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Epigenetic regulation of NR5A2 influences colorectal cancer cell stemness via a stemness-related transcription factor NANOG.

Jia Liu | Li Li | Liang Zhang | Wenpeng Wang | Lei Zheng | Dalu Kong | Jiefu Wang | Yang Zhan
Cell communication and signaling : CCS | 2025

Colorectal cancer (CRC) is an aggressive malignancy with high mortality, and the identification of upstream regulators of stemness represents a critical step toward developing more effective targeted therapies. This study aimed to define the role of NR5A2 in CRC, particularly in the context of cancer stem cells (CSCs).

Pubmed ID: 41214698

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BALB/cAnN-Foxn1nu/nu/Rj (tool)

RRID:IMSR_RJ:BALB-C-NUDE

Mus musculus with name BALB/cAnN-Foxn1nu/nu/Rj from IMSR.

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