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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Permeable (PATO 0000982) ILX:0108763 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Peroxisome A small, membrane-bounded organelle that uses dioxygen (O2) to oxidize organic molecules; contains some enzymes that produce and others that degrade hydrogen peroxide (H2O2) (Gene Ontology). ILX:0108764 6 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Perphenazine An antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine. (PubChem) Pharmacology: Perphenazine is a piperazinyl phenothiazine, acts on the central nervous system, and has a greater behavioral potency than other phenothiazine derivatives whose side chains do not contain a piperazine moiety. It is a member of a class of drugs called phenothiazines, which are dopamine D1/D2 receptor antagonists. Perphenazine is 10 to 15 times as potent as chlorpromazine; that means perphenazine is a highly potent antipsychotic. In equivalent doses it has approximately the same frequency and severity of early and late extrapypramidal side-effects compared to Haloperidol. Mechanism of action: Binds to the dopamine D1 and dopamine D2 receptors and inhibits their activity. The mechanism of the anti-emetic effect is due predominantly to blockage of the dopamine D2 neurotransmitter receptors in the chemoreceptor trigger zone and vomiting centre. Perphenazine also binds the alpha andrenergic receptor. This receptor's action is mediated by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Drug type: Approved. Small Molecule. Drug category: Antipsychotic Agents. Antipsychotics. Dopamine Antagonists. Phenothiazines ILX:0108765 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Persistence Repetitiveness of rhythm. ILX:0108766 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Persistent Vegetative State Vegetative state refers to the neurocognitive status of individuals with severe brain damage, in whom physiologic functions (sleep-wake cycles, autonomic control, and breathing) persist, but awareness (including all cognitive function and emotion) is abolished (MeSH). ILX:0108767 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Person A being that has certain capacities or attributes constituting personhood. ILX:0108768 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Person Identification Code Sequence A code sequence idenitfying a person. ILX:0108769 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Person's Address Person's mailing address ILX:0108770 7 FDI Lab - SciCrunch.org 08/28/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Person's Telephone Numbers Person's telephone number(s) ILX:0108771 6 FDI Lab - SciCrunch.org 08/28/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Personal communication ILX:0108772 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pertinent Other Evidence Sequence Other Composite SOP Instances that are considered to be pertinent evidence by the creator of this SR Document. This evidence must have been acquired in order to satisfy Requested Procedures other than the one(s) for which this SR Document is generated. ILX:0108773 5 FDI Lab - SciCrunch.org 08/28/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Peruvian guinea pig ILX:0108774 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pervasive Development Disorder Severe distortions in the development of many basic psychological functions that are not normal for any stage in development. These distortions are manifested in sustained social impairment, speech abnormalities, and peculiar motor movements (MeSH). ILX:0108775 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pervasive developmental disorder not otherwise specified An autism spectrum disorder that involves some autistic symptoms occurring after age 3 with an absence of all the traits necessary for a diagnosis of autism. ILX:0108776 5 FDI Lab - SciCrunch.org 08/20/2021 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
PET imaging protocol Imaging in sections (sectioning), through the use of a wave-generating device (tomograph) that generates an image (a tomogram). ILX:0108777 5 FDI Lab - SciCrunch.org 08/01/2022 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pfizer An American multinational pharmaceutical corporation with a portfolio of products and medicines that support wellness and prevention, as well as treatment and cures for diseases across a broad range of therapeutic areas; and they have an industry-leading pipeline of promising new products that have the potential to challenge some of the most feared diseases of our time, like Alzheimer's disease and cancer.By revenues, it is one of the world's largest pharmaceutical companies. (Adapted from Wikipedia) ILX:0108778 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
PH Sensor Measures pH. Typically micro-pH electrodes based on solid state sensing technology, but can also be pH detection instrument that utilizes an optically based micro-sensor. ILX:0108779 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
PH-sensitive electrode recording protocol ILX:0108780 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Phalloidin Phalloidin is a peptide derived from the Death Cap mushroom that acts as a toxin by binding actin, inhibiting its depolymerization. Phalloidin binds specifically F-actin and is therefore a very convenient tool to investigate the distribution of F-actin since fluorescent analogs can be synthesized that retain actin binding. (Wikipedia) ILX:0108781 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Pharmacokinetics pharmacodynamics From BRO: (in Greek: "pharmacon" meaning drug and "kinetikos" meaning putting in motion, the study of time dependency; sometimes abbreviated as "PK") is a branch of pharmacology dedicated to the determination of the fate of substances administered externally to a living organism. In practice, this discipline is applied mainly to drug substances, though in principle it concerns itself with all manner of compounds ingested or otherwise delivered externally to an organism, such as nutrients, metabolites, hormones, toxins, etc.Pharmacokinetics is often studied in conjunction with pharmacodynamics. Pharmacodynamics explores what a drug does to the body, whereas pharmacokinetics explores what the body does to the drug. Pharmacokinetics includes the study of the mechanisms of absorption and distribution of an administered drug, the rate at which a drug action begins and the duration of the effect, the chemical changes of the substance in the body (e.g. by enzymes) and the effects and routes of excretion of the metabolites of the drug. - definition adapted from Wikipedia ILX:0108782 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb

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