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Total 959151 Results
| Label | Description | ILX | Version | Created CID | Modified Time | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Forcep | Forceps are used to grasp, move, or extract tissue and other objects. They are shaped like tweezers and their tips can have a variety of teeth or serrations. Tissue forceps contain teeth in patterns such as 1 x 2 (also known at rat tooth) to longitudinal 9 x 9 teeth (as in the Adson-Brown). Dressing forceps have either smooth or serrated jaws. | ILX:0104354 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forebrain | The part of the brain developed from the most rostral of the three primary vesicles of the embryonic neural tube and consisting of the DIENCEPHALON and TELENCEPHALON. (MSH) * part of the brain developed from the most rostral of the three primary vesicles of the embryonic neural tube (brain) from which the diencephalon and telencephalon are derived; also called the forebrain. (CSP), The part of the brain developed from the most rostral of the three primary vesicles of the embryonic neural tube and consisting of the Diencephalon and Telencephalon. | ILX:0104355 | 12 | FDI Lab - SciCrunch.org | 01/17/2023 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forebrain nucleus parcellation scheme | Parcellation scheme for nuclei in the forebrain | ILX:0104356 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forebrain of CIVM postnatal rat brain atlas | A superparcellation of the CIVM postnatal rat brain atlas consisting of the Diencephalon, the Hypothalamus, the Pineal Gland and the Telencephalon | ILX:0104357 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forebrain of WHS11 | Superparcellation of the Waxholm mouse brain atlas comprising the telencephalon and diencephalon | ILX:0104358 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forelimb | One of the pair of limbs that are situated anteriorly | ILX:0104359 | 8 | FDI Lab - SciCrunch.org | 06/23/2020 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Formalin test | ILX:0104360 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Formoterol | Formoterol is a long-acting beta2-agonist used in the management of asthma and/or chronic obstructive pulmonary disease (COPD). Inhaled formoterol works like other beta2-agonists, causing bronchodilatation by relaxing the smooth muscle in the airway so as to treat the exacerbation of asthma. Pharmacology: Formoterol is a long-acting selective beta2-adrenergic receptor agonist (beta2-agonist). Inhaled formoterol fumarate acts locally in the lung as a bronchodilator. In vitro studies have shown that formoterol has more than 200-fold greater agonist activity at beta2-receptors than at beta1- receptors. Although beta2-receptors are the predominant adrenergic receptors in bronchial smooth muscle and beta1-receptors are the predominant receptors in the heart, there are also beta2-receptors in the human heart comprising 10%-50% of the total beta-adrenergic receptors. The precise function of these receptors has not been established, but they raise the possibility that even highly selective beta2- agonists may have cardiac effects. Mechanism of action: The pharmacologic effects of beta2-adrenoceptor agonist drugs, including formoterol, are at least in part attributable to stimulation of intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3', 5'-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels cause relaxation of bronchial smooth muscle and inhibition of release of mediators of immediate hypersensitivity from cells, especially from mast cells. In vitro tests show that formoterol is an inhibitor of the release of mast cell mediators, such as histamine and leukotrienes, from the human lung. Formoterol also inhibits histamine-induced plasma albumin extravasation in anesthetized guinea pigs and inhibits allergen-induced eosinophil influx in dogs with airway hyper-responsiveness. The relevance of these in vitro and animal findings to humans is unknown. Drug type: Approved. Investigational. Small Molecule. Drug category: Adrenergic beta-Agonists. Bronchodilator Agents. Sympathomimetic | ILX:0104361 | 4 | FDI Lab - SciCrunch.org | 08/24/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | troy sincomb |
| Fornix | White matter structure carrying axons connecting the hippocampal formation to other brain regions. It is typically divided into the columns (crus), body, commissure and the pre-commissural and post-commissural fornix (MM). | ILX:0104362 | 15 | FDI Lab - SciCrunch.org | 01/17/2023 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Fornix of WHS11 | White matter structure delineated on T1 weighted MRI Waxholm mouse volume. As seen in coronal, dark tract caudal to anterior commissure. Traced intensity through coronal sections. | ILX:0104363 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Fourth lumbar spinal ganglion | The group of nerve cell bodies located on the dorsal spinal roots within the vertebral column at the level of the fourth lumbar vertebra | ILX:0104365 | 12 | FDI Lab - SciCrunch.org | 06/01/2022 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Fourth sacral spinal ganglion | ILX:0104367 | 13 | FDI Lab - SciCrunch.org | 06/01/2022 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Fourth thoracic spinal ganglion | The fourth thoracic dorsal root ganglion (or spinal ganglion; also known as a posterior root ganglion) is a cluster of neurons (a ganglion) in the fourth thoracic spinal nerve. | ILX:0104369 | 13 | FDI Lab - SciCrunch.org | 06/01/2022 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forum | users interact by posting questions, comments, bug reports, feature requests etc., typically supporting responses and discussion threads around the posts. Includes Issue trackers, wikis, Q&A sites, and forums. (CINERGI) | ILX:0104371 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forward digit span task | A method of short-term memory measurement in which a person listens to someone say a series of single-digit numbers and must repeat them back in the same order they were given. | ILX:0104372 | 4 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Forward scatter | Light scattering occurring at a wide angle (around 90 degrees) to the incident beam. | ILX:0104373 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| FOS | A class of nuclear leucine zipper proteins (FOS, FOSB, FOSL1, and FOSL2) that can dimerize with JUN Family proteins and bind DNA as the AP-1 transcription factor complex to regulate transcription in cell proliferation, differentiation. | ILX:0104374 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| FosB | ILX:0104375 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex | |
| Foscarnet | An antiviral agent used in the treatment of cytomegalovirus retinitis. Foscarnet also shows activity against human herpesviruses and HIV. (PubChem) Pharmacology: Foscarnet is an organic analogue of inorganic pyrophosphate that inhibits replication of herpes viruses in vitro including cytomegalovirus (CMV) and herpes simplex virus types 1 and 2 (HSV-1 and HSV-2). Foscarnet does not require activation (phosphorylation) by thymidine kinase or other kinases and therefore is active in vitro against HSV TK deficient mutants and CMV UL97 mutants. Thus, HSV strains resistant to acyclovir or CMV strains resistant to ganciclovir may be sensitive to foscarnet. However, acyclovir or ganciclovir resistant mutants with alterations in the viral DNA polymerase may be resistant to foscarnet and may not respond to therapy with foscarnet. The combination of foscarnet and ganciclovir has been shown to have enhanced activity in vitro. Mechanism of action: Foscarnet exerts its antiviral activity by a selective inhibition at the pyrophosphate binding site on virus-specific DNA polymerases at concentrations that do not affect cellular DNA polymerases. Drug type: Approved. Small Molecule. Drug category: Antiviral Agents. Reverse Transcriptase Inhibitors | ILX:0104376 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
| Fosfomycin | An antibiotic produced by Streptomyces fradiae. (PubChem) Pharmacology: Fosfomycin is a broad spectrum antibiotic that concentrates in kidney and bladder and is used to treat uncomplicated urinary tract infections. Fosfomycin also reduces nephrotoxicity and ototoxicity of platinum-containing anti-tumor agents. Mechanism of action: Fosfomycin is a phosphoenolpyruvate analogue produced by Streptomyces that irreversibly inhibits enolpyruvate transferase (MurA), which prevents the formation of N-acetylmuramic acid, an essential element of the peptidoglycan cell wall. Drug type: Approved. Small Molecule. Drug category: Anti-Bacterial Agents | ILX:0104377 | 3 | FDI Lab - SciCrunch.org | 06/18/2018 | FDI Lab - SciCrunch.org | term | 12/08/2016 | 0 | NeuroLex | NeuroLex |
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