Curator Dashboard

Liganx is a free, browser-based molecular docking tool for small-molecule drug discovery. It docks compounds into wild-type and mutant protein structures side by side and reports the wild-type-minus-mutant difference in binding score (delta-delta), which is useful for studying drug resistance and selectivity. Ligand-efficiency and drug-likeness metrics are shown alongside the docking score. Runs entirely in the browser with no installation.

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• 21 hours ago - submitted by Arash Tadi

Software macOS application for TaqMan endpoint SNP genotyping. Calls genotypes from two-channel allelic discrimination data with five independent algorithms (ALCHEMY, BCGA, fitPoly, polar thresholds, robust Student-t mixture) and a configurable consensus; includes spectral compensation, QC metrics, Hardy-Weinberg and case/control association statistics, multi-plate cohorts, and publication-ready exports with R and Python reproducibility scripts. Reads RDML and tab-delimited endpoint exports; runs fully offline

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• 2 days ago - submitted by Mehmet Oktar Guloglu

Service shared resource that generates mouse models of human disease from project conception to strain delivery. We have expertise in pre-implantation mouse embryos, microinjection, mouse surgery, development of targeting and transgenic strategies, establishment of genotyping protocols, and cryopreservation and recovery of mouse germplasm.

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• 2 days ago - by Anonymous

Plasmid design and molecular cloning software developed by Fearless League (Leiden, Netherlands), available as a desktop application and in the browser. It supports plasmid map creation and annotation, in silico cloning simulation (restriction-ligation, Gibson/HiFi assembly, Golden Gate and Gateway), primer design, virtual digests and gel simulation, and Sanger sequencing trace alignment. An integrated, open-access genome browser lets users locate genes, design CRISPR guides in genomic context, and save regions with CRISPR and SNP tracks. Team workspaces provide shared plasmid libraries with role-based permissions. Imports SnapGene, GenBank and FASTA files.

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• 2 days ago - by Anonymous

Web application for human genetic variant literature discovery and evidence review. Used for clinical genetics literature search. It accepts variant identifiers and connects literature results with available source passages, variant aliases and provenance. Users can inspect variant mentions and export evidence and references to Excel. The service is in beta, with an account required for the workspace. Coverage depends on available sources, and outputs require professional review.

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• SciCrunch
• 2 days ago - by Anonymous

Web-based tool for researchers preparing manuscripts for journal submission. It provides automated manuscript feedback and citation checks to help authors identify issues and prioritize revisions. Authors remain responsible for verifying the feedback and meeting journal requirements.

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• SciCrunch
• 2 days ago - by Anonymous

Collects and stores the data, tissue, fluids and DNA of patients. Leverages clinical phenotyping by our physicians, our internally developed research database, a pathology image database and our biorepository, we can offer our investigators and partners highly characterized information and corresponding samples of respiratory and immunologic disease.

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• 3 days ago - submitted by Edyta Vieth

Provides specialized laboratory and sample-processing services to support human clinical and translational research studies.

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• 3 days ago - submitted by Edyta Vieth

Core provides sample preparation services to the Janelia Research Campus, including microdissection, cell isolation, FACS, nucleic acid extraction, etc for downstream short and long-read sequencing, as well as single-cell, single-nuclei, and spatial-omics applications.Instruments include Illumina NextSeq 2000, PacBio Vega, and 10X Chromium X.

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• 3 days ago - submitted by Edyta Vieth

Software phylogenetic tool designed for single-cell DNA sequencing (scDNAseq) data. Used to infer the joint history and evolutionary trees of single nucleotide variants (SNVs) and copy number alterations (CNAs) within tumors. Designed to be used with MissionBio's Tapestri data, where a small number of amplicons (50-300) are sequenced for thousands of single-cells.

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• 3 days ago - submitted by Friederike Christen

Desktop software for scientific curve and peak fitting on Windows, Linux and macOS (GPL-3.0-or-later). It supports composite models built from analytical formulas and built-in peak/background functions, parameter bounds and links, independent, sequential and global fitting, residual inspection and uncertainty analyses. Applications include Raman/IR spectroscopy, diffraction, kinetics and general x-y data. A Python API, command-line interface, YAML workflows and Python plugins support reproducible analyses.

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• 3 days ago - by Anonymous

Software R package to perform dose-response analysis and create dose response curve plots.

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• 3 days ago - by Anonymous

Web application for reading released, versioned scientific studies. It presents study results together with methods, source references, sensitivity analyses and limitations, so readers can inspect the basis and scope of a published scientific claim. It displays completed upstream study outputs; it is not a public data-submission portal or a browser interface for running new scientific computations. It does not provide patient-specific interpretation, diagnosis or treatment recommendations.

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• 3 days ago - submitted by Vladimir Mitev

Web application designed to accelerate drug target discovery by turning raw Genome-Wide Association Studies (GWAS) data into ranked loci, fine-mapping, candidate genes, and tissues and biological mechanism hypotheses, with source evidence, methods and uncertainty kept visible.

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• 3 days ago - submitted by Vladimir Mitev

Software tool to assess the quality of sequence read data. Falco was conceived as an emulation of the popular FastQC software to check large sequencing reads for common problems.

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• 3 days ago - submitted by Joachim Wolff

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• 3 days ago - submitted by Milena Vitale

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• 3 days ago - submitted by Milena Vitale

Core provides School of Medicine faculty and researchers with nuclear magnetic resonance (NMR) tools and expertise for the detailed analysis of biological macromolecules in health and disease. Offers services in High Field NMR Facility for Solution and Solid State NMR Studies of Biomolecules. Equipped with solution-based NMR spectrometers (all with high-sensitivity cryogenically cooled probes) and solid-state NMR spectrometers.

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• 4 days ago - by Anonymous

Software Python package for analysis of large-scale microscopy datasets. Provides tooling for image preprocessing, cell/particle segmentation, morphology analysis, fluorescence quantification, and batch processing pipelines. Supports ND2 files from Nikon microscopes LIF files from Leica microscopes. The package integrates with popular scientific Python libraries for streamlined high-content screening and quantitative microscopy workflows.

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• 4 days ago - by Anonymous

Software R package as multi-tissue transcriptional age calculator. RNAseq-based transcriptomic aging algorithm.

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• 4 days ago - by Anonymous