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Label Description ILX Version Created CID Modified Time CID Type Created Time Status Creator Last modified
Neocortex primary motor area pyramidal layer 5 corticostriate cell This is a basic type of neocortical cell with a pyramidal-shaped cell body and basal and apical spiny dendrites. Its axon projects to the neostriatum, and gives off local collaterals with the neocortex. It belongs to the group termed intra-telenchephalic. ILX:0107381 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex primary motor area stellate layer 4 cell This basic type of neuron in the neocortex is characterized by a spherical cell body giving rise to multiple spiny dendrites radiating in many directions. . ILX:0107382 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex primary visual area pyramidal layer 2-3 cell ILX:0107383 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex primary visual layer 5 callosal cell Neuron in lower layer 5 of primary visual cortex with pyramidal or ovoid soma that project via the corpus callosum to the opposite visual cortex. At the area 17/18 border, callosal neurons are distributed evenly throughout the depth of layer 5. These neurons do not send projections to either the pontine nuclei or the superior colliculus. Apical dendrites of these cells were never observed to extend above layer 4. Basal dendrites were restricted to layer 5 and upper part of layer 6. 2-6 primary basal dendrites originated from the base of the pyramid or ovoid cell body. ILX:0107384 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex pyramidal cell Pyramidal neuron of the cerebral cortex (not including hippocampus or olfactory cortex).The pyramidal cell of the neocortex is located in layers 2-3 and 5-6, has a pyramidal-shaped cell body which gives off a number of laterally-directed basal dendrites and usually a single apical dendrite which ascends to branch and terminate in layer 1; these dendrites are covered in dendritic spines. ILX:0107385 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex pyramidal cell layer 5-6 The pyramidal cell of layer 5 of the neocortex has a pyramidal-shaped cell body which gives off a number of laterally-directed basal dendrites and usually a single apical dendrite which ascends to branch and terminate in layer 1; these dendrites are covered in dendritic spines. The axon descends through the internal capsule, giving off collaterals to the thalamus, to the medullary pyramids, where most of the axons cross controlaterally to descend and innervate the ventral horn of the spinal cord. ILX:0107386 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex pyramidal layer 2-3 cell This basic excitatory neuron type has a pyramidal-shaped cell body, with apical and basal dendrites. Typically, there is an axon that projects to other cortical and/or subcortical areas, as well as giving rise to local collaterals. ILX:0107387 6 FDI Lab - SciCrunch.org 01/17/2023 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex stellate cell ILX:0107388 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex stellate layer 4 cell ILX:0107389 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex stellate smooth cell A non-pyramidal neuron class found primarily in layer IV of mammalian neocortex characterized by relatively smooth dendrites (While and Rock, 1980). ILX:0107390 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neocortex stellate spiny cell A non-pyramidal neuron class found primarily in layer IV of mammalian neocortex characterized by a high density of dendritic spines (While and Rock, 1980). ILX:0107391 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neodentate part of dentate nucleus 'Neodentate part of dentate nucleus' is a gray matter of hindbrain. It is part of the dentate nucleus. ILX:0107392 12 FDI Lab - SciCrunch.org 01/17/2023 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neognathae ILX:0107393 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neognathi ILX:0107394 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neolepidoptera ILX:0107395 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neomycin A component of neomycin that is produced by Streptomyces fradiae. On hydrolysis it yields neamine and neobiosamine B. (From Merck Index, 11th ed) Pharmacology: Neomycin is an aminoglycoside antibiotic. Aminoglycosides work by binding to the bacterial 30S ribosomal subunit, causing misreading of t-RNA, leaving the bacterium unable to synthesize proteins vital to its growth. Aminoglycosides are useful primarily in infections involving aerobic, Gram-negative bacteria, such as Pseudomonas, Acinetobacter, and Enterobacter. In addition, some mycobacteria, including the bacteria that cause tuberculosis, are susceptible to aminoglycosides. Infections caused by Gram-positive bacteria can also be treated with aminoglycosides, but other types of antibiotics are more potent and less damaging to the host. In the past the aminoglycosides have been used in conjunction with penicillin-related antibiotics in streptococcal infections for their synergistic effects, particularly in endocarditis. Aminoglycosides are mostly ineffective against anaerobic bacteria, fungi and viruses. Mechanism of action: Aminoglycosides like neomycin "irreversibly" bind to specific 30S-subunit proteins and 16S rRNA. Specifically neomycin binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes. Drug type: Approved. Small Molecule. Withdrawn. Drug category: Aminoglycosides. Anti-Bacterial Agents. Antibiotics ILX:0107396 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Neonatal Abstinence Syndrome Fetal and neonatal addiction and withdrawal as a result of the mother's dependence on drugs during pregnancy. Withdrawal or abstinence symptoms develop shortly after birth. Symptoms exhibited are loud, high-pitched crying, sweating, yawning and gastrointestinal disturbances (MeSH). ILX:0107397 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Neonatal Myasthenia Gravis A disorder of neuromuscular transmission that occurs in a minority of newborns born to women with myasthenia gravis. Clinical features are usually present at birth or develop in the first 3 days of life and consist of hypotonia and impaired respiratory, suck, and swallowing abilities. This condition is associated with the passive transfer of acetylcholine receptor antibodies through the placenta. (MeSH). ILX:0107398 3 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex
Neoplasm disposition A disposition inhering in a tumour to progress or fail to progress during it's life time. ILX:0107399 4 FDI Lab - SciCrunch.org 08/24/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex troy sincomb
Neoptera ILX:0107400 4 FDI Lab - SciCrunch.org 06/18/2018 FDI Lab - SciCrunch.org term 12/09/2016 0 NeuroLex NeuroLex

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