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Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression.

Molecular cancer | 2014

PTOV1 is an adaptor protein with functions in diverse processes, including gene transcription and protein translation, whose overexpression is associated with a higher proliferation index and tumor grade in prostate cancer (PC) and other neoplasms. Here we report its interaction with the Notch pathway and its involvement in PC progression.

Pubmed ID: 24684754 RIS Download

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PC-3 (tool)

RRID:CVCL_0035

Cell line PC-3 is a Cancer cell line with a species of origin Homo sapiens (Human)

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HeLa (tool)

RRID:CVCL_0030

Cell line HeLa is a Cancer cell line with a species of origin Homo sapiens

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HaCaT (tool)

RRID:CVCL_0038

Cell line HaCaT is a Spontaneously immortalized cell line with a species of origin Homo sapiens (Human)

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COS-7 (tool)

RRID:CVCL_0224

Cell line COS-7 is a Transformed cell line with a species of origin Chlorocebus aethiops (Green monkey)

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