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The Role of lncRNA GAS5 in Oxidative Stress and Mitochondrial Dysfunction in Age-Related Cataracts: Insights From Transcriptome Profiling.

Deqian Kong | Yue Liu | Li Li | Huajun Wang | Ke Li | Tingting Zhang | Naisong Qi | Guangying Zheng
Investigative ophthalmology & visual science | 2026

This study aimed to investigate the role of lncRNA GAS5 and GADD45a in H₂O₂-induced oxidative stress and mitochondrial dysfunction in human lens epithelial cells (LECs), and to explore the underlying ceRNA mechanism involving miR-3666.

Pubmed ID: 42233724

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RNAhybrid (tool)

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