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Association of fructose-1,6-diphosphatase 1 with the progression of diabetic kidney disease.

Ziqi Fu | Zitong Chen | Shuaibo Bian | Li Li | Suheng Geng | Jiaxin Dong | Simeng Liu | Lin Wu | Jingfeng Zhu | Honglei Guo | Ao Bian | Kang Liu | Jiafa Ren | Changying Xing | Zhimin Huang | Huijuan Mao
Nutrition & metabolism | 2025

Diabetic Kidney Disease (DKD) is one of the most serious complications of diabetes mellitus, and a main cause of end-stage kidney disease (ESKD). The identification of clinically applicable molecular biomarkers for monitoring DKD progression has become increasingly essential. In this study, we aim to investigate the relationship between the expression of fructose-1,6-bisphosphatase 1 (FBP1), a rate-limiting enzyme in gluconeogenesis, and DKD.

Pubmed ID: 41225575

Research resources used in this publication

None found

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Associated grants

  • Agency: National Natural Science Foundation of China,
    Id: No.82200804
  • Agency: National Natural Science Foundation of China,
    Id: No. 82300775
  • Agency: National Natural Science Foundation of China,
    Id: No. 82470766
  • Agency: Chunhui Project Foundation of the Education Department of China,
    Id: No. HZKY20220176
  • Agency: Jiangsu Provincial Medical Key Discipline (Laboratory) Cultivation Unit,
    Id: JSDW202206
  • Agency: Specialized Diseases Clinical Research Fund of Jiangsu Province Hospital,
    Id: XB202408
  • Agency: Jiangsu Province Hospital (the First Affiliated Hospital with Nanjing Medical University) Clinical Capacity Enhancement Project,
    Id: JSPH-MA-2023-4
  • Agency: Clinical Diagnosis and Treatment Technology Innovation "Open Bidding and Leader Selecting" Project of Jiangsu Province Hospital,
    Id: JBGS202418

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