance, CosMx Spatial Molecular Imaging platform for single cell spatial analysis of RNA and protein.

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• 1 year ago - submitted by Amy von Eberstein

Software tool as data-driven network modeling algorithm for drug response analysis in cancer.

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• 1 year ago - submitted by Augustin Luna

Data Science Platform focuses on Artificial Intelligence, Signal Processing, Computer Vision with the aim of advancing the research of Rockefeller Laboratories. DSP owns and operates fully dedicated computing infrastructure, equipped with state of the art GPUs and large storage capabilities.

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• 1 year ago - submitted by Claire Warner

Mass spectrometer used for research, particularly in proteomics and metabolomics, leveraging Trapped Ion Mobility Spectrometry (TIMS) and Parallel Accumulation Serial Fragmentation (PASEF) technologies for enhanced 4D-omics capabilities.

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• 1 year ago - by Anonymous

Mass spectrometry (MS)-based proteomics instrument designed for shotgun proteomics and phosphoproteomics, leveraging Parallel Accumulation Serial Fragmentation (PASEF) technology to enhance speed, sensitivity, and resolution.

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• 1 year ago - by Anonymous