Curator Dashboard

Core provides services, from DNA and RNA extraction from diverse sample types such as tissue, stool, and bacterial isolates to next-generation sequencing, including whole-genome sequencing, total RNA-seq, metatranscriptomics, and dual RNA-seq, along with expert bioinformatics support. Core expertise spans 16S rRNA amplicon sequencing, shotgun metagenomics, metatranscriptomics, meta-omics analysis of dual RNA-seq, and single-cell RNA-seq data. Core also assists with experimental design and power calculations to ensure statistically robust results, offering consultation at every stage, from experimental design to data interpretation and troubleshooting.

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• 1 year ago - submitted by Matthew Rudy

Sciex 7500+ Triple Quadrupole Liquid Chromatography/Mass Spectrometry System enables rapid, sensitive screening for large panels of analytes, including metabolites, lipids, and environmental contaminants. SCIEX 7500+ system minimizes downstream contamination of the ion optics, maintaining instrument robustness over greater periods than the benchmark triple quadrupole mass spectrometers.

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• 1 year ago - submitted by Edyta Vieth

Web application as crowd-sourcing platform to improve consensus and use of drug-target interactions. Users can search, view and download bioactivity data using various compound, target and publications identifiers.

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• 1 year ago - by Anonymous

Facility offers preparation of samples from fresh or fixed tissue through to scanned images. Provides training to prepare and use equipment to embed, section and hand stain tissues as required. Offers three different types of wax for embedding and sectioning as required. Fully equipped for methyl methacrylate and glycol methacrylate embedding and sectioning (including larger samples), freeze microtomy and high throughput slide imaging using our Zeiss Axioscan Z1.

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• 1 year ago - by Anonymous

Provides access to imaging systems. Offers researchers technologies for multi-modality, non-invasive approaches to imaging on small, live animals, or tissues and organs extracted from animals . Our equipment can be used for pre-clinical models and non-biological samples.

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• 1 year ago - by Anonymous

Core is a multi-user facility located on the 4th floor in the Translational Research Building (TRB) at A4-132. Histology facility offers services for processing tissue samples, automated equipment for tissue processing, paraffin embedding, micro-sectioning, and staining. Our technicians offer consultation, experimental design, and troubleshooting and work closely with researchers to get the most optimal tissue sections tailored to each project. The facility also provides training on the microtome and paraffin embedder to allow flexibility in workflow.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Analytical Core for Metabolomics and Nutrition (ACMaN) is located on the first floor of the Varity Building. ACMaN allows researchers to analyze and track biological compounds, such as nutrients to track how these small molecules change during course of disease or treatment to better understand the disease itself and to develop new diagnostic tools and therapies. ACMaN plays role in research on metabolic diseases, hormones, and the effects of nutrition on childhood development.

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• 1 year ago - submitted by Edyta Vieth

Facility is equipped with range of advanced microscopes, from traditional light microscopes to cutting-edge super-resolution and live cell imaging systems.Provides imaging and analysis services.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Facility provides equipment for flow cytometric analysis and full-service cell sorting, as well as flow cytometry training and education for new users.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Provides small animal imaging services. Facility provides multi-modality imaging, advanced data analysis, image fusion resources, custom chemistry, and satellite animal facility for longitudinal studies.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Core provides expertise in the design and implementation of preclinical trials to test new drugs, drug combinations and novel therapeutic modalities in mouse models of human diseases.

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• SciCrunch
• 1 year ago - submitted by Edyta Vieth

Software reference-free intraspecies sample anomalies detetion tool based on k-mer counting.

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• 1 year ago - submitted by zhantian xu

Software interface for interacting with brain atlases. Python client to brain atlas framework that integrates brain parcellations and reference spaces at different spatial scales, and connects them with broad range of multimodal regional data features. It aims to facilitate programmatic and reproducible incorporation of brain parcellations and brain region features from different sources into neuroscience workflows.

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• 1 year ago - by Anonymous

Integrated Cell Browser features integrated single-cell RNA sequencing (scRNA-seq) and single cell ATAC-seq data from human donor-specific pancreatic islet cells. The browser enables detailed interrogation of single cell RNA-seq and single cell ATAC-seq data through intuitive visualizations. Within the single-cell browser, users can first identify and filter single-cell datasets and dataset collections. Users can visualize interactive plots of cell type clusters, gene expression, cell type abundance, and marker gene expression. Donors and their data were provided by external programs described here.

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• dkNET
• 1 year ago - submitted by Ko-Wei Lin

Knowledge Graph developed for the study of the human pancreas. By leveraging large language models (LLMs) and diverse data types, PanKgraph enables users to uncover biological connections and insights into diabetes pathogenesis. Previously disjointed entities such as genes, single nucleotide polymorphisms (SNPs), and pancreatic expression quantitative trait loci (eQTLs) can now be explored and connected in innovative ways.

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• 1 year ago - submitted by Ko-Wei Lin

Centralized knowledge base of the human pancreas for diabetes research. Integrates diverse type 1 diabetes (T1D) datasets with expert-curated knowledge in centralized, open-source data hub. Since users will ultimately be able to contribute their own data, this will be repository for reproducible, collaborative research within the pancreas and T1D realms.

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• dkNET
• 1 year ago - submitted by Ko-Wei Lin

Resource that integrates biomedical terms and biomedical relationships. This collection is curated from PubMed abstracts and biomedical repositories, offering unparalleled wealth of knowledge for researchers and practitioners in the field. The database is coupled with RESTful APIs and user-friendly web interface.

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• dkNET
• 1 year ago - submitted by Ko-Wei Lin

Database that uses knowledge graph to consolidate genomic datasets and annotations. Graph database for researchers to explore and investigate human genome, epigenome, transcriptome, and 4D nucleome. Genomic entities and relationships are represented as diverse nodes and edges with properties.

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• dkNET
• 1 year ago - submitted by Ko-Wei Lin

Core provides services in Assay Development, Assays Experimental Design, Immune Monitoring, Cytokine Assays, ELISA, multiplex Flow based and Luminex based Bead Arrays, Project Based Flow Cytometry and Data Analysis.

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• 1 year ago - submitted by Rafal Pacholczyk

Software tool as framework for knowledge graph construction and the current 4 KGs. Used to extract and integrate diverse knowledge about microbes from variety of structured and unstructured sources.

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• 1 year ago - submitted by Brook Santangelo