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Intermittent losartan administration triggers cardiac post-conditioning in isolated rat hearts: role of BK2 receptors.

PloS one | 2014

The angiotensin (Ang) and bradykinin (BK) tissue-system plays a pivotal role in post-conditioning, but the efficacy of angiotensin type 1 receptor (AT1R) blockers (ARBs) in post-ischemic strategies is still under investigation. We evaluated functional and morphological outcomes, together with activation of cytosolic RISK pathway kinases, in rat hearts subjected to losartan (LOS) or irbesartan (IRB) post-ischemic administration.

Pubmed ID: 24520397 RIS Download

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SD (tool)

RRID:RGD_70508

Rattus norvegicus with name SD from RGD.

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