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Early antibiotic exposure frequently induces gut dysbiosis in preterm infants. Although probiotics, such as the live combined preparation of Bacillus subtilis and Enterococcus faecium (LCBE), may mitigate this disruption, high-quality clinical evidence in this high-risk population remains limited. This prospective observational study investigated the association of early LCBE supplementation with the incidence of feeding intolerance (FI) and gut microbiota composition in antibiotic-exposed preterm infants.
Pubmed ID: 42239542
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