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Showing 20 out of 29,160 Resources on page 1

Nikon: AXr-Multiphoton Intravital Microscope System

System provided by Augusta University. Highly configured Nikon AXr-Multiphoton and single-photon confocal microscope system maintained as a major capital equipment investment for fluorescence-based live animal (intravital) imaging and cleared tissue imaging. The system features a fast-speed resonant scanner (4k imaging), a high-resolution galvo scanner (8k imaging), and a specialized piezo stage system for rapid Z-axis volumetric imaging. To maintain strict physiological stability for in vivo subjects without inducing thermal laser shift, the objective and specialized animal stage area are isolated within a custom-engineered $40,000 heated blackout enclosure. It is uniquely configured with specialized large working distance objectives, including a CFI75 Apochromat 1.0 NA 20x Water Immersion objective (2.8mm WD) and a CFI90 1.0 NA 20XC Glycerol Immersion objective (8.2mm WD) to support deep tissue penetration. The instrument operates as a discrete standalone resource dedicated to intravital research; it is physically separated from the main imaging core in a different building and is housed directly within the animal facility.

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  • 57 minutes ago - by Anonymous

Scalebar App

Web app that adds correct scale bars to microscopy images (SEM, TEM, light, fluorescence, diffraction). It reads the scale from the file metadata (TIFF, DM3/DM4) or from the instrument’s info bar, and exports figures with a calibrated scale bar and a methods sentence for papers.

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  • 6 hours ago - submitted by Scalebar App

Studyflow

Open source visual notation and tools, built on BPMN 2.0, for describing an experimental study as one executable diagram that serves as its protocol, implementation, data model, analysis plan, provenance record, and publication figure.

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  • 8 hours ago - submitted by Morteza Ansarinia

VSQRD

VSQRD is an AI system for whole-slide image analysis in pathology and histology. The user writes the analysis once as a method in plain language, and VSQRD analyses every slide in a study without further input. For each slide it returns quantitative results, masks that can be viewed over the slide, the assumptions it made, and a full record of its reasoning. It supports H&amp;E and special stains, immunohistochemistry, multiplex fluorescence, and flow and mass cytometry. No annotation or model training is needed.

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  • 13 hours ago - submitted by Vivien Henz

Medical College of Wisconsin Precision Irradiation Core Facility

Core utilizes x-ray instruments capable of irradiating both small animals and cells. Current units in operation include the SmART+, X-RAD 320, and CellRad. The core can perform whole-body irradiations as well as targeted irradiation of small volumes, tumors, and cells at various dose rates. Core technicians will operate the units on the requestor’s behalf. The core also breeds and houses the only WAG/Rij strain rats in the United States which are available for purchase. The core also offers specific animal handling services for an hourly fee which includes jugular bleeding in rats. Consultation for irradiation projects and dosimetry is also available.

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  • 18 hours ago - submitted by Tracy Gasperetti

iNEXT

Software R package for rarefaction and extrapolation of species diversity (Hill numbers). Used for interpolation and extrapolation.

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  • RRID
  • 19 hours ago - by Anonymous

FastSP

Software Java tool for computing alignment error (SP-FN) quickly and using little memory. Used for comparing two very large alignments efficiently. Used for linear time calculation of alignment accuracy.

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  • 20 hours ago - by Anonymous

Alistat

Software application to support the Minimum Reporting Standard. Used for quantifying the completeness of multiple sequence alignments used in Phylogenetic and Phylogenomic research.

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  • 20 hours ago - by Anonymous

CIAlign

Software highly customisable command line tool to clean, interpret and visualise multiple sequence alignments.

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  • 20 hours ago - by Anonymous

TWILIGHT

Multiple sequence alignment software tool optimized for speed, accuracy, scalability, and memory constraints, with both CPU and GPU support, to build ultralarge alignments at high speed even on memory-constrained devices. Used to align over 8 million publicly available SARS-CoV-2 sequences, setting a new standard for large-scale genomic alignment and data analysis.

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  • 20 hours ago - by Anonymous

WITCH

Software tool for multiple sequence alignment with WeIghTed Consensus Hmm alignment. Used to align unaligned sequences and find consensuses.

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  • 20 hours ago - by Anonymous

CONCOMPRA

Software tool that allows the detection of closely related strains within a community by drafting and mapping to consensus sequences.

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  • 20 hours ago - by Anonymous

SpheroSeg

Web platform for bright-field spheroid segmentation that combines a large annotated dataset, standardized model benchmarking, and an accessible web-based analysis workflow. Used for deep-learning segmentation and morphometric analysis of tumour spheroids in microscopy images. Users upload images, correct the predicted outlines in an editor, and export masks, polygons and per-image metrics (area, perimeter, circularity and others) without installing anything. A module for disintegrating spheroids segments the dense core and the corona of dispersing cells and returns the outside-core fraction.

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  • 21 hours ago - by Anonymous

nucleoSim

Software R package to generate a synthetic map with reads covering the nucleosome regions, as well as a synthetic map with forward and reverse reads emulating next-generation sequencing. Can generate synthetic hybridization data for “Tiling Arrays.” The user can choose from three read-positioning distributions: Normal, Student, and Uniform. Visualization tool to explore the synthetic nucleosome maps. Used to simulate synthetic nucleosome maps.

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  • 21 hours ago - submitted by Astrid Deschenes

Miltenyi Biotec: MACSQuant Tyto Lux Cell Sorter

Multiparameter microfluidic cell sorter designed to isolate living cells gently and safely. Four lasers cartridge-based cell sorter uses a patented low-pressure microchip valve to preserve the viability and functionality of fragile or rare cell populations (such as stem cells, neurons, or delicate primary cells).

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  • 21 hours ago - submitted by Camille Stegen

Diasorin: Luminex xMAP INTELLIFLEX System

Compact, flow-based, bead-based multiplexing platform used for life science and pharmaceutical research to simultaneously measure up to 500 different protein or nucleic acid targets (analytes) in a single small sample well (such as a 96-well or 384-well plate). Uses color-coded microscopic beads (microspheres), where each distinct bead set is coated with a specific capture molecule (like an antibody or oligonucleotide). Incorporates a violet laser alongside the standard lasers, allowing researchers to measure two different parameters per analyte simultaneously (ideal for applications like antibody isotyping or free-versus-bound drug assays).

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  • 22 hours ago - by Anonymous

Agilent: NovoCyte Opteon Spectral Flow Cytometer

Spectral flow cytometer is a high-dimensional cell analysis instrument used to measure the physical and chemical characteristics of individual cells and sub-micron particles at a high throughput. Instead of traditional compensation, it collects full emission spectra and uses spectral unmixing to separate overlapping fluorochromes and subtract intrinsic cellular autofluorescence (from molecules like NADH or flavins). This greatly improves the resolution of dim signals and rare cell subsets. Optimized with dual 488 nm and 405 nm side-scatter (SSC) optics to detect and resolve tiny particles down to 80 nm—such as exosomes, platelets, and bacteria—alongside larger cells in the same sample. Features up to 5 lasers and 73 detectors, allowing researchers to simultaneously analyze 40 or more fluorescent markers on a single cell.

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  • 22 hours ago - by Anonymous

Utilvo DICOM Viewer Online

Web-based tool that lets you open and inspect medical imaging files (such as CT scans, MRIs, and X-rays) directly inside your web browser without installing specialized software. 100% client-side, zero-upload DICOM Part 10 (PS3.10) clinical PACS sandbox and multi-frame diagnostic viewer for X-Ray Angiography (XA), CT, MRI, CR, and DX series. It performs local Little Endian binary parsing, 16-bit Hounsfield Window Width / Window Level (WW/WL) VOI LUT transformations, multi-frame cine loop playback (15+ FPS), geometric transforms (Invert, Rotate 90, Flip H/V, Zoom/Pan), spatial caliper/angle measurements, and pseudo-color lookup palettes (Grayscale, Hot Iron) strictly inside browser memory with zero server-side PHI/PII telemetry.

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  • SciCrunch
  • 1 day ago - submitted by Islam Ayoub

McGill University Flow Cytometry Core Facility

Core provides laser-based cell analysis, cell sorting, and technical training to the scientific community. Researchers use standard and full-spectrum flow cytometers (such as the BD FACSCanto II, BD LSR Fortessa, and Cytek Aurora) to analyze the physical and chemical characteristics of single cells or particles (such as cell size, granularity, and multi-parameter fluorescence). The core offers mandatory two-part training (theory and hands-on operation) so researchers can run analyzers independently, operator-assisted sorting services, experimental design consultation, and data analysis software (such as FlowJo).

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  • 3 days ago - submitted by Camille Stegen

Nicoya Lifesciences: Nicoya Alto Surface Plasmon Resonance system

Automated digital benchtop system, designed to measure real-time, label-free molecular interactions (such as antibody-antigen binding kinetics and affinity. Alto uses voltage-controlled electrodes to move discrete nanoliter-sized droplets across a single-use disposable cartridge. Requires as little as 2 µL of sample for a full kinetic profile.

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  • 3 days ago - by Anonymous