Hepatic insulin resistance impairs insulin's ability to suppress hepatic glucose production (HGP) and contributes to the development of type 2 diabetes (T2D). Although the interests to discover novel genes that modulate insulin sensitivity and HGP are high, it remains challenging to have a human cell based system to identify novel genes.
Pubmed ID: 22590537 RIS Download
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Cell line PLC/PRF/5 is a Cancer cell line with a species of origin Homo sapiens (Human)
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