Curator Dashboard

Core provides glassware washing and sterilization of all types of glassware and pipettes. Facility maintains stock glassware in common storage area. Glassware personnel collect glassware from laboratories daily and cabinets are replenished regularly. Autoclaving of materials is offered on daily basis. Core can accommodate any special requests. Glassware Core maintains stock of all types of sterile laboratory glassware and pipettes in common storage area.

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• 1 year ago - submitted by Matthew Rudy

Core provides specialized cell culture services , ensures high-quality and contamination-free cultures by employing aseptic techniques and maintaining Mycoplasma and Quarantine facilities. Offers cell banking, with capacity to freeze and store up to 10,000 vials. Facility provides walk-in warm room and cold room, spinner apparatus capable of handling over 20 liters of cells in suspension, and roller bottle machine that accommodates more than 200 roller bottles. Additional equipment includes automated cell counter and ELISA reader.

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• 1 year ago - submitted by Matthew Rudy

Software tool as simple test framework for Nextflow pipelines. Enables pipeline developers to test individual process blocks, workflow patterns and entire pipelines in insolation.

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• 1 year ago - by Anonymous

Software Python package for modular causal inference analysis and model evaluations. Used for inferring causal effects from observational data.

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• 1 year ago - by Anonymous

Stand-alone Raspberry Pi-enabled IoT system to monitor near-realtime sensor data in MyVivarium web app. Used to track environmental conditions of vivaria.

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• 1 year ago - submitted by Jensen Palmer

Cloud-based lab animal colony management application with realtime ambient sensing. Platform for managing vivaria. It features cage management, user management, lab management, and real-time environmental monitoring with IoT sensors.

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• 1 year ago - submitted by Jensen Palmer

Web application as resource of known and predicted human ubiquitin ligase substrate interaction network. E3-substrate interactions are derived from six data sources: mannual cruration, protein ortholog, protein domain, protein motif and network topology.Designed to explore predicted and reported E3-substrate interactions for query E3 or substrate, and ubiquitination sites for substrate protein.

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• 1 year ago - by Anonymous

Core provides services for genomics analysis, from sample processing through data generation. Available technologies focus on Illumina RNA and DNA sequencing. RNA-seq can be performed from a variety of sample types, including purified total RNA, cell populations (including low input samples of 50-1000 cells), or single cells (either plate-sorted rare populations or high-throughput 10x single-cell analyses). DNA-seq pipelines can also be performed, including bulk CUT and Tag/CUT and RUN, and ATAC-seq and single cell ATACseq and multiome capture. Custom prepared libraries can also be submitted for sequencing. Core laboratory houses Illumina sequencers, NextSeq2000 instruments and Miseq, plus 10x Chromium X and 10x CytAssist. Additional equipment includes ThermoFisher Kingfisher Flex, for extracting nucleic acid from variety of sample types using magnetic bead technology with throughput of up to 96 samples. Qiagen QIAcube Connect instruments automate extraction of nucleic acid using spin column technology. Ancillary equipment for sample processing includes Formulatrix Mantis Liquid Handler, Agilent TapeStation 4200 and Tecan NanoQuant.

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• 1 year ago - submitted by Edyta Vieth

Core provides flow cytometry services. Staff members will help with experimental design, instrument training, sample acquisition, data analysis with software provided, and conventional/spectral cell sorting.

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• 1 year ago - submitted by Edyta Vieth

Compact stereotaxic instrument designed for use with knock-out and transgenic mice. Instrument includes 100 micron, 3-axes left-hand manipulator arm, mouse snout clamp and tooth bar, dual-sided ear bars, and corner clamp probe holder. Stoelting’s Motorized Stereotaxic Manipulator Arms are designed for fast, accurate positioning during stereotaxic surgery. Motorized manipulator arms employ touchscreen display for easy-to-control movement of each axis. Manual movement is available anytime. Optional Drill feature available.

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• 1 year ago - by Anonymous

3D-Hub-O specializes in production, manipulation and analysis of organoids from normal and tumor tissues. Physiological platform for research on living pathological tissues. Platform participates in knowledge transfer through customized training of specific organoid culture carried out by platform staff.

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• 1 year ago - by Anonymous

System for non-invasive, real-time, and label-free evaluation of cellular function in vitro, particularly for monitoring electrical activity of excitable cells like neurons and cardiomyocytes, as well as tracking cell growth and death. Used in neuroscience to measure electrical activity of network of cultured neurons.

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• 1 year ago - by Anonymous

Swedish national resource supporting precision medicine research in Sweden through access to data sources, customised dashboards and guidance on data management with focus on making data FAIR and reusable.

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• 1 year ago - submitted by Natashia Benzian Olsson

Core dedicated to supporting single cell and spatial biology experiments on the Evanston campus. Home of flow cytometry. Offers single cell encapsulation and library preparation services using the 10X Genomics platform. Provides experiments consultations.Shared use, training, and service facility. Instrumentation includes FACSDiscover S8 flow sorter, LSRFortessa flow analyzer, MERSCOPE spatial transcriptomics platform, 10X Genomics Chromium iX, Epredia NX70 Cryostat, QuantStudio 3 real-time PCR, VeritiPro Thermocycler, Agilent Bioanalyzer, Axiovert inverted microscope (DIC, Brightfield, 4 fluorescent channels), Revvity Cellometer K2 automated cell counter, Qubit 4 fluorometer, Nanodrop spectrophotometer. Services include assisted flow cytometry, 10X Genomics library preparation, spatial transcriptomics via MERSCOPE, cell counting, bioanalyzer analysis, bulk library preparation, and low input library preparation.

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• 1 year ago - by Anonymous

Software code for age prediction in fetal brain and organoid single cell data. This repository contains cell type agnostic models to predict the developmental age of brain cell types from single cell RNAseq data. Code contains 4 jupyter notebooks, which apply pretrained models to predict neurodevelopmental age of cell types in new human fetal brain and organoid datasets.

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• 1 year ago - submitted by Edyta Vieth

Interactive web application for drug screening data analysis. It includes comprehensive quality control statistics, dose-response curve fitting, and calculation of quantitative scoring parameters such as EC50, IC50, drug sensitivity score and AUC. Used to facilitate quality control, dose-response curve fitting, and data visualization.

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• 1 year ago - by Anonymous

U.S. Department of Agriculture Agricultural Research Service initiative hosted at Cornell University in Ithaca, New York. Assists USDA-ARS breeders by creating new opportunities in assimilating data-driven tools, technologies, and methods to remove barriers and more easily allow for the use of genomic insights. We integrate phenomics (trait analysis), genomics (genotypic data), data management, and software tools to help breeders increase the rate of genetic gain and create more healthy and nutritious specialty crops and animals. These gains improve on-farm production for many of America’s favorite specialty crops and animals.

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• 1 year ago - submitted by Moira Sheehan

Softwre framework for multi-scale footprinting analysis of single-cell ATAC-seq data. Designed to identify and visualize regulatory elements that drive cell-type-specific gene expression programs through footprinting. Uses deep learning model to predict activity of transcription factors from single-cell ATAC-seq data. Provides suite of visualization tools to explore calculated multi-scale footprints.

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• 1 year ago - by Anonymous

Software tools for manipulating scATAC-seq fragment files.

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• 1 year ago - by Anonymous

Platform to help scientists organize all biological knowledge into singular, unified resource that is searchable, accessible and capable of answering the most difficult questions in science. Used for bioinformatics analysis.

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• 1 year ago - by Anonymous