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Effects of remifentanil preconditioning on factors related to uterine contraction in WISH cells.

  • Cheul-Hong Kim‎ et al.
  • Journal of dental anesthesia and pain medicine‎
  • 2019‎

Preterm labor and miscarriage may occur in stressful situations, such as a surgical operation or infection during pregnancy. Pharyngeal and buccal abscess and facial bone fractures are inevitable dental surgeries in pregnant patients. Remifentanil is an opioid analgesic that is commonly used for general anesthesia and sedation. Nonetheless, no study has investigated the effects of remifentanil on amniotic epithelial cells. This study evaluated the effects of remifentanil on the factors related to uterine contraction and its mechanism of action on amniotic epithelial cells.


Anti-inflammatory effect of remifentanil in lipopolysaccharide-stimulated amniotic epithelial cells.

  • Cheul-Hong Kim‎ et al.
  • Journal of dental anesthesia and pain medicine‎
  • 2019‎

Sometimes general anesthesia is required for dental surgery in pregnant women. Facial bone fractures or neck abscess should be treated immediately. Dental surgery, however, creates a stressful situation that can cause inflammation. Inflammatory responses are a well-known major cause of preterm labor and preterm birth. Here we demonstrate the effects of remifentanil on the factors related to preterm labor and its mechanism of action on amniotic-derived epithelial cells (WISH cells).


Effectiveness of dexamethasone injection in the pterygomandibular space before and after lower third molar surgery.

  • Kalaya Sitthisongkhram‎ et al.
  • Journal of dental anesthesia and pain medicine‎
  • 2020‎

Previous studies have investigated the effects of dexamethasone injections into the pterygomandibular space and compared them to those of controls; however, the effects of dexamethasone injections before and after lower third molar surgery on postoperative complications have not been studied. This research investigated the postoperative sequelae of dexamethasone injections before and after surgery into the pterygomandibular space. The aim of this study was to evaluate the effects of preoperative and postoperative injections of 4 mg of dexamethasone into the pterygomandibular space on postoperative pain, facial swelling, and the restriction of mouth opening following lower third molar surgical removal.


Changes in blood flow at the mandibular angle and Horner syndrome in a rat model of superior cervical ganglion block.

  • Kazutoshi Kubota‎ et al.
  • Journal of dental anesthesia and pain medicine‎
  • 2018‎

A stellate ganglion block (SGB) causes increased blood flow in the maxillofacial region, exhibiting the potential for regenerative effects in damaged tissue. The focus of this study was to understand the efficacy of SGB for regenerative effects against nerve damage. A rat model of the superior cervical ganglion block (SCGB) was created instead of SGB, and facial blood flow, as well as sympathetic nervous system function, were measured.


Use of an animated emoji scale as a novel tool for anxiety assessment in children.

  • Jyothsna V Setty‎ et al.
  • Journal of dental anesthesia and pain medicine‎
  • 2019‎

Dental anxiety in children is a major barrier in patient management. If dental anxiety in pediatric patients is assessed during the first visit, it will not only aid in management but also help to identify patients who are in need of special care to deal with their fear. Nowadays, children and adults are highly interested in multimedia and are closely associated with them. Children usually prefer motion pictures on electronic devices than still cartoons on paper. Therefore, this study was conducted to evaluate a newly designed scale, the animated emoji scale (AES), which uses motion emoticons/animojis to assess dental anxiety in children during their first dental visit, and compare it with the Venham picture test (VPT) and facial image scale (FIS).


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