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Publication

Baicalein mitigates epithelial barrier impairment and microbiota dysbiosis in allergic asthmatic mice via the gut‑lung axis.

Yao Lu | Xinqian Rong | Lini Wei | Jingwen Yang | Kaiqi Zhang | Yong Tan | Ning Zhao | Xiaojuan He | Cheng Lu | Li Li
Chinese medicine | 2026

Allergic asthma (AA) may result in repeated episodes of chest constriction and coughing. In its most serious manifestations, it can cause death by asphyxiation. Currently, no efficacious therapeutic interventions exist to avert or counteract these serious outcomes. Baicalein (BAI) is a core quality marker of the traditional Chinese medicine Scutellaria baicalensis, but the mechanism of its oral action remains unclear.

Pubmed ID: 42169007

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Associated grants

  • Agency: The Fundamental Research Funds for the Central public welfare research institutes,
    Id: ZB2025013
  • Agency: Scientific and technological innovation project of China Academy of Chinese Medical Sciences,
    Id: CI2023C065YLL
  • Agency: Scientific Research Facility Special Foundation for Operation and Maintenance,
    Id: 102160222020040009016, 160202001000210007

Publication data is provided by the National Library of Medicine ® and PubMed ®. Data is retrieved from PubMed ® on a weekly schedule. For terms and conditions see the National Library of Medicine Terms and Conditions.

This is a list of tools and resources that we have found mentioned in this publication.

BALB/cAnNCrl (tool)

RRID:MGI:2683685

laboratory mouse with name BALB/cAnNCrl from MGI.

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The Stimulating Peripheral Activity to Relieve Conditions (SPARC) effort is the result of National Institutes of Health’s (NIH) drive to map out the neural circuitry responsible for visceral control in higher vertebrates. The SPARC Anatomy Working Group (SAWG) is responsible for the integrity of anatomical knowledge in SPARC

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