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Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state.

Molecular metabolism | 2021

Metabolic diseases are an increasing problem in society with the brain-metabolic axis as a master regulator of the human body for sustaining homeostasis under metabolic stress. However, metabolic inflammation and disease will trigger sustained activation of the hypothalamic-pituitary-adrenal axis. In this study, we investigated the role of metabolic stress on progenitor cells in the hypothalamic-pituitary-adrenal axis.

Pubmed ID: 33157254 RIS Download

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This is a list of tools and resources that we have found mentioned in this publication.


BD FACSDiva Software (tool)

RRID:SCR_001456

A collection of tools for flow cytometer and application setup, data acquisition, and data analysis that help streamline flow cytometry workflows. It provides features to help users integrate flow systems into new application areas, including index sorting for stem cell and single-cell applications, as well as automation protocols for high-throughput and robotic laboratories.

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AxioVision Imaging System (tool)

RRID:SCR_002677

Digital image processing system where microscope settings and processing steps may be adjusted in single user interface. Can acquire images from variety of cameras. Includes software package for capturing, archiving and preparing images for publication. Allows users to visualize and present images in several dimensions. Functionality of imaging toolbox expands constantly with wide range of different modules that are tailored to specific applications or microscope accessories. This resource is duplicated by SCR_018376

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Promega (tool)

RRID:SCR_006724

An Antibody supplier

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BD Biosciences (tool)

RRID:SCR_013311

An Antibody supplier

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C57BL/6NRj (tool)

RRID:MGI:6236253

laboratory mouse with name C57BL/6NRj from MGI.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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