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Identification of novel vascular markers through gene expression profiling of tumor-derived endothelium.

BMC genomics | 2008

Targeting tumor angiogenesis and vasculature is a promising strategy for the inhibition of tumor growth and dissemination. Evidence suggests that tumor vasculature expresses unique markers that distinguish it from normal vasculature. Our efforts focused on the molecular characterization of endothelial cells (EC) in the search for selective markers of tumor vasculature that might be helpful for the development of effective therapeutic approaches.

Pubmed ID: 18447899 RIS Download

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